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Practical guidance for using rivaroxaban in patients with atrial fibrillation: balancing benefit and risk.

Rivaroxaban is a direct factor Xa inhibitor that is widely available to reduce the risk of stroke or systemic embolism in patients with nonvalvular atrial fibrillation and one or more risk factors for stroke. Rivaroxaban provides practical advantages compared with warfarin and other vitamin K antagonists, including a rapid onset of action, few drug interactions, no dietary interactions, a predicta

Measurement of the t(t)over-bar production cross-section as a function of jet multiplicity and jet transverse momentum in 7 TeV proton-proton collisions with the ATLAS detector

The t (t) over bar production cross-section dependence on jet multiplicity and jet transverse momentum is reported for proton-proton collisions at a centre-of-mass energy of 7 TeV in the single-lepton channel. The data were collected with the ATLAS detector at the CERN Large Hadron Collider and comprise the full 2011 data sample corresponding to an integrated luminosity of 4.6 fb(-1). Differential

Extraction-controlled quantum cascade lasers

A simple two-well design for terahertz quantum cascade lasers is proposed which is based on scattering injection and the efficient extraction of electrons from the lower laser level by resonant tunneling. In contrast to existing designs this extraction also controls the positive differential conductivity. The device is analyzed by calculations based on nonequilibrium Green's functions, which predi

Heat storage in forest biomass improves energy balance closure

Temperature measurements in trunks and branches in a mature ca. 100 years-old mixed pine and spruce forest in central Sweden were used to estimate the heat storage in the tree biomass. The estimated heat flux in the sample trees and data on biomass distributions were used to scale up to stand level biomass heat fluxes. The rate of change of sensible and latent heat storage in the air layer below t

Right-wing authoritarianism is a risk factor of torture-like abuse, but so is social dominance orientation

Right-wingauthoritarianism (RWA) is regularly implicated as a potential risk factor of abusive behavior, whereas social dominance orientation (SDO) is not. We compared RWA and the two subscales of SDO, SDO-Dominance and SDO-Egalitarianism, as factors behind legitimization and hypothetical self-involvement in the use of torture-like abusive behavior (a scenario from Abu-Ghraib military prison). Int

A taxonomy of planning and scheduling methods to support their more efficient use in construction project management

Purpose The implementation and control processes of project planning and scheduling involve a wide range of methods and tools. Despite the development and modification and integration of the project management theory with newer scheduling approaches in particular, practitioners’ views on the efficiency and effectiveness of these methods and tools differ. This situation can be attributed in part to

Constrained Multilinear Detection and Generalized Graph Motifs

We introduce a new algebraic sieving technique to detect constrained multilinear monomials in multivariate polynomial generating functions given by an evaluation oracle. The polynomials are assumed to have coefficients from a field of characteristic two. As applications of the technique, we show an O^∗(2^k)-time polynomial space algorithm for the k-sized Graph Motif problem. We also introduce a ne

Improved glucose regulation in type 2 diabetic patients with DPP-4 inhibitors: focus on alpha and beta cell function and lipid metabolism.

Inhibition of dipeptidyl peptidase-4 (DPP-4) is an established glucose-lowering strategy for the management of type 2 diabetes mellitus. DPP-4 inhibitors reduce both fasting and postprandial plasma glucose levels, resulting in reduced HbA1c with low risk for hypoglycaemia and weight gain. They act primarily by preventing inactivation of the incretin hormones glucose-dependent insulinotropic polype

WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.

Bladder exstrophy, a severe congenital urological malformation when a child is born with an open urinary bladder, is the most common form of bladder exstrophy-epispadias complex (BEEC) with an incidence of 1:30.000 children of Caucasian descent. Recent studies suggest that WNT genes may contribute to the etiology of bladder exstrophy. Here, we evaluated WNT pathway genes in 20 bladder exstrophy pa

Aktionsart, word form and context: On the use of the active participle in Gulf Arabic dialects

Abstract in UndeterminedA line has been drawn between the dialects of Oman and those of the coastal Gulf states in classifications of the Arabic dialects of the Arabian Peninsula (Johnstone 1967; Holes 1989 Holes 1996). Most studies reporting on this divide have dealt with the phonology, morphology and, to some extent, lexis. Little is known, however, about the degree to which these dialectal grou

Nematic Director Reorientation at Solid and Liquid Interfaces under Flow: SAXS Studies in a Microfluidic Device

In this work we investigate the interplay between flow and boundary condition effects on the orientation field of a thermotropic nematic liquid crystal under flow and confinement in a microfluidic device. Two types of experiments were performed using synchrotron small-angle X-ray-scattering (SAXS). In the first, a nematic liquid crystal flows through a square-channel cross section at varying flow

How to Select Active Space for Multiconfigurational Quantum Chemistry?

Bjorn Roos is one of the pioneers in the development and usage of multiconfigurational methods, in particular, the complete active space self-consistent field method and the perturbational complete active space perturbation theory through second order. To perform multiconfigurational calculations using these methods, a set of active orbitals must be selected, and the success of the methods depends

Ordovician sediments sandwiched between Proterozoic basement slivers: tectonic structures in the Stumsnas 1 drill core from the Siljan Ring, central Sweden

The Stumsnas 1 core, drilled in 2011 in the southern part of the Siljan Ring, represents a structurally complex section and provides new insights into the impact-induced local structure in central Sweden. The Siljan Ring was formed around the central uplift of a Late Devonian meteorite crater, the largest known impact structure in Europe. The Stumsnas 1 core section reveals that about 90m of Palae

Thin sequences and the Gram matrix

We provide a new proof of Volberg's Theorem characterizing thin interpolating sequences as those for which the Gram matrix associated to the normalized reproducing kernels is a compact perturbation of the identity. In the same paper, Volberg characterized sequences for which the Gram matrix is a compact perturbation of a unitary as well as those for which the Gram matrix is a Schatten-2 class pert

Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries.

Background/Objectives:Diets high in saturated and trans fat and low in unsaturated fat may increase type 2 diabetes (T2D) risk, but studies on foods high in fat per unit weight are sparse. We assessed whether the intake of vegetable oil, butter, margarine, nuts and seeds and cakes and cookies is related to incident T2D.Subjects/Methods:A case-cohort study was conducted, nested within eight countri

Effects of macroeconomic uncertainty on the stock and bond markets

In this paper we show that the long-run stock and bond volatility and the long-run stock-bond correlation depend on macroeconomic uncertainty. We use the mixed data sampling (MIDAS) econometric approach. The findings are in accordance with the flight-to-quality phenomenon when macroeconomic uncertainty is high. (C) 2015 Elsevier Inc. All rights reserved.