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Purpose: We assessed whether spinal inhibition of the cannabinoid degrading enzyme FAAH would have urodynamic effects in normal rats and rats with bladder overactivity induced by partial urethral obstruction or prostaglandin E2. We also determined the expression of FAAH, and the cannabinoid receptors CB1 and CB2 in the sacral spinal cord. Materials and Methods: We used 44 rats for functional (cyst
Chlorosomes from green photosynthetic bacteria belong to the most effective light-harvesting antennas found in nature. Quinones incorporated in bacterichlorophyll (BChl) c aggregates inside chlorosomes play an important redox-dependent photo-protection role against oxidative damage of bacterial reaction centers. Artificial BChl c aggregates with and without quinones were prepared. We applied hole-
The picture-change error on Douglas-Kroll-Hess (DKH) electron densities at atomic nuclei is analyzed in detail to high orders. Our results demonstrate that high-order DKH transformations of especially the property operator are needed to obtain converged results. However, if the convergence properties are discussed in terms of a relative error a fast convergence of the picture-change corrected DKH
This book is a contribution to the discussion about religion in contemporary Western society, characterized by the privatization of religion. The concept religion is not easily operational and does not carry meaning or implications that remain valid or consistent over time. It must be re-substantiated in order to remain descriptive and operational. This book’s ambition is to explore a means of re-
Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this technique is thermal motion of the DNA as it undergoes imaging; this blurs fluorescent patterns along the DNA and results in information loss. Correcting for this
Context: Although magnetic resonance imaging (MRI) is emerging as the most commonly used imaging modality for prostate cancer (PCa) detection, treatment planning, and follow-up, its acceptance has not been uniform. Recently, great interest has been shown in multiparametric MRI, which combines anatomic T2-weighted (T2W) imaging with MR spectroscopic imaging (MRSI), dynamic contrast-enhanced MRI (DC
Sveriges bygguniversitet är en organisation som har som syfte att främja samarbete inom byggrelaterad forskning och utbildningsverksamhet på Chalmers, LTH, LTU och KTH. Tanken är att en bättre samverkan kan bidra till att forskning och utbildning inom byggområdet blir mer effektiv och internationellt konkurrenskraftig. Projektet med att bilda Sveriges bygguniversitet löper mellan 2009-2010 och inn
This book analyses, in an international comparative context, Portugal´s energy transition from organic sources to fossil fuels in the period 1856-2006. It investigates the role that energy played in the industrialization of the country and how the relationship between energy and economic growth changed with the transition from an industrial to a service society. A unique dataset of energy quantiti
The European Spallation Source (ESS) in Lund, Sweden will become the world's leading neutron source for the study of materials by 2025. First neutrons will be produced in 2019. It will be a long pulse source, with an average beam power of 5 MW delivered to the target station. The pulse length will be 2.86 ms and the repetition rate 14 Hz. The ESS is presently in a design update phase, which ends i
Slips and falls and associated outdoor injuries are prevalent in cold climates. The objectives of this field investigation were to describe the consequences of slips and falls on ice and snow and the associated injuries, to assess the risks of various icy and snowy surfaces, to identify design needs of footwear, and to ascertain preventive measure preferences of outdoor workers. The organizations
Background: Within Europe many guidelines exist regarding the genetic testing of minors. Predictive and presymptomatic genetic testing of minors is recommended for disorders for which medical intervention/preventive measures exist, and for which early detection improves future medical health. Aim: This study, which is part of the larger 5th EU-framework "genetic education'' (GenEd) study, aimed to
We investigate soft gluon radiation off a quark-antiquark antenna in both color singlet and octet configurations traversing a dense medium. We demonstrate that, in both cases, multiple scatterings lead to a gradual decoherence of the antenna radiation as a function of the medium density. In particular, in the limit of a completely opaque medium, total decoherence is obtained, i.e., the quark and t
We report the results of an association study of melanoma that is based on the genome-wide imputation of the genotypes of 1,353 cases and 3,566 controls of European origin conducted by the GenoMEL consortium. This revealed an association between several SNPs in intron 8 of the FTO gene, including rs16953002, which replicated using 12,313 cases and 55,667 controls of European ancestry from Europe,
BACKGROUND: Policies that empower individuals and communities may be appropriate for public health, and more broadly. Simple, transparent and acceptable tools are therefore required to evaluate policies from an empowerment perspective. In 2008, the South African Department of Health (DOHSA) drafted a policy to endorse the integration of African Traditional Medicine (ATM) into the public health sec
Secondary angiosarcoma of the breast is a rare but severe long-term complication of breast cancer treated with breast-conserving surgery and radiotherapy. We characterized a population-based cohort of patients with secondary angiosarcomas from two tertiary hospitals to investigate this complication with respect to surgical treatment and outcome. We identified 35 patients with a history of radiatio
Taking the modern definition of ekphrasis as a verbal representation of a work of art as a starting point, we try to broaden it in this contribution. We agree with intermediality theorist Lars Elleström that ekphrasis falls into the category of “media representation”, defined as the representation of a source medium in a target medium. We argue that the target medium does not need to be a verbal o
