The structural heterogeneity of tumor tissue can be probed by diffusion MRI (dMRI) in terms of the variance of apparent diffusivities within a voxel. However, the link between the diffusional variance and the tissue heterogeneity is not well-established. To investigate this link we test the hypothesis that diffusional variance, caused by microscopic anisotropy and isotropic heterogeneity, is assoc

The analysis of signals on complex topologies modeled by graphs is a topic of increasing importance. Decompositions play a crucial role in the representation and processing of such information. Here, we propose a new tight frame design that is adapted to a class of signals on a graph. The construction starts from a prototype Meyer-type system of kernels with uniform subbands. The ensemble energy s

The aim of this thesis is to develop statistical models to reconstruct past land cover composition and human land use based on fossil pollen records over Europe for different time periods over the past 6000 years. Accurate maps of past land cover and human land use are needed when studying the interaction between climate and land surface, and the effects of human land use on past climate. Existing

Psykiatrilagsutredningens betänkande behandlar grundläggande frågor om vård, tvång, och straffrättslig ansvarsförmåga. Det handlar bl.a. om vem som kan samtycka till vård och behandling, när samhället kan tillgripa tvång för att förhindra någon från att skada sig själv eller annan. Det handlar också om vem som ska anses har förmåga att bära straffrättsligt ansvar för sina handlingar och de rättsli

I följande rapport redovisar vi resultatet från en utvärdering av datahanteringsplaner genomförd under 2016. Rapporten har följande disposition: bakgrund kring begreppet datahanteringsplaner, syfte och mål, avgränsningar, intressentanalys, risker, metod, resultat från forskarnas utvärdering, resultat från enkät till forskningsfinansiärer och slutligen en sammanfattning och rekommendation.

Rapporten omfattar en omvärldsanalys kring datahanteringsplaner, med analyser från utlandet och Sverige.

In this study the wet adhesion between Layer-by-Layer (LbL) assembled films of triblock copolymer micelles was investigated. Through the LbL assembly of triblock copolymer micelles with hydrophobic, low glass transition temperature (Tg) middle blocks and ionic outer blocks, a network of energy dissipating polymer chains with electrostatic interactions serving as crosslinks can be built. Four tribl

A mild procedure has been developed for the synthesis of α-keto amides by α-oxidation of the corresponding α-keto amines mediated by pyrrolidine and TEMPO. The method can also be applied to the synthesis of α-keto thioamides and α-keto amidines.

Diffusion är den slumpmässiga rörelse hos partiklar som drivs av deras kinetiska energi. Den är oftast osynlig för blotta ögat, men den utgör en viktig funktion för vår överlevnad. Diffusionen står bland annat för transporten av näringsämnen över cellmembran, och det är diffusionen som gör att ämnen i kroppen blandas så att livsviktiga kemiska reaktioner kan ske.Man kan undersöka diffusionsprocessDiffusion MRI provides a non-invasive probe of tissue microstructure. We recently proposed a novel method for diffusion-weighted imaging, so-called q-space trajectory encoding, that facilitates tensor-valued diffusion encoding. This method grants access to b-tensors with multiple shapes and enables us to probe previously unexplored aspects of the tissue microstructure. Specifically, we can disenta

A deep understanding of the behavior of microstructural parameters in proton exchange fuel cells (PEFCs) will help to reduce the material cost and to predict the performance of the device at cell scale. Changes in morphological configuration, that is, fiber diameter and fiber orientation, of the gas diffusion layers (GDLs) result in variations of fluid behavior throughout the layer, and therefore,

In the course of my PhD work, I have been involved in the development and the construction of the Tagging System for the BGO-OD experiment at the ELSA accelerators of the University of Bonn.BGO-OD is a fixed target experiment for the investigation of the structure of the nucleon at low energies via the photoproduction of mesons. It consist of a central calorimeter and a forward spectrometer. The r

The BGO-OD experiment is intended for the systematic investigation of the photo-production of mesons off the nucleon. The experiment will use bremsstrahlung photons from an e- beam incident upon a thin radiator. The photon energy will be measured via the deflection of the electrons in the magnetic field of a photon tagger. The B-FrED is a 16 channel double-threshold discriminator and shaper board

The LHCb Muon System consists of 122000 front-end channels, distributed on about 8000 front-end boards (on detector). 152 Off detector boards (each containing 192 channels) gather information from front-end and send it to the DAQ and trigger systems. The Muon System is highly configurable and is conceived to allow a deep control of the behavior of the whole system during data taking. This results

The LHCb system requires high efficiency muon detection into LHC bunch crossing: 95% into a 25 ns time window. To reach such efficiency many parameters of the detector readout apparatus have to be calibrated and adjusted and its channels must be aligned in time. In addition, essential characteristics must be monitored to guarantee a good working condition of the apparatus (to avoid loss of efficie

The LHCb experiment, presently under construction at CERN (European Center for Nuclear Research) Large Hadron Collider (LHC), aims at the study of CP violation in the B meson sector. Its key elements will be a Muon detector which allows triggering and muon identification from inclusive b decays. The electronic system of the whole detector is very complex and its Muon detector Experiment Control Sy

The LHCb muon readout apparatus is made of 1368 Multi-Wire Proportional Chambers (MWPC) and 24 Gas Electron Multiplier (GEM) chambers connected to 7632 16-channel front-end boards, resulting in 122.112 channels to be read out. After a pp collision, all the resulting signals must be read within 25 ns, before the next collision. The large-scale of the system and the time constrains naturally led to

The BGO Rugby Ball is a large solid angle electromagnetic calorimeter now installed in the ELSA Facility in Bonn. The BGO is operating in the BGO-OD experiment aiming to study meson photoproduction off proton and neutron induced by a Bremsstrahlung polarized gamma beam of energies from 0.2 to 3.2 GeV and an intensity of 5 × 107 photons per second. The scintillating material characteristics and the

The results obtained at the BGO-OD experiment with the BGO calorimeter, equipped with the new electronic readout based on sampling ADCs, during the tests performed with the beam time of March and June 2012 are presented. The proper functioning of the apparatus has allowed the reconstruction of the pseudo-scalar mesons π0 and η invariant masses. The simulation of the η' photoproduction reaction pre