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Tumor cells secreting IL-1 beta are invasive and metastatic, more than the parental line or control mock-transfected cells, and concomitantly induce in mice general immune suppression of T cell responses. Suppression strongly correlates with accumulation in the peripheral blood and spleen of CD11b(+)/Gr-1(+) immature myeloid cells and hematological alterations, such as splenomegaly, leukocytosis,

Force-velocity (F-V) relationships were determined for single frog muscle fibres during the rise of tetanic contraction. F-V curves obtained using isotonic shortening early in a tetanic contraction were different from those obtained at equivalent times with isovelocity shortening, apparently because changing activation early in the contraction leads, in isovelocity experiments, to changing force a

Nine patients with spondylarthropathy (SpA) (6 with ankylosing spondylitis and 3 with psoriatic arthritis) who had not responded properly to conventional DMARD therapy were treated with 3 infusions (at 0, 2 and 6 weeks) of the TNF alpha inhibitor infliximab (3 mg/kg), in combination with methotrexate. To measure the effect of treatment, patients were evaluated before as well as 8 and 12 weeks afte

A simple and inexpensive amperometric biosensor for formate detection was obtained by immobilization of for-mate dehydrogenase (FDH) on graphite powder, modified with a new phenothiazine derivative (DDDP; 16H, 18H-dibenzo[c,l]-7,9-dithia-16,18-diazapentacene). Two different enzyme environments were used: FDH was adsorbed on DDDP-modified graphite powder in the presence of polyethylenimine (PEI) as

A more than 40-year-long process came to an end when relations between the Church of Sweden and the state were formally changed in the year 2000. Social Democrats and Liberals had taken the initiative in the 1950s. Several proposals for disestablishment were put forward in the 1970s, but none of them. achieve political consensus. In addition, the representatives for all the political parties on th

This study aims to investigate the possibility of implementing serial autoradiography using a silicon strip detector as an imaging modality in pre-clinical radionuclide therapy research, in order to study the effect of non-uniform uptake on absorbed dose distribution and biological response. Tumor tissues expressing CD20 (B-cell lymphoma) or carcinoembryonic antigen (CEA; colorectal cancer) were e

Inclusive production cross sections are measured in deep inelastic scattering at HERA for meson states composed of a charm quark and a light antiquark or the charge conjugate. The measurements cover the kinematic region of photon virtuality 2 < Q(2) < 100 GeV2, inelasticity 0.05 < y < 0.7, D meson transverse momenta p(t)( D) greater than or equal to 2.5 GeV and pseudorapidity |eta( D)| less than o

Programming languages are the main tools used to describe models of the real world and algorithms which manipulate these models. Over time much effort has been devoted to the task of making programming languages more high-level by enhancing their expressiveness, bringing it closer to the way the programmer thinks and reasons. The development of object-oriented programming languages is one importan

Aim The aim of this work was to estimate C sequestration rates in the organic matter layer in Swedish forests. Location The region encompassed the forested area (23 x 10(6) ha) of Sweden ranging from about 55degrees N to 69degrees N. Methods We used the concept of limit values to estimate recalcitrant litter remains, and combined it with amount of litter fall. Four groups of tree species were iden

The diurnal hummingbird hawkmoth Macroglossum stellatarum can learn the achromatic (intensity-related) and the chromatic (wavelength-related) aspect of a spectral colour. Free-flying moths learn to discriminate two colours differing in the chromatic aspect of colour fast and with high precision. In contrast, they learn the discrimination of two stimuli differing in the achromatic aspect more slowl

Supported phospholipid bilayers (SPBs) have emerged as important model systems for studies of the natural cell membrane and its components, which are essential for the integrity and function of cells in all living organisms, and also constitute common targets for therapeutic drugs and in disease diagnosis. However, the preferential occurrence of spontaneous SPB formation on silicon-based substrate

The effects of whole-body exposure to ambient temperatures of -15 degrees C and 23 degrees C on selected performance-related physiological variables were investigated in elite nonasthmatic cross-country skiers. At an ambient temperature of -15 degrees C we also studied the effects of the selective beta2-adrenergic agonist Salbutamol (0.4 mg x 3) which was administered 10 min before the exercise te

Popular Abstract in Swedish Vad har den slaviskt inspirerade östersjökeramiken som arkeologer finner i Skandinavien med slaver att göra? Levde de som gäster i huset? Vikingen och hanseaten har sedan länge sina platser inbokade på den historiska scenen. Under äldre medeltid rörde sig även andra aktörer över Östersjöns vatten. Främmande gäster besökte och bosatte sig i Skandinavien. Bland dem fanns Scholarly texts on Slavic-Scandinavian relations have concentrated on two main areas of interest. During the Viking Age the economic and social contacts between the lake Mälaren district and Rus’ were extensive. However, at the beginning of the Middle Ages, political antagonism between the two expanding realms of the Svear and the Novgorodians is noticeable. In southern Scandinavia, the hostility

Thin layers of GaxIn1-xP grown on top of self-assembled InP quantum dots has been studied using transmission electron microscopy (TEM), scanning tunneling microscopy (STM), and low-temperature scanning tunneling luminescence (STL). STM reveals that the overgrowth is highly uneven, in which elongated GaxIn1-xP islands covering the dots are formed. TEM and high-spatial-resolution STL show that the q

The inclusive e(+)p single and double differential cross sections for neutral and charged current processes axe measured with the H1 detector at HERA. The data were taken in 1999 and 2000 at a centre-of-mass energy of roots = 319 GeV and correspond to an integrated luminosity of 65.2 pb(-1). The cross sections are measured in the range of four-momentum transfer squared Q(2) between 100 and 30 000

Popular Abstract in Swedish Den nuvarande teknologin inom förbränningsmotorer har möjligheten att hantera den alltmer strikta myndighetskraven på förbränningsmotorn. Emellertid de nödvändiga tekniska lösningarna som krävs är dyra och alltmer tekniskt krävande. En möjlig väg mot enklare efterbehandlingssystem är anvädningen av Homogen Kompressions Antändning (Eng: HCCI) motor cykeln. Den huvudsaklThe current technology within combustion engines have the possibility of handling the more stringent legislative demands on combustion engines. However the required solutions are getting more expensive and technically challenging. One possible way towards a more simple exhaust aftertreatment system is the use of the Homogeneous Charge Compression Ignition (HCCI) engine cycle. The main advantage o