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Urinary Apolipoprotein M Could Be Used as a Biomarker of Acute Renal Injury: An Ischemia-Reperfusion Injury Model of Kidney in Rat

Background. It has been well documented that apolipoprotein M (apoM) is principally expressed in hepatocytes as well as renal tubular epithelial cells. The importance of apoM in the kidney is unknown. In the present study we examined urinary any apoM after short-term ischemia-reperfusion injury (IRI) of kidney in a rat model. Methods. The kidneys of 11 male Sprague-Dawley rats were rendered ischem

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

Introduction: Potassium voltage-gated channel shaker-related subfamily member 5 (KCNA5) is implicated in vascular tone regulation, and its inhibition during hypoxia produces pulmonary vasoconstriction. Recently, a protective association of the KCNA5 locus with systemic sclerosis (SSc) patients with pulmonary arterial hypertension (PAH) was reported. Hence, the aim of this study was to replicate th

Origin of Mesoarchaean arc-related rocks with boninite/komatiite affinities from southern West Greenland

We report whole-rock elemental and Sm-Nd isotope geochemical data from mafic-ultramafic supracrustal rocks from the Nunatak 1390 area in southern West Greenland. Additionally, we report the metamorphic temperature history for these rocks as derived from tourmaline thermometry on a tourmalinite inlier, as well as in situ U-Pb, Hf and O isotopic data from zircons extracted from tonalite-trondhjemite

Vitamin d status in patients operated for primary hyperparathyroidism: comparison of patients from southern and northern europe.

Aim. The interaction between vitamin D deficiency and primary hyperparathyroidism (PHPT) is not fully understood. The aim of this study was to investigate whether patients with PHPT from Spain and Sweden differed in vitamin D status and PHPT disease activity before and after surgery. Methods. We compared two cohorts of postmenopausal women from Spain (n = 126) and Sweden (n = 128) that had first-t

Detection of Helicobacter rodentium-like DNA in the liver tissue of patients with chronic liver diseases by polymerase chain reaction-denaturing gradient gel electrophoresis and DNA sequence analysis

Many Helicobacter spp. were isolated from the stomach, intestinal tract, and liver of different animals and humans. The association between Helicobacter spp. and hepatobiliary diseases, including hepatocellular carcinoma, was thoroughly examined, indicating a potential role of the bacteria in the progression toward cancer. In our work, we screened 97 liver biopsies from patients with chronic liver

Range-resolved detection of potassium chloride using picosecond differential absorption light detection and ranging

A laser diagnostic concept for measurement of potassium chloride (KCl) and potentially other alkali compounds in large-scale boilers and furnaces of limited optical access is presented. Single-ended, range-resolved, quantitative detection of KCl is achieved by differential absorption light detection and ranging (DIAL) based on picosecond laser pulses. Picosecond DIAL results have been compared exp

A modified Lewis ECG lead system for ambulatory monitoring of atrial arrhythmias.

When using a reduced ECG lead system with three leads or less, the analysis of atrial activity during arrhythmias can become problematic due to low signal amplitude and noise. Long ago, Sir Thomas Lewis proposed a lead system for atrial activity enhancement in which two electrodes are placed directly on the chest, however, these leads are sensitive to arm movement artifacts. In this study, a modif

Putaminal Upregulation of FosB/Delta FosB-Like Immunoreactivity in Parkinson's Disease Patients with Dyskinesia

The transcription factor Delta FosB is a mediator of maladaptive neuroplasticity in animal models of Parkinson's disease (PD) and L-DOPA-induced dyskinesia. Using an antibody that recognizes all known isoforms of FosB and Delta FosB, we have examined the expression of these proteins in post-mortem basal ganglia sections from PD patients. The patient cases were classified as being dyskinetic or non

Mobility particle size spectrometers: harmonization of technical standards and data structure to facilitate high quality long-term observations of atmospheric particle number size distributions

Mobility particle size spectrometers often referred to as DMPS (Differential Mobility Particle Sizers) or SMPS (Scanning Mobility Particle Sizers) have found a wide range of applications in atmospheric aerosol research. However, comparability of measurements conducted world-wide is hampered by lack of generally accepted technical standards and guidelines with respect to the instrumental set-up, me

Increased C-Telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice.

The controlled assembly of collagen monomers into fibrils, with accompanying intermolecular cross-linking by lysyl oxidase-mediated bonds, is vital to the structural and mechanical integrity of connective tissues. This process is influenced by collagen-associated proteins, including Small Leucine-Rich Proteins (SLRPs), but the regulatory mechanisms are not well understood. Deficiency in fibromodul

A Heterogeneous Reconfigurable Cell Array for MIMO Signal Processing

This paper presents a heterogeneous reconfigurable cell array, designed for high-throughput baseband processing of multiple-input multiple-output (MIMO) systems. To achieve high performance and energy efficiency while retaining high flexibility, the proposed architecture adopts heterogeneous and hierarchical resource deployments. Additionally, extensive vector computation enhancements and flexible

Comparing energy crops for biogas production Yields, energy input and costs in cultivation using digestate and mineral fertilisation

Analyses of six crops grown in southern Sweden for biogas production (hemp, sugar beet, maize, triticale, grass/clover ley, winter wheat) showed varying performance regarding methane yield per hectare and energy input and costs in the production and supply of crops as biogas feedstock. The highest biomass and biogas yield was observed for sugar beet. Crops with lower risk of negative environmental

Approximating the parameter-space stability boundary considering post-contingency corrective controls

Lately, much work in the area of voltage stability assessment has been focused on finding post-contingency corrective controls. In this article a contribution to this area will be presented where we investigate the surface of maximal loadability while allowing for post-contingency corrective controls. This objective is different from the usual, where the aim is to include the post-contingency cont

Lentiviral gene transfer of TCIRG1 into peripheral blood CD34(+) cells restores osteoclast function in infantile malignant osteopetrosis.

Infantile malignant osteopetrosis (IMO) is a rare, lethal, autosomal recessive disorder characterized by non-functional osteoclasts. More than 50% of the patients have mutations in the TCIRG1 gene, encoding for a subunit of the osteoclast proton pump. The aim of this study was to restore the resorptive function of IMO osteoclasts by lentiviral mediated gene transfer of the TCIRG1 cDNA. CD34(+) cel

The willingness to pay-willingness to accept gap revisited: The role of emotions and moral satisfaction

While many earlier studies have found that people's maximum willingness to pay for having a good is often substantially lower than their minimum willingness to accept not having it, more recent experimental evidence suggests that this discrepancy vanishes for standard consumption goods when an incentive-compatible design without misconceptions is used. This paper hypothesises that there is neverth