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Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours

Popular Abstract in Swedish De flesta cancerformer uppvisar förvärvade kromosomavvikelser. En del enklare avvikelser har visat sig förekomma enbart i en viss tumörform och kan därför användas som diagnostiska markörer. I de flesta fall föreligger emellertid ett komplext och ospecifikt avvikelsemönster, ibland med ett mycket kraftigt ökat antal kopior av vissa DNA-sekvenser, så kallad genamplifieriAcquired genetic abnormalities are found in all types of malignant tumours and may contribute to neoplastic processes by altering protein structure or dosage. Many bone and soft tissue tumours (BSTT) are characterised by complex patterns of chromosome changes, including extensive intratumour heterogeneity and amplification of DNA sequences. The results presented in this thesis demonstrate that the

Discrete Optimal View Path Planning

This paper presents a discrete model of a sensor path planning problem, with a long-term planning horizon. The goal is to minimize the covariance of the reconstructed structures while meeting constraints on the length of the traversed path of the sensor. The sensor is restricted to move on a graph representing a discrete set of configurations, and additional constraints can be incorporated by alte

Performance analysis of cell zone partitioning in bandwidth reservation schemes

Bandwidth reservation is a procedure that can be applied to give higher priority to certain connection types in cellular networks. Subscriber movement predictions can be used to determine the amount of bandwidth to be reserved in each cell. The prediction accuracy is significantly unproved if both the approximate subscriber locations in the cell and stored subscriber movement data are taken into a

The effects of crayfish on interactions in freshwater benthic communities

Popular Abstract in Swedish Kräftors påverkan på födovävar i dammar och sjöarThis thesis examines how freshwater crayfish affect community interactions in benthic food webs. I have mainly studied the influence of the introduced signal crayfish (Pacifastacus leniusculus) on littoral communities, but also the influence of the native noble crayfish (Astacus astacus). Overall, the results show that both crayfish species are omnivores having strong direct and indirect effects o

Förändringsförsök och identitetsdramatisering. En studie bland nördar och slipsbärare

There is a vast amount of normative literature on change, which primarily focuses on how to manage change in an efficient and successful manner. What actually happens when management attempt to put their plans into practice is more seldomly investigated. Moreover, the prevailing literature on change primarily takes a management perspective. Other organizational members are usually treated as suppo