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Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno
Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i
Recension av Ian Buruma, Skuldbördan – hur Tyskland och Japan har gjort upp med andra världskriget.
This paper presents a three-dimensional sequentially coupled thermo-mechanical analysis of the friction stir welding process suitable for residual stress prediction. A friction stir butt weld of the aluminium alloy 2024 T3 is simulated using finite element analysis. The thermal model includes diffusive heat transfer in the work pieces and that backing plate, convective heat transfer in the work pi
Many birds use a flight mode called undulating or flap-gliding flight, where they alternate between flapping and gliding phases, while only a few bats make use of such a flight mode. Among birds, flap-gliding is commonly used by medium to large species, where it is regarded to have a lower energetic cost than continuously flapping flight. Here, we introduce a novel model for estimating the energet
Intervju: "När vi andra ser gungor, rutschbanor och berg- och dalbanor ser Ann-Marie Pendrill mängder av tillfällen att uppleva, prata om och räkna med fysik. – Fysik är ett lekfullt ämne."
Plate-like particles of SBA-15 form from smaller units (primary particles) that aggregate in an oriented manner. In this report we influence this aggregation by adding salt to the ongoing synthesis, generating well-ordered hexagonal p6m structure (SBA-15), with varying particle diameters. The additions, with either NaCl or NaI, were made at a time corresponding to the onset of oriented aggregation
It is important to evaluate each step in radiocarbon analysis to ensure that the whole process is as efficient and accurate as possible. Aerosol filter samples contain a myriad of carbonaceous compounds with varying resistance to oxidation. Complete combustion of the sample is thus of great importance to ensure that the graphitized sample is representative of the original filter sample. We have ev
Heart transplantation is life saving for patients with end-stage heart disease. However, a number of factors influence how well recipients and donor organs tolerate this procedure. The main objective of this study was to develop and validate a flexible risk model for prediction of survival after heart transplantation using the largest transplant registry in the world.
We studied 1,432 febrile travelers from Sweden who had returned from malaria-endemic areas during March 2005-March 2008. In 383 patients, paired serum samples were blindly analyzed for influenza and 7 other agents. For 21% of 115 patients with fever of unknown origin, serologic analysis showed that influenza was the major cause.
Adolescents with psychoses usually have full recovery from their first psychotic episode, but the first relapse often arises within 2 years of the first episode. Cannabis-related psychoses are difficult to distinguish from schizophrenic psychoses. Here, we describe a particularly severe clinical case, with a first psychotic episode occurring after heavy cannabis smoking, an atypically long symptom
Cancer cells within a given tumor were long regarded as a largely homogeneous group of cells originating from a common progenitor cell. However, it is increasingly appreciated that there is a considerable heterogeneity within tumors also on the tumor cell level. This heterogeneity extends to virtually all measurable properties of cancer cells, ranging from differentiation state, proliferation rate
We report on ultrafast spectroscopy study of beta-crustacyanin, the carotenoprotein responsible for the coloration of the lobster shell. beta-Crustacyanin is formed by two closely positioned astaxanthin molecules encapsulated in protein. The 2D electronic spectroscopy together with two-color pump-probe was applied to investigate the electronic structure, the excited-state dynamics, and the influen
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Chemokine receptor CX3CR1(+) dendritic cells (DCs) have been suggested to sample intestinal antigens by extending transepithelial dendrites into the gut lumen. Other studies identified CD103(+) DCs in the mucosa, which, through their ability to synthesize retinoic acid (RA), appear to be capable of generating typical signatures of intestinal adaptive immune responses. We report that CD103 and CX3C
Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (
Popular Abstract in Swedish Dieselmotorn lanserades för mer än ett sekel sedan och är nu den mest använda motorn inom Europas transportsektor. Detta beror framför allt på dess låga bränsleförbrukning och höga effekt. Avgasutsläppen är dieselmotorns största nackdel eftersom dessa biprodukter från förbränningen har negativa effekter både på folkhälsan och miljön. Därför regleras utsläppen genom lagsDiesel engines are widely used as powertrain solutions for transportation vehicles. Their low fuel consumption and high performance make them attractive, however, their associated pollutant emissions is a major drawback which represent a hazard for public health and the environment. Therefore, the concentrations of the major pollutant species are regulated. Soot, which to a large extent consists
