Development and validation of a method for analysis of immunosuppressive drugs in human dried blood spot samples, by means of liquid chromatography coupled to tandem mass spectrometry
Introduction: Dried blood spot sampling is an alternative way to conventional blood sampling that could potentially be a large benefit for certain patient groups. A good example is the transplanted patient group treated with the immunosuppressants everolimus and sirolimus. Background: The challenge is to develop a reliable quantification method based on this relatively novel sampling technique.
