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Model-Independent Femtoscopic Lévy Imaging for Elastic Proton-Proton Scattering

A model independent Lévy expansion method is introduced to describe nearly Lévy shaped squared moduli of Fourier transforms. We apply this method to precisely characterize the most recent elastic scattering data of proton-proton collisions at $$\sqrt s = 13$$ TeV. The results reveal a substructure of protons, which is found to be significantly larger and darker in high energy proton-proton collisi

Breaking the taboo: Eight Swedish Clinical Psychologists’ Experiences of Compassion Fatigue

Purpose: The aim of the study was to investigate the participating psychologists’ experiences with compassion fatigue, and to identify individual, interpersonal, and organizational factors and strategies perceived as contributing or protecting in relation to compassion fatigue. Methods: Semi-structured telephone interviews were conducted with eight psychologists (three men and five women) with mor

The risk of osteoporosis in patients with asthma

It is well-known that use of continuous systemic corticosteroids (SG) affects bone metabolism, bone mineral density (BMD), and ultimately increases the risk of osteoporosis. In patients with asthma, on the other hand, the effects of long-term high-dose inhaled corticosteroids (ICS) on BMD and risk of osteoporotic fractures is controversial. The reasons for this inconsistency could be explained by

Loss and Damage and limits to adaptation : recent IPCC insights and implications for climate science and policy

Recent evidence shows that climate change is leading to irreversible and existential impacts on vulnerable communities and countries across the globe. Among other effects, this has given rise to public debate and engagement around notions of climate crisis and emergency. The Loss and Damage (L&D) policy debate has emphasized these aspects over the last three decades. Yet, despite institutional

Shrunken pore syndrome - a common kidney disorder with high mortality. Diagnosis, prevalence, pathophysiology and treatment options

Invasive studies show that the glomerular sieving coefficients for 5–30 kDa plasma proteins in the human kidney may be selectively reduced compared to those for small molecules < 0.9 kDa, commonly used to measure glomerular filtration rate (GFR). Identification of this pathophysiological state, called shrunken pore syndrome (SPS), can easily and non-invasively be done by comparing estimations of G

Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma : the DSHNHL2006-1B/ACT-2 trial

PTCL patients exhibit poor survival with existing treatments. We investigated the efficacy of CHOP combined with alemtuzumab in 116 PTCL patients age 61–80 in an open-label, randomized phase 3 trial. Alemtuzumab was given on day 1, to a total of 360 mg in 21 patients, or 120 mg in 37. Hematotoxicity was increased with A-CHOP resulting in more grade ≥3 infections (40% versus 21%) and 4 versus 1 dea

Lifetime measurements of low-lying states in 73Ga and 70,72,74Zn isotopes

Lifetimes of low-lying states in 73Ga and 70,72,74Zn were measured using the Recoil Distance Doppler Shift (RDDS) method. These nuclei were produced in deep-inelastic reactions in inverse kinematics with a 208Pb beam impinging on a 76Ge target. Prompt γ rays were detected using the AGATA tracking array coupled to the VAMOS++ spectrometer. Lifetime of the 5/2- state in 73Ga, measured for the first

Palliative sedation via intraosseous vascular access : A safe and feasible way to obtain a vascular access end of life

Intraosseous (IO) access is normally reserved for emergencies and critical care conditions when venous cannulation is not possible. Nonetheless, we present a case of IO insertion to a 56-year-old man, tetraplegic for many years due to progressive spinal muscular atrophy and with refractory suffering. The IO access was used for palliative sedation with propofol in a home care setting. The patient d

Psychometric properties of the Neuropsychiatric Inventory for adults with intellectual disability

BACKGROUND: Problem behaviours are common among people with intellectual disabilities (ID), but psychometrically evaluated instruments for assessing such behaviours are scarce. The present study evaluated the psychometric properties of the Neuropsychiatric Inventory-Intellectual Disability (NPI-ID).METHOD: We assessed 108 residents with intellectual disabilities living in group-homes using the NPI

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

Epidemiology studies suggested that low birthweight was associated with a higher risk of hypertension in later life. However, little is known about the causality of such associations. In our study, we evaluated the causal association of low birthweight with adulthood hypertension following a standard analytic protocol using the study-level data of 183,433 participants from 60 studies (CHARGE-BIG c

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses accounting for gene-educational attainment interactions using two variables, “Some College” (yes/no) and “Graduated College” (yes/no). Interactions were evaluated using both

Bioinformatics resources for microbial research in biological systems

Bioinformatics is a continuously evolving field since it came into existence and contributing significantly in all major areas of biological sciences. Advanced sequencing technologies and exponential growth in computational resources have facilitated the high-end bioinformatics application in various research areas such as microbiome research in biological system. Bioinformatics contributed signif

Identification of the New Isotope 244Md

In an experiment performed at Lawrence Berkeley National Laboratory’s 88-inch cyclotron, the isotope 244Md was produced in the 209Bi(40Ar,5n) reaction. Decay properties of 244Md were measured at the focal plane of the Berkeley Gas-filled Separator, and the mass number assignment of A = 244 was confirmed with the apparatus for the identification of nuclide A. The isotope 244Md is reported to have o

A Family of Laminin α2 Chain-Deficient Mouse Mutants : Advancing the Research on LAMA2-CMD

The research on laminin α2 chain-deficient congenital muscular dystrophy (LAMA2-CMD) advanced rapidly in the last few decades, largely due to availability of good mouse models for the disease and a strong interest in preclinical studies from scientists all over the world. These mouse models continue to provide a solid platform for understanding the LAMA2-CMD pathology. In addition, they enable res

Systematic experimental study for optimized hydrogen production of Ni/CeO2 prepared by incipient wetness impregnation technique

In this present work, different supports (CeO2/ZrO2) and different Ni contents based catalysts were prepared by incipient wetness impregnation method and tested in the methane steam reforming (MSR) reaction. The prepared catalysts were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM). The XRD analysis confirmed the prepared Ni/CeO2 samples have a pure crystal structu

Sub-Kelvin hysteresis of the dilanthanide single-molecule magnet Tb2ScN@ C80

Magnetic hysteresis is a direct manifestation of nonequilibrium physics that has to be understood if a system is to be used for information storage and processing. The dilanthanide endofullerene Tb2ScN@C80 is shown to be a single-molecule magnet with a remanence time on the order of 100 s at 400 mK. Three different temperature-dependent relaxation barriers are discerned. The lowest 1 K barrier is

Drivers of abrupt and gradual changes in agricultural systems in Chad

The countries in the Sahel are undergoing rapid changes due to a mixture of demographic, ecological, and economic transformations. Rural livelihoods in these countries are predominantly engaged in agriculture, which is a foundational component of both food security and the general economy. The relationships between ongoing socio-economic transformation and the agricultural sector are clearly impor

On the role of the frontal projection in videoradiography of velopharynx in decision-making for a velopharyngeal flap plasty in patients with cleft palate

Despite uneventful primary surgery, patients with cleft palate may experience velopharyngeal insufficiency (VPI) and hypernasal speech. Videoradiography of velopharynx is a commonly used method to visualize velopharyngeal function and a velopharyngeal flap is often used to counteract VPI. The aim of this study was to investigate whether the frontal projection on videoradiography plays a role in th

Reflection in higher music education : what, why, wherefore?

Reflective practice is seen as a method for professional growth and lasting learning outcomes, but what this means in the context of Higher Music Education (HME) has not received sufficient attention. This paper explores how reflection is ontologised and justified as part of performing musicians’ education. The data utilised derive from a comprehensive project investigating how processes of academ

A key-recovery timing attack on post-quantum primitives using the Fujisaki-Okamoto transformation and its application on FrodoKEM

In the implementation of post-quantum primitives, it is well known that all computations that handle secret information need to be implemented to run in constant time. Using the Fujisaki-Okamoto transformation or any of its different variants, a CPA-secure primitive can be converted into an IND-CCA secure KEM. In this paper we show that although the transformation does not handle secret informatio