Quantification of myocardial and liver iron load has become a mainstay of guiding therapy in thalassaemia patients. However, current quantification methods are user dependent for data-point exclusion before curve fitting, and do not report the T2* certainty. Recently, an automatic inline maximum likelihood estimate (MLE) method with k-space Rician noise correction was validated against the referen

Validated planet candidates need not lie on long-term stable orbits, and instability triggered by post-main-sequence stellar evolution can generate architectures which transport rocky material to white dwarfs, hence polluting them. The giant planet HD 131399Ab orbits its parent A star at a projected separation of about 50-100 au. The host star, HD 131399A, is part of a hierarchical triple with HD

Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. R

In this paper two architectures for tunable duplexersare presented. The tuning is accomplished through variablecapacitance and resistance. The architectures are based on athree element series-parallel resonator, with one pass and onestop frequency. Both architectures rely on filtering as well ascancellation for good Tx to Rx isolation while maintaining lowinsertion loss. The first architecture, the

Background: Accurate assessment of myocardium at risk (MaR) after acute myocardial infarction (AMI) is necessary when assessing myocardial salvage. Contrast-enhanced steady-state free precession (CE-SSFP) is a recently developed cardiovascular magnetic resonance (CMR) method for assessment of MaR up to 1 week after AMI. Our aim was to validate CE-SSFP for determination of MaR in an experimental po

OBJECTIVES:: To study the prognostic value of fever in the emergency department in septic patients subsequently admitted to the ICU. DESIGN:: Observational cohort study from the Swedish national quality register for sepsis. SETTING:: Thirty ICU’s in Sweden. PATIENTS:: Two thousand two hundred twenty-five adults who were admitted to an ICU within 24 hours of hospital arrival with a diagnosis of sev

I april 2016 gick föreningens vårexkursion till trakterna runt Växjö, med några helt skilda miljöer som mål. Här redogör Emil Persson och Ulf Arup för exkursionen som innebar deltagarrekord med god marginal. Första dagen deltog hela 56 personer.

Aquaporins are transmembrane proteins that facilitate the flow of water through cellular membranes. An unusual characteristic of yeast aquaporins is that they frequently contain an extended N terminus of unknown function. Here we present the X-ray structure of the yeast aquaporin Aqy1 from Pichia pastoris at 1.15 Å resolution. Our crystal structure reveals that the water channel is closed by the N

Detta är en monografi skriven i samarbete med litteraturvetaren Ingemar Oscarsson. Boken bygger på ett opublicerat franskt 1600-tals manuskript, ms. 1143, som bär titeln Mémoires d’un voyage fait dans les pays septentrionaux en l’an M.D.C.LXIII. Originalmaterialet är ett inbundet dokument i kvartoformat på 280 handskrivna sidor.

Molecular dynamics simulations, binding free energy calculations, principle component analysis (PCA), and residue interaction network analysis were employed in order to investigate the molecular mechanism of M184I single mutation which played pivotal role in making the HIV-1 reverse transcriptase (RT) totally resistant to lamivudine. Results showed that single mutations at residue 184 of RT caused

This book is the first to explore the history of the Swedish electronic music studio EMS. EMS was established in 1964 with the intent to create an international center for research in sound and sound perception, and to build one of the world’s most advanced hybrid studios. The principal creators of the studio were rooted in Swedish modernism, and had the EMS-project shaped in accordance to the soc

The aim of the study was to evaluate from the ethical point of view the importance of transient muscular jerks commonly exhibited by swine at an early stage of pre‐slaughter CO2 anaesthesia. The influence of 5 min restraint upon plasma concentrations of adrenaline (A) and noradrenaline (NA) was studied in swine (n= 6) before and after bilateral lesioning of the amygdaloid region of the brain, as w

The aim of this work was to study the effect of time between adrenaline injection and slaughter on the rate and extent of post-mortem metabolism in pig muscle. Five pigs were subcutaneously injected with adrenaline (0·3 mg/kg) or with a saline solution 4 h, 1 h or 15 min prior to slaughter. pH1, pHu and FOPu were measured in Longissimus dorsi (LD) and Biceps femoris (BF) muscles. m.LD samples were

Channel modeling studies in vehicle-to-vehicle (V2V) communications have shown that larger road users act as blocking objects for the communication of surrounding vehicles, dramatically altering the statistical properties of the wireless channel. Without a strong line-of-sight component, packet delivery depends on other propagation mechanisms that are statistically more likely to add destructively

Reaction of Ru3(CO)12 with tris(2-thienyl)phosphine (PTh3) in CH2Cl2 at room temperature or in THF in the presence of a catalytic amount of Na[Ph2CO] furnishes the carbonyl substitution products Ru3(CO)11(PTh3) (1), Ru3(CO)10(PTh3)2 (2), and Ru3(CO)9(PTh3)3 (3). Heating 1 in toluene affords the cyclometalated cluster Ru3(CO)9{μ-Th2P(C4H2S)}(μ-H) (4) resulting from carbonyl loss and carbon-hydrogen