Several high resolution electrophysiological techniques such as measurements of cell membrane capacitance and amperometry are used to detect exocytotic events. A novel method was developed in this study based on the expression of P2X2 receptor channel in secreting cells. The presence of ATP sensitive channel on the cell membrane permitted the electrical detection of minute (amoles) quantities of A

Modern tools in proteomics require access to large arrays of specific binders for use in multiplex array formats, such as microarrays, to decipher complex biological processes. Combinatorial protein libraries offer a solution to the generation of collections of specific binders, but unit operations in the process to isolate binders from such libraries must be automatable to ensure an efficient pro

Attosecond pulses allow the study of electrons on their natural timescale. They are created from the interaction of atoms with ultrashort, intense laser pulses whose electric field approaches the strength of inner-atomic electric fields. This thesis presents experiments around the generation, characterization and application of attosecond pulses. First, we study the influence of the atomic genera

This study measures the impact of fanya juu terraces on the net value of crop income in a high-rainfall area in the Ethiopian highlands using cross-sectional multiple plot observations. Using propensity score matching methods we find that the net value of crop income for plots with fanya juu terraces is lower than for plots without fanya juu terraces. This finding makes it difficult to avoid concl

We present theoretical methods and computational strategies of the effects of nanoparticles on linear optical properties of molecules. We present quantum mechanical-molecular mechanics response methods for calculating electromagnetic properties of molecules interacting with nanoparticles and we report strategies for calculating electronic and redox states of molecules sandwiched between gold nanop

OBJECTIVE: To evaluate the effects of intrauterine growth restriction (IUGR) with absent or reversed end-diastolic blood flow in the umbilical artery and very preterm birth on cognitive outcome at 5 to 8 years of age. METHODS: We studied 34 children with IUGR born at a median of 26.9 gestational weeks (GWs) (range: 24-29 GWs) (PT-IUGR), 34 matched preterm appropriate-for-gestational age (PT-AGA) c

In Weber's writing and in leadership theory, charismatic leadership is associated with social change However, the importance and desirability of charismatic leaders in change processes can be questioned, as well as the notion that charismatic leaders are invariably proponents of change There are documented cases of charismatic leaders in religious and political contexts who have opposed ongoing ch

Abstract in Danish Amning har sundhedsmæssige fordele for mor og barn og mere udtalte fordele for præmature børn, men udenlandske undersøgelser viser, at færre præmature børn påbegynder amning, og færre præmature børn ammes i 4 og 6 måneder sammenlignet med mature børn. Der findes ikke danske undersøgelser om andelen af præmature børn, som påbegynder amning, men en dansk undersøgelse viser, at 60 Breastfeeding has even more pronounced health benefits for preterm infants than for full-term infants, but preterm infants are less breastfed. There is no consensus in Danish neonatal intensive care units (NICUs) about which clinical methods facilitate breastfeeding. Skin-to-skin contact between infant and parent is the first step in the breastfeeding process for preterm infants, but studies of to

Removal of seven active pharmaceutical substances (ibuprofen, ketoprofen, naproxen, diclofenac, clofibric acid, mefenamic acid, and gemfibrozil) was assessed by batch experiments, with suspended biofilm carriers and activated sludge from several full-scale wastewater treatment plants. A distinct difference between nitrifying activated sludge and suspended biofilm carrier removal of several pharmac

Understanding of molecular mechanisms underlying the effects of cell cycle proteins in response to the chemotherapeutic agents is of great importance for improving the efficacy of targeted therapeutics and overcoming resistance to chemotherapeutic agents. Staurosporine and tumor necrosis factor alpha (TNFalpha) are the therapeutic agents that inhibit tumor cell growth by inducing cell death. Staur

Recension av Tarak Barkawi & Keith (eds.), Orientalism and War.

Context. In 1992 we began a precision radial velocity survey for planets around solar-like stars with the Coude Echelle Spectrograph and the Long Camera (CES LC) at the 1.4m telescope in La Silla (Chile) resulting in the discovery of the planet iota Hor b. We have continued the survey with the upgraded CES Very Long Camera (VLC) and the HARPS spectrographs, both at the 3.6m telescope, until 2007.

Background: Knowledge of sitting and standing performance in a total population of children with cerebral palsy (CP) is of interest for health care planning and for prediction of future ability in the individual child. In 1994, a register and a health care programme for children with CP in southern Sweden was initiated. In the programme information on how the child usually sits, stands, stands up

Background: There is a worldwide obesity epidemic, but lack of a simple method, applicable for research or clinical use, to identify individuals at high risk of weight gain. Therefore, the relationship of self-rated health and 10-year percent weight change was evaluated to determine if self-rated health would predict weight change. Methods: From 1990 to 2008, adults aged 30, 40, 50 and 60 years we

This study examined the control of voice intensity using acoustic and aerodynamic recordings. A total of 34 subjects participated half of them with and half without song training, 21 females and 13 males. The subjects produced the syllable sequence /papapa/ while the acoustic signal, the oral air flow, and the oral air pressure were recorded using the Kay-Pentax Phonatory Aerodynamic System. The o

Abstract More than 300 million people are suffering from diabetes worldwide and the numbers of diabetic patients are increasing. Today´s treatments mainly rely on daily insulin injections. This help people to control blood glucose levels but still many patients suffer from the many complications associated with diabetes. Transplantations of islet cells are an alternative treatment that could help

We have designed and tested economical large-area RF strip-line anodes made by silk-screening silver onto inexpensive plate glass, for use in microchannel plate photodetectors to provide measurements of time, position, integrated charge, and pulse waveform shapes. The 229-mm-long anodes are modular, and can be attached in series for economy in electronics channel-count. Measurements of the anode i