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Background: Decision-making regarding treatment limitations such as “Do not attempt resuscitation” (DNAR) orders for older patients has been found deficient. Patients ≥ 80 years with substantial comorbidity have little chance of surviving cardiac arrest, thus require thorough risk classification focusing on comorbidity and frailty. This study aimed to explore the degree of frailty, comorbidity and

Background: Previous literature indicate retinal hyperspectral imaging as a non-invasive method with the potential for identifying amyloid-beta (Aβ) protein deposits. Current diagnostic methods, such as cerebrospinal fluid analysis or positron emission tomography, are costly, invasive, and non-scalable. Hyperspectral imaging offers a potentially accessible alternative for early detection of Alzhei

Peanut (Arachis hypogaea L.) is globally recognized as an important oilseed crop. Traits related to plant architecture are closely associated with yield in peanut. In this study, we focused on four specific traits related to plant architecture—first branch length (FBL), main stem height (MSH), stem diameter (SD), and the number of nodes on the main stem (NSK)—across three locations. Using whole-ge

The transcriptional co-activators YAP (YAP1) and TAZ (WWTR1) are central regulators of vascular smooth muscle cell (VSMC) phenotype and vascular homeostasis. This study investigates the consequences of VSMC-specific YAP/TAZ deletion and its relevance to atherosclerosis. Using bulk and single-cell RNA sequencing data, we demonstrate that gene expression changes following two (2-week YT) and eight w

Compartmentalized microfluidic platforms are an invaluable tool in neuroscience research. However, harnessing the full potential of this technology remains hindered by the lack of a simple fabrication approach for the creation of intricate device architectures with high-aspect ratio features. Here, a hybrid additive manufacturing approach is presented for the fabrication of open-well compartmental

We examine the favorable propagation (FP) behavior of a massive multi-user multiple-input-multiple-output (MU-MIMO) system equipped with a uniform linear array (ULA), horizontal uniform rectangular array (HURA) or uniform circular array (UCA) using a ray-based channel model with user cluster sharing. We demonstrate FP for these systems and provide analytical expressions for the mean-squared distan

Extractives found in the heartwood of a moderately durable conifer (Larix gmelinii var. japonica) were compared with those found in a non-durable one (Picea abies). We identified and quantified heartwood extractives by extraction with solvents of different polarities and gas chromatography with mass spectral detection (GC-MS). Among the extracted compounds, there was a much higher amount of hydrop

Syftet med den här texten är att stå upp till det professionella sociala arbetets försvar genom ett kritiskt förhållningssätt till både forskare och socionomer/praktiker i socialt arbete. Vad gäller forskare riktas blicken framförallt mot forskarkarriären, och vad gäller socionomer uppmärksammas yrkesutövningen på den fältbaserade praktiken med fokus på kommunal aktivering av arbetslösa och brukar

BackgroundSweden has in recent years witnessed increasing rates of firearm-related violence and homicide, which has contributed to increased rates of deadly violence. Attempts to profile offenders committing such crimes are of major importance, because such efforts may contribute to better preventive measures. We therefore aimed to study the characteristics of individuals convicted and/or suspecte

I Tolkning av entreprenadavtal behandlas praktiskt återkommande tolkningsfrågor som aktualiserar tolkning av villkor i andra kontraktshandlingar än Allmänna bestämmelser. Detta sker mot bakgrund av såväl Högsta domstolens praxis som avgöranden från underrätterna. Boken riktar sig till praktiskt verksamma jurister samt ingenjörer och andra yrkesgrupper som regelbundet arbetar med entreprenadavtal.

Falkheimer and Heide further develop their integration of improvisation into crisis communication. They argue that improvisation is a way to develop innovative thinking. Falkheimer and Heide argue crisis managers must adapt to new circumstances and situations making improvisation a value asset. Drawing from the leadership literature, they develop the idea of strategic improvisation. Strategic impr

Background: Obesity among children and adolescents is a worldwide public health concern. Type 1 diabetes (T1D) and type 2 diabetes (T2D) incidence are increasing, with heredity and socioeconomic status as possible risk factors. How these factors affect the risk of childhood obesity remains unclear. The aim of this study was to investigate the association between obesity and parental diabetes among

Surrogacy has been a legal practice in Ukraine since 2000. Being a cheaper option (surrogacy in Ukraine costs around USD 50.000 compared to USD 100.000 in the USA), Ukraine became an even hotter spot after other popular destinations, such as India, Nepal, and Thailand, banned compensated surrogacy for foreigners. Moreover, this is not only the price tag that made Ukraine such an appealing option.

Regulation of insulin signaling by microRNAs in smooth muscle cells may contribute to diabetic vascular disease. The two smooth muscle enriched miRNAs miR-143 and miR-145 have been reported to target mediators of insulin signaling in non-smooth muscle cells. In this study, we aimed to determine the importance of this regulation in vascular smooth muscle cells, where expression of miR-143/145 is mu