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The Swedish National Library published together with the university libraries in Gothenburg, Lund, Stockholm, Umeå and Uppsala in January 2020 a Declaration of Intent where the goal to digitiz Swedish print from the 15th century until today was formulated. Based on this objective, the article discusses different digitization strategies in libraries. Mass digitization stands for the rapid digitizat

Criminal recidivism is a major global concern. There is a well-known association between substance use disorders and offending. Yet, little is known about crime-specific recidivism. The aim of this study was to investigate the relationship between specific substance use and crime-specific recidivism. The study is based on 4207 Swedish prison clients with substance use assessed with Addiction Sever

We show how the interplay between feedback and mass-growth histories introduces scatter in the relationship between stellar and neutral gas properties of field faint dwarf galaxies (M∗ 106, M⊙). Across a suite of cosmological, high-resolution zoomed simulations, we find that dwarf galaxies of stellar masses 105 ≤ M∗ ≤ 106, M⊙ are bimodal in their cold gas content, being either H i-rich or H i-defi

In this work we discuss two different phases of a complex singlet extension of the Standard Model (SM) together with an extension that also includes new fermion fields, in particular, a Majoron model equipped with an inverse seesaw mechanism. All considered scenarios contain a global U(1) symmetry and allow for first-order phase transitions while only two of them are strong enough to favour the de

BACKGROUND: Intraabdominal and retroperitoneal sarcomas (IaRS) are malignant connective tissue tumors. Surgical resection is often the only curative treatment. The primary objective was to report the mid-term outcomes following contemporary treatment protocols and identify prognostic factors.METHODS: A retrospective review of consecutive patients (n = 107) with IaRS treated at single center from 2

T lymphocyte acute lymphoblastic leukemia (T-ALL) is a heterogeneous disease affecting T cells at multiple stages of their development and is characterized by frequent genomic alterations. The transcription factor LEF1 is inactivated through mutation in a subset of T-ALL cases but elevated LEF1 expression and activating mutations have also been identified in this disease. Here we show, in a murine

Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders such as acne vulgaris. The availability of the complete genome sequences from various C. acnes clades have enabled the identification of putative methyltransferases, some of the

Feedbacks between the intertwined water and carbon cycles in semi-arid mountain ecosystems can introduce large uncertainties into projections of carbon storage. In this study, we sought to understand the influence of key mechanisms on carbon balances, focusing on an ecosystem whose complex terrain and large interannual variability in precipitation adds to its vulnerability to warming. We applied a

Background: Up to now, there are no clinically available minimally invasive biomarkers to accurately identify mild cognitive impairment (MCI) patients who are at greater risk to progress to Alzheimer’s disease (AD) dementia. The recent advent of blood-based markers opens the door for more accessible biomarkers. We aimed to identify which combinations of AD related plasma biomarkers and other easil

Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,

This paper presents an analysis of channel characteristics for an outdoor scenario at the frequency band of 28-30 GHz. A geometry-based clustering algorithm is proposed to group the measured multipath components (MPCs) based on the interaction points on the surrounding walls or objects obtained from Ray Tracing 3-D simulations, which is more physically interpretable than the traditional clustering

The harmonic structure is a recently introduced concept paving the way for engineering metallic materials to achieve excellent mechanical performance. They consist of soft coarse-grained regions (Core) that are three-dimensionally surrounded by a connected network of hard ultra-fine grained regions (Shell). The interaction in these Core–Shell regions produces a synergistic effect, during plastic d

Teaching and learning could be guided by psychological knowledge to a larger extent. The aims of this study were to examine school psychologists’ (N = 117) assessments of how psychological constructs related to learning are being used by teachers in Swedish schools. In addition, we aimed to evaluate school psychologists’ awareness of teachers’ implementation of psychological knowledge. A theoretic

Background: Half the children with high-risk neuroblastoma die with widespread metastases. Molecular radiotherapy is an attractive systemic treatment for this relatively radiosensitive tumor. 131I-mIBG is the most widely used form in current use, but is not universally effective. Clinical trials of 177Lutetium DOTATATE have so far had disappointing results, possibly because the administered activi

Protein homeostasis is fundamental to cell function and survival. It relies on an interconnected network of processes involving protein synthesis, folding, post-translational modification and degradation as well as regulators of these processes. Here we provide an update on the roles, regulation and subcellular localization of the protein homeostasis machinery in the Gram-positive model organism B

The Zn K-edge X-ray absorption spectroscopy is used to investigate in situ the decomposition of zinc peroxide ((Formula presented.)) to zinc oxide (ZnO). Principal component and linear combination analyses of the extended X-ray absorption fine structure (EXAFS) spectra are employed to identify the phase composition of the oxide upon heating to 900 °C. Only the (Formula presented.) phase is found u