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Oral direct inhibitors (ODIs) of thrombin and factor Xa are now approved as anticoagulant drugs. The first two drugs to complete phase III clinical trials for thromboprophylaxis in orthopaedic surgery and treatment of patients with atrial fibrillation or venous thromboembolism were dabigatran and rivaroxaban. These small molecules are given at fixed dose with no requirement for monitoring as pharm

The impact of pilot flame operation on the combustion of pure methane and hydrogen-enriched methane (H2/CH4: 50/50 in vol%) fuels was investigated in a gas turbine model combustor under atmospheric conditions. The burner assembly was designed to mimic the geometry of an industrial burner, the Siemens DLE Burner, in which a concentric annular ring equipped with pilot flame burners is implemented in

The number of patients on antithrombotic treatment due to atrial fibrillation and venous thromboembolism is increasing fast due to an aging population. A growing proportion will be treated with novel oral anticoagulants, the first in clinical use was the direct oral thrombin inhibitor dabigatran (Pradaxa®). A small percentage of the patients on dabigatran will experience serious bleeding or be in

PurposeNo consensus exists whether to administer prophylactic antibiotics in conjunction with manual placenta removal. This study aimed to investigate the postpartum risk of a new prescription of antibiotic treatment, a possible indirect variable for infection, after manual placenta removal.MethodsObstetric data were merged with data from the Anti-Infection Tool (Swedish antibiotic registry). All PurposeNo consensus exists whether to administer prophylactic antibiotics in conjunction with manual placenta removal. This study aimed to investigate the postpartum risk of a new prescription of antibiotic treatment, a possible indirect variable for infection, after manual placenta removal.MethodsObstetric data were merged with data from the Anti-Infection Tool (Swedish antibiotic registry). All

We use a unique source from the Swedish royal demesnes to examine the work and relative wages of women in sixteenth-century Sweden, an economic laggard in the early modern period. The source pertains to workers hired on yearly contracts, a type more representative of historical labour markets than day labour on large construction sites, and this allows us to observe directly the food consumed by w

Two novel Chlamydomonas-like species, belonging to the Moewusii clade, have been de-scribed. The first species inhabits eutrophic and neutral to basic pH waters in Sweden and England. It is easily recognizable under a light microscope due to its morphology (a small green prolate spheroidal shape with a large and truncated papilla at its anterior end, two equal flagella, a single lateral eyespot, a

Technological environments provide multiple conditions for the development of technology-based business and intellectual properties. Over the last decades, the Chilean government has designed/implemented a technology, innovation, and entrepreneurship policy framework. This chapter analyzes the technology transfer policy framework’s evolutionary process and its effectiveness. This chapter adopts a

Purpose: Type 1 diabetes is an autoimmune disease that often develops during childhood. Complications such as retinopathy often occur during the course of the disease. Studies to identify possible predictors of complications in type 1 diabetes are needed; in particular markers able to identify risk of complications long before they occur. The first aim of this study was to investigate plasma level

Reducing socioeconomic health inequalities is a key goal of most health systems. When care providers are paid prospectively, e.g., by a fixed sum per patient, existing inequalities may be sustained by the incentives to undertreat relatively unhealthy patients. To counter these incentives, prospective payments are often risk-adjusted based on observable patient characteristics. Despite that risk ad

I study how motivation shapes own and peers’ educational success. Using data from Project STAR, I find that academic motivation in early elementary school, as measured by a standardized psychological test, predicts contemporaneous and future test scores, high school GPA, and college-test taking over and above cognitive skills. Exploiting random assignment of students to classes, I find that exposu

The Siljan region hosts Europe´s largest impact structure. The high-relief landscape, with a central granite dome bordered by lake basins, contains an array of glacial and shore-level landforms. We investigated its deglaciation history by mapping and analysing landforms on high resolution LiDAR-based Digital Surface Models coupled with well-dated sediment successions from peat and lake sediment coThe Siljan region hosts Europe´s largest impact structure. The high-relief landscape, with a central granite dome bordered by lake basins, contains an array of glacial and shore-level landforms. We investigated its deglaciation history by mapping and analysing landforms on high resolution LiDAR-based Digital Surface Models coupled with well-dated sediment successions from peat and lake sediment co

Background: Previously, we investigated tonsillar carriage of Fusobacterium necrophorum by PCR and found a high tonsillar carriage rate (21%) in asymptomatic 15-25year olds, but the same age group is most commonly affected by severe F. necrophorum infections. Interestingly, we found Cycle threshold (Ct)-values in asymptomaticcarriers to be high (median 29). Possibly, the Ct-value could differentia

Att använda teori är en viktig del av historievetenskaperna. Med hjälp av teori kan en analys fördjupas och de empiriska resultaten göras greppbara i ett vidare sammanhang. För den som ska skriva en uppsats kan dock arbetet med teori framstå som abstrakt. Hur kan teorier bidra till historiska undersökningar? Hur arbetar man med teori – i praktiken? Det är temat i denna bok.Bokens kapitel tar avsta