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On the osmotic pressure of cells

The chemical potential of water (//h2o) provides an essential thermodynamic characterization of the environment of living organisms, and it is of equal significance as the temperature. For cells, //H,0 is conventionally expressed in terms of the osmotic pressure. We have previously suggested that the main contribution to the intracellular osmotic pressure of the bacterium E. coli is from soluble n

Assessment of phylogenetic approaches to study the timing of recombination cessation on sex chromosomes

The evolution of sex chromosomes is hypothesized to be punctuated by consecutive recombination cessation events, forming “evolutionary strata” that ceased to recombine at different time points. The demarcation of evolutionary strata is often assessed by estimates of the timing of recombination cessation (tRC) along the sex chromosomes, commonly inferred from the level of synonymous divergence or w

Short Attosecond Pulse Trains at High Repetition Rates for Novel Pump-Probe and Coincidence Studies

This work aims at studying photoionization dynamics from atoms and surfaces at attose time scales. The work was based on development and applications of a high repetition rate High-order Harmonic Generation (HHG) light source that utilizes Optical Parametric Amplification (OPA) laser technology. The laser system delivers few-cycle pulses in the near infrared (IR) at a repetition rate of 200 kHz. TThis work aims at studying photoionization dynamics from atoms and surfaces at attose time scales. The work was based on development and applications of a high repetition rate High-order Harmonic Generation (HHG) light source that utilizes Optical Parametric Amplification (OPA) laser technology. The laser system delivers few-cycle pulses in the near infrared (IR) at a repetition rate of 200 kHz. T

Taking Seat

The sound work "Taking Seat" by Robert Willim, could be experienced from a specially designed ‘sound bench’ placed outside Skissernas Museum in Lund. Combining manipulations of words and field recordings the work reflects practices of sitting.What are the forces set in motion by sitting? What are the technologies and techniques of sitting?Anthropologists argue that we have been living in The Sitti

Standardization, IPRs and open innovation in synthetic biology

It is fair to assume that the process of standardization may have a significant impact on the development and adoption of SB. Within SB different standardization efforts have been made, but none has assumed a dominance or authority in the area. Standardization efforts within SB may differ within various technical areas, and also the basic processes of standard creation can be divided into various

Energi- och resurseffektiva murade ytterväggar

EUs Energieffektiviseringsdirektiv innebär en skärpning av kraven på byggnaders energiprestanda. För murverksbranschens del har man identifierat ett behov av att utveckla ytterväggskonstruktioner med 30 procent lägre U-värde jämfört med idag vanligt förekommande murade ytterväggslösningar. Utveckling av välisolerade murade ytterväggskonstruktioner med tunna, ytförstärkta bärande delar förefaller v

Sexual Harassment and Criminalisation

The aim of this paper is to explore sexual harassment and criminalisation, and, more specifically, to what extent the criminal legal system may serve as a measure against sexual harassment. It is not the task of this paper to provide a straightforward answer. Instead, it provides abrief account of ongoing trends in Sweden which prompts further analysis of this issue, suchas #metoo, crime statistic

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders

The contribution of the epicardium, the outermost layer of the heart, to cardiac regeneration has remained controversial due to a lack of suitable analytical tools. By combining genetic marker-independent lineage-tracing strategies with transcriptional profiling and loss-of-function methods, we report here that the epicardium of the highly regenerative salamander species Pleurodeles waltl has an i

Interplay between Caveolin-1 and body and tumor size affects clinical outcomes in breast cancer

BACKGROUND: Caveolin-1 (CAV1) is associated with cholesterol-rich membrane raft domains and is a master regulator of cell signaling and membrane transport. Here, we investigated CAV1's role in cellular compartments of breast cancer in relation to signaling pathways, clinicopathological features, and clinical outcomes.METHODS: CAV1 levels were evaluated with immunohistochemistry in cytoplasm of inv

The Integrated Use of Dendrochronological Data and Paleoecological Records From Northwest European Peatlands and Lakes for Understanding Long-Term Ecological and Climatic Changes—A Review

Our overall understanding of long-term climate dynamics is largely based on proxy data generated from archives such as ice cores, ocean sediments, tree rings, speleothems, and corals, whereas reconstructions of long-term changes in vegetation and associated climate during the Holocene are largely based on paleoecological records from peat and lake sequences, primarily pollen and plant macrofossil

Progress towards controlling the HIV epidemic in urban Ethiopia : Findings from the 2017–2018 Ethiopia population-based HIV impact assessment survey

Introduction In 2014, the Joint United Nations Programme on HIV/AIDS set an ‘ambitious’ 90-90-90 target for 2020. By 2016, there were disparities observed among countries in their progress towards the targets and some believed the targets were not achievable. In this report, we present the results of data from the Ethiopia Population-based HIV Impact Assessment survey analyzed to assess progress w

Collegiality and efficiency in bureaucracy

This article addresses the relation between the design of regulatory agencies and efficiency, arguing that authority concentrated to a single individual outperforms more collegial decision-making when the regulated firms’ interests are aligned. The tentative explanation is that concentrated leadership reduces the risk for capture. This argument is developed from an empirical case on the markets fo

Lipid bilayer composition as a determinant of cancer cell sensitivity to tumoricidal protein-lipid complexes

Complexes formed by the alpha1 N-terminal peptide of alpha-lactalbumin and oleic acid (alpha1-oleate) interact with lipid bilayers. Plasma membrane perturbations trigger tumor cell death but normal differentiated cells are more resistant, and their plasma membranes are less strongly affected. This study examined membrane lipid composition as a determinant of tumor cell reactivity. Bladder cancer t