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Frequent emergence of resistance in Clostridium difficile during treatment of C-difficile-associated diarrhea with Fusidic acid

Samples from patients with Clostridium difficile-associated diarrhea (CDAD) that were randomized to fusidic acid (n = 59) or metronidazole (n = 55) therapy for 7 days were cultured for Clostridium difficile in feces on days 1, 8 to 13, and 35 to 40. Of the patients who were culture positive only before treatment, 77% (36/47) were permanently cured (no treatment failure and no clinical recurrence),

Thermal bridges : a non-computerized calculation procedure

This study presents a non-computerized calculation procedure for steady state two-dimensional conductive heat losses through thermal bridges. The heat flow is divided into distinct flow paths based on physical considerations. A resistance is derived analytically for each flow path. These resistances are combined into a net work. The network simulates the construction. Calculating the total resista

Centrum. Utarmning eller renässans?

Centrums roll och funktion har förändrats över tiden under perioder av urbanisering, suburbanisering, desurbanisering och reurbanisering. Transportmedelsutvecklingen och olika stadsplaneringstraditioner har påverkat såväl stadsstrukturen som centrums uppbyggnad. Det övergripande syftet med boken är att belysa hur olika bebyggelse- och trafikmässiga faktorer samverkar och formar centrum och centrum

Positioneringsfraser i interaktion. Syntax, prosodi och funktion.

This thesis is an empirical study of how positioning is achieved in interactional Swedish. Positioning has previously been described in terms of epistemic modality, interpersonal positioning, stanceand speech act adverbials. The aims of the study are, firstly, to identify what linguistic resources are used to achieve positioning in interaction. A second aim is to describe where in the turn-con

Applications of the Complex Modulation Transfer Function on SEA-systems

The SEA coupling and dissipation loss factors are determined in-situ from Complex Modulation Transfer Functions, CMTF:s, based on measured impulse-responses. A quotient of CMTF:s is least-square curve-fitted to a SEA model and the SEA loss factors are determined from the results of the curve-fit. A two subsystem SEA model with time-varying power is considered. In the frequency domain, power-energ

Intrauterine exposure to maternal enterovirus infection as a risk factor for development of autoimmune thyroiditis during childhood and adolescence.

Maternal intrauterine enterovirus infection during pregnancy increases the risk for the offspring to develop type 1 diabetes mellitus. Type 1 diabetes mellitus and autoimmune thyroiditits (AIT) are closely linked. A common pathogenetic factor is possible. The objective of this study was to investigate a possible association between maternal enterovirus infection during pregnancy and the developmen

Högpresterande betong

Under sex år har väsentliga egenskaper hos den nya så kallade högpresterande betongen studerats av svenska forskare i samverkan med ett antal företag i byggbranschen. Möjligheter och potentiella risker med det nya materialet har klarlagts. Den högpresterande betongen ger stora möjligheter till konstruktioner med högre prestanda och möjliggör mera rationella produktionsmetoder. Det ankommer nu i fö

Increased risk of acute myocardial infarction and elevated levels of C-reactive protein in carriersof the Thr-87 variant of the ATP receptor P2Y11.

Aims Extracellular ATP acting on the P2Y(11) receptor regulates inflammatory cells. We hypothesized that polymorphisms in the receptor could influence the risk of acute myocardial infarction (AMI). Methods and results In the Malmo diet and cancer AMI case-control study (n = 3732) the P2Y(11) gene Thr-87 polymorphism was present in 19.8% of the controls and 22.9% in AMI patients (OR 1.21; P = 0.03)

Upper gastrointestinal trauma. Analysis of 45 cases of gastric, duodenal or pancreatic injury

Injuries to the upper gastrointestinal tract occurring over a 30-year period in a geographically well defined region were analyzed. The incidence was low in comparison with other abdominal injuries, but duodenal and pancreatic injuries were increasingly common in the study's last decade. The stomach injuries were mainly caused by penetrating trauma. The duodenal and pancreatic injuries most common

Synthesis of a Ru(bpy)(3)-type complex linked to a free terpyridine ligand and its use for preparation of polynuclear bimetallic complexes

A terpyridine ligand has been covalently linked to a Ru(bpy)(3) complex via an amide bond. By using this functionalized terpyridine ligand, a series of multinuclear bimetallic complexes have been synthesized and characterized. One of these complexes has the structure of di-mu-oxobridged Mn dimer. EPR spectra of this complex showed that, depending on the procedure for the preparation, the oxidation

ML estimation of time and frequency offset in OFDM systems

We present the joint maximum likelihood (ML) symbol-time and carrier-frequency offset estimator in orthogonal frequency-division multiplexing (OFDM) systems. Redundant information contained within the cyclic prefix enables this estimation without additional pilots. Simulations show that the frequency estimator may be used in a tracking mode and the time estimator in an acquisition mode.

Combined binary ratio labeling fluorescence in situ hybridization analysis of chordoma

Chordoma is a rare, low- to intermediate-grade malignant tumor involving the axial spine. Cytogenetic data on these tumors have been limited to 25 cases. The findings of clonal chromosome aberrations in five new cases are presented. One of these and two previously reported cases have been studied with multicolor combined binary ratio labeling fluorescence in situ hybridization (COBRA-FISH). The ka