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Lower circulating mitochondrial DNA and increased mitokines suggest significant mitochondrial dysfunction in systemic lupus erythematosus with renal involvement

BACKGROUND: SLE is associated with significant morbidity, especially in the case of renal involvement. Mitochondrial dysfunction plays a significant role in SLE and may be assessed by measuring mitochondrial DNA (mtDNA) and cytokines reflecting mitochondrial stress (mitokines). Circulating mtDNA is a promising biomarker in SLE and appears to be reduced in severe SLE. However, measuring circulating

Preeclampsia from a Patient Perspective

Background: Preeclampsia is a leading cause of maternal and fetal mortality. Although antenatal care can identify women at risk, limited research has explored women's experiences with preeclampsia despite itssignificant impact.Aim: This thesis aims to enhance the understanding of women's experiences with preeclampsia in order toimprove clinical care, support, and mental health outcomes. This inclu

EXTRAPOLATION ON HARDY SPACES AND APPLICATIONS

In this survey article some classical results concerning real interpolation between Hardy spaces are briefly presented and then it is explained how those results can be used to establish Yano-type extrapolation theorems for Hardy spaces. Some new extensions and variants of certain classical endpoint theorems in harmonic analysis are obtained as applications of the extrapolation results presented h

Event Segmentation in Audio Description Reception: Impacts on Media Access, Inclusion, and Computer-Generated Description

Audio description (AD) serves a critical role in making audio-visual media accessible to visually impaired audiences, aiming to enhance their viewing experience and comprehension (Holsanova 2016, 2022). A central inquiry in the context of successful AD pertains to how the sequence of events unfolding in a film aligns with the verbal narration conveyed through AD (Vandaele 2012). Accumulating resea

Making Sense without Meaning : Christopher Alexander and the Automation of Design

In his contribution to the infuential “Architecture and the Computer”conference in 1964, Christopher Alexander summarised the reorganisation of intellectual labour that, beginning in the 19th century,became fnally concretised in the technologies of the computer. Inhis opinion, computers should be regarded as nothing else than hugearmies of clerks, stupid and without initiative, but able to follow

Ett nytt Öresundsavtal – En modell för hybridarbete i Norden

Det uppdaterade Öresundsavtalet mellan Sverige och Danmark markerar en modernisering av det tidigare avtalets regler i en tid präglad av förändrade arbetsmönster. Avtalet, som inkluderar både privat- och offentliganställda, syftar till att förenkla beskattning för gränspendlare och arbetsgivare. Tillsammans med Öresundsöverenskommelsen som reglerar socialförsäkringstillhörighet förläggs beskattnin

Effect of broccoli sprout extract and baseline gut microbiota on fasting blood glucose in prediabetes : a randomized, placebo-controlled trial

More effective treatments are needed for impaired fasting glucose or glucose intolerance, known as prediabetes. Sulforaphane is an isothiocyanate that reduces hepatic gluconeogenesis in individuals with type 2 diabetes and is well tolerated when provided as a broccoli sprout extract (BSE). Here we report a randomized, double-blind, placebo-controlled trial in which drug-naive individuals with pred

Floristic Legacy of English-Style Landscape Gardens and the Use of Imported Grass Seed for Sowing under Trees

During WWII, the botanist Hylander (1943, 1949) studied the floristic composition of lawns in 249 landscape gardens mostly in Sweden and concluded that they all harboured multiple, but largely the same, non-native species and genotypes that had most likely been introduced together by the sowing of some im- ported grass seed mix. As demonstrated by the later additions by, for example, Ohlsén (1947)During WWII, the botanist Hylander (1943, 1949) studied the floristic composition of lawns in 249 landscape gardens mostly in Sweden and concluded that they all harboured multiple, but largely the same, non-native species and genotypes that had most likely been introduced together by the sowing of some im- ported grass seed mix. As demonstrated by the later additions by, for example, Ohlsén (1947)