Sökresultat

Filtyp

Din sökning på "*" gav 530420 sökträffar

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)

α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985. A1M is described as an antioxidant and tissue cleaning protein with reductase, heme- and radical-binding activities. These biochemical properties are driven by a strongly electronega

Computational methods for querying and sampling the Twitter disinformation datasets

This study attempts to apply computational methods to the Twitter Election Integrity Datasets in order to derive a basic descriptive overview of this disinformation data, and to suggest some possible routes for developing these methods to address future research questions. The results indicate substantial variations in tweet frequency over time and geographical regions, as well as differences in r

Adipocytes Under Obese-Like Conditions Change Cell Cycle Distribution and Phosphorylation Profiles of Breast Cancer Cells : The Adipokine Receptor CAP1 Matters

Background: Obesity and associated metabolic conditions impact adipocyte functionality with potential consequences for breast cancer risk and prognosis, but contributing mechanisms remain to be understood. The adipokine receptor adenylyl cyclase-associated protein-1 (CAP1) has been implicated in the progression of breast cancer, but results are conflicting and the underlying molecular mechanisms a

Life satisfaction and adaptation in persons with Parkinson’s disease — A qualitative study

Persons with Parkinson’s disease (PD) need to adapt to their progressive disability to achieve and maintain a high degree of life satisfaction (LS), but little is known about the meaning of LS and adaptation. This study aimed to gain an in-depth understanding of the meaning of LS and adaptation in persons with PD. Open-ended in-depth interviews were performed with 13 persons diagnosed with PD, 9 w

The effect of nitrogen fertilization on tree growth, soil organic carbon and nitrogen leaching—a modeling study in a steep nitrogen deposition gradient in Sweden

Nitrogen (N) fertilization in forests has the potential to increase tree growth and carbon (C) sequestration, but it also means a risk of N leaching. Dynamic models can, if the important processes are well described, play an important role in assessing benefits and risks of nitrogen fertili-zation. The aim of this study was to test if the ForSAFE model is able to simulate correctly the effects of

Water quality changes during the first meter of managed aquifer recharge

The capacity of an artificial recharge field to alter organic matter and the bacterial flora of surface water was assessed by following changes in bacterial communities and composition of natural organic matter (NOM) over the first meter of infiltration depth. The sampling strategy applied in this study ensured that water samples consisted only of infiltrated water, excluding natural groundwater.

Moths are strongly attracted to ultraviolet and blue radiation

We carried out three choice experiments with 6116 nocturnal lepidopteran individuals (95 species, 7 families, 32 075 counts), each replicated 105 times during the seasons of 2 years. Moths were released indoors at the centre of a 10 × 10 m area with different lamps placed at each corner. In experiment 1, lamps emitted ultraviolet (UV) (peak at 365 nm), blue (450 nm), green (520 nm) or cool white (

Biomechanical properties of common carotid arteries assessed by circumferential 2D strain and β stiffness index in patients with ankylosing spondylitis

Objective. Ankylosing spondylitis (AS) is associated with an elevated risk of cardiovascular disease (CVD) related to atherosclerosis, preceded by arterial stiffness. We aimed to examine common carotid artery (CCA) biomechanical properties using ultrasound to calculate β stiffness index (indicating arterial stiffness) and, a more recently developed technique, 2-dimensional (2D) speckle tracking st

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

The overall goal of this article is to demonstrate a state-of-the-art ultrahigh field (UHF) magnetic resonance (MR) protocol of the brain at 7.0 Tesla in multiple sclerosis (MS) patients. MS is a chronic inflammatory, demyelinating, neurodegenerative disease that is characterized by white and gray matter lesions. Detection of spatially and temporally disseminated T2-hyperintense lesions by the use

Erövringen : Muslimska brödraskapets infiltration av Sverige

Hur mycket naivitet har präglat svenska politiska partier då de trott att de skulle kunna omvända islamister till demokrater och inkludera dem i det sekulära mångkulturella samhället? Hur mycket naivitet har präglat islamister att tro att de skulle kunna erövra Sverige med infiltration inifrån? Kan islamister förvandlas till demokrater samtidigt som de är textbundna till en fundamentalistisk tolkn

Ablation of Aquaporin-9 Ameliorates the Systemic Inflammatory Response of LPS-Induced Endotoxic Shock in Mouse

Septic shock is the most severe complication of sepsis, being characterized by a systemic inflammatory response following bacterial infection, leading to multiple organ failure and dramatically high mortality. Aquaporin-9 (AQP9), a membrane channel protein mainly expressed in hepatocytes and leukocytes, has been recently associated with inflammatory and infectious responses, thus triggering strong

Dental care of patients exposed to sexual abuse : Need for alliance between staff and patients

The aim was to explore the experiences of sexually abused individuals as dental patients. Purposively selected were 13 informants (11 women) aged 19–56. All had experienced sexual abuse as children or adults and memories of this abuse had been triggered and expressed during a dental appointment. They were encouraged to relate in their own words their experiences of the dental appointment. The inte

Preoperative sleep quality and adverse pain outcomes after total hip arthroplasty

Background: Sleep disturbance is thought to aggravate acute postoperative pain. The influence of preoperative sleep problems on pain control in the long-term and development of chronic postsurgical pain is largely unknown. Methods: This prospective, observational study aimed to examine the links between preoperative sleep disturbance (Pittsburgh Sleep Quality Index, PSQI) and pain severity (Brief

No title

Critique of immigration researchers who use Danish racism or whiteness to explain all immigrant problems, or refuse to discuss problems such as social control, domestic violence, honor-shame violence, criminality, radicalization, social marginalization, etc. Not all immigrant problems are caused by racism. Antiracist researchers need more courage.

Time dependence in diffusion MRI predicts tissue outcome in ischemic stroke patients

Purpose: Reperfusion therapy enables effective treatment of ischemic stroke presenting within 4–6 hours. However, tissue progression from ischemia to infarction is variable, and some patients benefit from treatment up until 24 hours. Improved imaging techniques are needed to identify these patients. Here, it was hypothesized that time dependence in diffusion MRI may predict tissue outcome in ische

Isolation and Characterization of Shiga Toxin-Associated Microvesicles

Microvesicles are shed from cell surfaces during infectious or inflammatory conditions and may contribute to the pathogenesis of disease. During Shiga toxin-producing Escherichia coli (STEC) infection, microvesicles are released from blood cells. These microvesicles play a part in inflammation, thrombosis, hemolysis, and the transfer of the main virulence factor of STEC strains, Shiga toxin, to ta

Corona in Denmark: Germans in, Swedes out…

Describes rise of Danish nationalism during early Covid19. Danish summer house operators in Jutland want the German tourisets to come. The government wants the Swedes to stay out because they are too relaxed about Covid.