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Review of: C. L. Westphahl. A Discourse Analysis of the Letter to the Hebrews. The Relationship between Form and Meaning (Library of NT Studies, 297), T & T Clark Intern. London – New York. 339 pp

Westphal's thesis contains a summary of earlier structural analyses of Hebrews. Her own discourse analysis structures Hebrews into three parts 1) 1:1–4:16; 2) 4:11–7:28 and 8:1–10:25; 3) 10:19–13:25. Westphal characterizes Heb 4:11-16 and 10:19-25 as "overlapping" parts and as keys to the structure and meaning of Hebrews. The structure according to this approach is not new. A shortcoming in this t

Using Conceptual Spaces to Model Actions and Events

Actions and events are central to a semantics of natural language. In this article, we present a cognitively based model of these notions. After giving a general presentation of the theory of conceptual spaces, we explain how the analysis of perceptual concepts can be extended to actions and events. First, we argue that action space can be analyzed in the same way as, for example, colour space or

Altering the laccase functionality by in vivo assembly of mutant libraries with different mutational spectra

The generation of diversity for directed protein evolution experiments shows an important bottleneck in the in vitro random mutagenesis protocols. Most Of them are biased towards specific changes that eventually confer a predicted and conservative mutational spectrum, limiting the exploration of the vast protein space. The current work describes a simple methodology to in vivo recombine mutant lib

Specialized pediatric healthcare with limited resources: Surgery, anesthesia and oncology for children in low- and middle-income countries

Aim: This thesis serves two purposes. First, it informs specialists in global public health to consider a broader spectrum of pediatric disease. Second, it informs specialists in pediatric hospital care of how the feasibility of their clinical practice depends on a functioning health care system. Methods: The papers contextualize pediatric disease entities that so far have received relatively sp

Physics based on electron beam ion traps

A brief description of the operational principles of an Electron Beam Ion Trap is given with specific reference to the currently under development/construction Shanghai EBIT. This is followed by an introduction to some of the frontier physics problems of highly charged ions that can be studied with such devices. Also a discussion of the use of EBITs as a powerful tool in hot-plasma diagnostics is

Accurate QM/MM free energy calculations of enzyme reactions: Methylation by catechol O-methyltransferase

We recently described a method to compute accurate quantum mechanical free energies [Rod, T. H.; Ryde, U. Phys. Rev. Lett. 2005, 94, `138302]. The method, which we term quantum mechanical thermodynamic cycle perturbation (QTCP), employs a molecular mechanics force field to sample phase space and, subsequently, a thermodynamic cycle to estimate QM/MM free energy changes. Here, we discuss the method

Effect of feed supplementation with phytohaemagglutinin in combination with alpha-ketoglutarate on growth and nitrogen elimination pathways in rats with acute renal failure induced by nephrectomy

Introduction: Phytohaemagglutinin (PHA) and alpha-ketoglutaric acid (AKG) in growing rats stimulate a change in the proportion of N excretion via urine and faeces, in favour of faecal excretion. The aim of the study was to investigate the effect of oral supplementation of PHA and AKG on pathways of nitrogen excretion and serum levels of urea in uraemic conditions induced by nephrectomy. Material a

Band Crossing Phenomena in N = Z Nuclei - A Probe to T=0 Pairing Correlations?

The structure of the N = Z nuclei Zn-60, Ga-62, Ge-64 and Kr-72 has been investigated at GASP. Total Routhian surface (TRS) calculations have been performed for the N = 36, 38 and 40 Kr isotones. In the case of Kr-72 the four quasi-particle g(9/2) alignment is observed to be significantly delayed in rotational frequency with respect to the heavier Kr isotopes. Such a delay contradicts the predicti

Cramer-Rao lower bounds for inverse scattering problems of multilayer structures

In this paper, the inverse scattering problem of amultilayer structure is analysed with the Fisher information matrix and the Cramer-Rao lower bound (CRLB). The CRLB quantifies the ill-posedness of the inverse scattering problem in terms of resolution versus estimation accuracy based on the observation of noisy data. The limit for feasible inversion is identified by an asymptotic eigenvalue analys

Monte Carlo study of TLD measurements in air cavities

Thermoluminescent dosimeters (TLDs) are used for verification of the delivered dose during IMRT treatment of head and neck carcinomas. The TLDs are put into a plastic tube, which is placed in the nasal cavities through the treated volume. In this study, the dose distribution to a phantom having a cylindrical air cavity containing a tube was calculated by Monte Carlo methods and the results were co

Deposition of HfO2 on InAs by atomic-layer deposition

Metal-oxide-semiconductor (MOS) capacitors are formed on bulk InAs substrates by atomic-layer deposition (ALD) of HfO2. Prior to film growth, InAs substrates receive a wet-chemical treatment of HCl, buffered HF (BHF), or (NH4)(2)S. Hafnium dioxide films are grown using 75 ALD cycles with substrate temperatures of 100, 200, and 300 degrees C. Substrate temperature is found to have a significant inf

Dynamics of FtsZ assembly during sporulation in Streptomyces coelicolor A3(2)

FtsZ, the bacterial tubulin homologue, is the main player in at least two distinct processes of cell division during the development of Streptomyces coelicolor A3(2). It forms cytokinetic rings and is required for the formation of both the widely spaced hyphal cross walls in the substrate mycelium and the specialized septation that converts sporogenic aerial hyphae into spores. The latter developm

Solar activity during the last 1000 yr inferred from radionuclide records

Identification of the causes of past climate change requires detailed knowledge of one of the most important natural factors—solar forcing. Prior to the period of direct solar observations, radionuclide abundances in natural archives provide the best-known proxies for changes in solar activity. Here we present two independent reconstructions of changes in solar activity during the last 1000 yr, wh

Neutralizing activity and cellular immune responses induced in mice after immunization with apoptotic HIV-1/murine leukemia virus infected cells

Dendritic cells present microbial antigens to T cells after uptake of apoptotic vesicles from infected cells. We previously reported that immunizations with apoptotic HIV-1/murine leukemia virus (MuLV) infected cells lead to induction of both cellular and humoral immune responses as well as resistance to mucosal challenge with live HIV-1/MuLV infected cells. Here we extended those studies and inve

Palaeomagnetism of Mesoproterozoic dykes from the Protogine Zone, southern Sweden and the enigmatic Sveconorwegian Loop

A palaeomagnetic study of samples from dykes in the Protogine Zone (PZ) south of Lake Vattern has yielded two characteristic magnetic components, A and B. A comparison with previous data and the Sveconorwegian Loop of the Fennoscandian Apparent Polar Wander Path (APWP) make it possible to estimate the age of the corresponding palaeomagnetic poles. They are situated close to the "Loop", which indic

Results of the first WHO international collaborative study on the standardization of the detection of antibodies to human papillomaviruses

Detection of genotype-specific human papillomavirus (HPV) capsid antibody in serum suggests past HPV infection. Also, these antibodies appear to correlate with vaccine-induced protection against infection, at least in animal models. However, each laboratory defines a reactive result differently and there is no agreed definition of what level of response indicates sero-reactivity. Standardization o