In most control schemes it is advantageous to introduce integrators to eliminate off-set due to load disturbances. It is, however, also important to introduce nonlinearities, for instance due to limitations in actuators. The interaction between the integrator and the nonlinearities will cause problems with reset windup. Ways to handle anti-reset windup for different controller configurations are d

This paper discusses some problems that can arise in distributed real-time control systems, for instance, sampling- interval jitter, timeout, and asynchronous loops.

BACKGROUND: Recent advances in disease-modifying treatments highlight the need for accurately identifying individuals in early Alzheimer's disease (AD) stages and for monitoring of treatment effects. Plasma measurements of phosphorylated tau (p-tau) are a promising biomarker for AD, but different assays show varying diagnostic and prognostic accuracies. The objective of this study was to determine

Freshwater ecosystems are under multiple threats in modern times such as water extraction for human consumption, industries and agricultural activities, water contamination and habitat destruction for example. At the same time the biodiversity of these ecosystems are often poorly studied, especially in arid countries such as Iran. In this work, we study one of the ecologically important members of

COVID-19-pandemins första våg präglades av stor osäkerhet kring den nya sjukdomen och experter världen mobiliserade för att kartlägga den nya sjukdomen, hastigheten i dess spridning och dess dödlighet. På grund av dessa osäkerheter blev epidemiologiska modeller en viktig resurs i arbetet med att bemöta och hantera pandemin. Genom att modellera dess troliga förlopp och påverkan skapade epidemiologi

According to religious fictionalism, a non-believer can participate in religious life by playing a game of make-believe. Considering how games of make-believe build on imagination and pretence, I argue that religious fictionalism requires the non-believing participant to engage in role-playing. Turning to the literature on role-playing games, I demonstrate how religious fictionalism conforms to a

The thesis studies a European Union legal form for organisation from the perspective of EU law and Swedish law on associations (associationsrätt). The legal form in focus is the European Research Infrastructure Consortium (ERIC), which was introduced by Council Regulation (EC) No 723/2009 of 25 June 2009 (the ERIC Regulation). The ERIC legal form allows states and intergovernmental organisations t

The New Horizons flyby of the cold classical Kuiper Belt object MU69 showed it to be a contact binary. The existence of other contact binaries in the 1–10 km range raises the question of how common these bodies are and how they evolved into contact. Here we consider that the pre-contact lobes of MU69 formed as a binary embedded in the Solar nebula, and calculate its subsequent orbital evolution in

The data that is currently used when designing egress systems for stadia and other high-occupancy buildings was collected decades ago and might not be applicable in today's society. A systematic analysis of crowd movement was performed to investigate egress flows at a large stadium in the UK following four different event types (i.e., a football game, a rugby game, a concert featuring a male singe

Background: Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim: To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method: A case study based on an anthropological field study amongBackground:Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim:To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method:A case study based on an anthropological field study among pa

Culture conditions in which hematopoietic stem cells (HSCs) can be expanded for clinical benefit are highly sought after. Here, we report that inhibition of the epigenetic regulator Lysine-specific histone demethylase 1A (LSD1) induces a rapid expansion of human cord blood derived CD34+ cells and promotes in vitro propagation of long-term repopulating HSCs by preventing differentiation. The phenot

We report on the use of a sacrificial AlAs segment to enable substrate reuse for nanowire synthesis. A silicon nitride template was deposited on a p-type GaAs substrate. Then a pattern was transferred to the substrate by nanoimprint lithography and reactive ion etching. Thermal evaporation was used to define Au seed particles. Metalorganic vapour phase epitaxy was used to grow AlAs-GaAs NWs in the

Objectives: This study aimed to investigate the occurrence of suicidal ideation and associated factors in older persons with dementia living at home in eight European countries, and its association with quality of life. Furthermore, changes in suicidal ideation over time were investigated. Methods: This cohort study (n = 1,223) was part of the European “RightTimePlaceCare” project conducted in 201

The concepts ‘rural’ and ‘urban’ have long been criticized by geographers for their lack of analytical and explanatory power, yet have remained a vital source for conceptual guidance in human geography. Realizing that the continued use of questionable concepts inadvertently runs the risk of compromising communication, misdirecting resources and downgrading social theory, the current status of ‘rur

Poverty and social exclusion remain some of the biggest concerns in the face of obtaining social sustainability. In this respect, the continuing immense spatial differences between individual localities of seemingly similar characteristics have puzzled social scientists for decades. In quest for a better understanding, this article highlights the role of spatial heterogeneity as a factor conducive

In thin notched sheets under tensile loading, wrinkling appears on the sheet surface, specifically around the cracked area. This is due to local buckling and compression stresses near the crack surfaces. This study aims to numerically study the buckling behavior of a thin sheet with a central crack under tension. A numerical model of a notched sheet under tensile loading is developed using the fin

A key enabler for Industry 4.0 is Fifth Generation Wireless Specifications (5G), within which network slicing is a promising technique to ensure customized quality of service for specific end-user groups in industrial scenarios. Massive Multiple Input Multiple Output (MIMO) plays a significant role in 5G but network slicing for massive MIMO has not yet been addressed. In this paper, we propose a n

The partially premixed combustion (PPC) concept is regarded as an intermediate process between the thoroughly mixed Homogeneous charge compression ignition (HCCI) combustion and compression ignition (CI) combustion. It's a combination of auto-ignition mode, a fuel-rich premixed combustion mode, and a diffusion combustion mode. The concept has both high efficiency and low soot emission due to low h

Background: Diet is a determinant of gut microbiota. Both diet and gut microbiota have been linked to metabolic diseases. Objective: We aimed to examine data-driven food patterns in relation to the prevalence of prediabetes and gut microbiota composition and food pattern-associated bacteria in relation to prediabetes. Methods: Food patterns were extracted using principal component analysis in 1726

Partially premixed combustion (PPC) is an advanced combustion concept and powertrain technology, which has a great potential to improve the fuel economy of vehicles. The process of PPC is driven by both chemical kinetics and mixing process, and is, therefore, sensitive to inlet conditions and injection process. This article presents a control-oriented combustion and air-path model of a PPC multicy