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Adding realism to simulated sensors and actuators.

In this paper, we propose a statistical theoretical framework for incorporation of sensor and actuator faults in dynamic simulations of wastewater treatment operation. Sensor and actuator faults and failures are often neglected in simulations for control strategy development and testing, although it is well known that they represent a significant obstacle for realising control at full-scale facili

Atrioventricular nodal function during atrial fibrillation: Model building and robust estimation

Statistical modeling of atrioventricular (AV) nodal function during atrial fibrillation (AF) is revisited for the purpose of defining model properties and improving parameter estimation. The characterization of AV nodal pathways is made more detailed and the number of pathways is now determined by the Bayesian information criterion, rather than just producing a probability as was previously done.

Managing the needs of end-users in the design and delivery of construction projects

Purpose – The two-fold purpose of this paper is identifying areas of difficulty in managing the needs of end-users in the course of the design and delivery of construction projects and suggesting possible solutions. Design/methodology/approach – The focus of the paper is the interaction between three principal parties: end-users, project leader (a selected end-user) and facility planner (a facil

Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections

Chronic granulomatous disease (CGD) is an inherited disorder characterized by recurrent life-threatening bacterial and fungal infections. CGD results from defective production of reactive oxygen species by phagocytes caused by mutations in genes encoding the NADPH oxidase 2 (NOX2) complex subunits. Mice with a spontaneous mutation in Ncf1, which encodes the NCF1 (p47(Phox)) subunit of NOX2, have d

Clinical And Experimental Studies of Contact Allergy to Stent Metals - with focus on gold

Popular Abstract in Swedish I det här arbetet studerades kontaktallergi för metaller som finns i olika stentar. Patienterna som ingick i studien hade blivit stentade med olika typer av stentar. En av stentarna var gjord av rostfritt stål (nickelstent) och den andra var förgylld (guldstent). Resultaten av lapptestningen visade att patienterna hade en hög frekvens av både guld- och nickelallergi, ocA large number of patients are treated with coronary stents, and restenosis (recurrent narrowing of the vessel) is a serious problem. Contact allergy to metal ions eluted from stainless steel stents has been suggested to contribute to in-stent restenosis. Studies have reported a higher rate of restenosis with gold-plated stents, but the correlation to contact allergy was not evaluated. Nickel is t

The role of the deubiquitinating enzyme CYLD and its substrate BCL-3 in solid tumors

The tumor suppressor CYLD and the proto-oncogene BCL-3 are known to be deregulated in various cancer types. The molecular background of how these genes participate in carcinogenesis is not fully understood. CYLD is a deubiquitinating enzyme known to specifically target lysine 63 linked ubiquitin chains, which can negatively regulate the BCL-3, NF-κB and JNK signaling pathways, leading to a decreas

Analysis of brain and muscle activity during low-level tooth clenching - a feasibility study with a novel biting device

In electromyographic (EMG) and functional magnetic resonance imaging (fMRI) studies, muscle and brain activity was compared during low levels of tooth clenching using a novel biting device to control bite force. A total of 21 healthy subjects performed motor tasks, comprising tooth clenching at 5, 10 and 20N. During all measurements, subjects kept the novel bite device between the anterior teeth d

The absorption, tissue distribution and excretion of enteraly administered alpha-ketoglutarate in rats.

The absorption, tissue distribution and excretion of enteral alpha-ketoglutarate (AKG) was studied in four experiments. Six male Sprague Dawley rats were used to investigate the excretion of AKG in urine and faeces. Thirty rats, randomly assigned to five groups, were used to investigate the distribution of AKG in body tissues. They were gavaged with AKG enriched with 3 muCi/kg BW of (14)C uniforml

A provoking choice-Swedish women's experiences of reactions to their plans to give birth at home

Objective: The home birth rate in Sweden is less than 1 in 1000, and home birth is not included within the health care system. This study describes women's experiences concerning reactions to their decision to give birth at home. Design and setting: A nationwide survey (SHE - Swedish Homebirth Experience) in Sweden was conducted between 1992 and 2005 whereas 735 women had given birth to 1038 child

Researching Public Libraries and the Social Web, 2006-2012

Purpose: The purpose of this paper is to sketch out the general tendencies, gaps, and opportunities within the body of research studying the social web as a new facet of public librarianship in order to delineate the findings so far and suggest directions for future research. Study design: Literature searches were conducted through the LISTA database, The ISI Web of Science database and The Direct

Key Features of the TMD Soft-Factor Structure

We show that the geometry of the Wilson lines, entering the operator definition of the transverse-momentum dependent parton distributions and that of the soft factor, follows from the kinematics of the underlying physical process in conjunction with the gauge invariance of the QCD Lagrangian. We demonstrate our method in terms of concrete examples and determine the paths of the associated Wilson l

Competition enhances spatial genetic differentiation

Questions: How does the number of species in a community affect the level of genetic diversity of its constituent species? What is the relation between competitive interactions and the spatial distribution of genetic variation? When spatially structured, how is the genetic differentiation among subpopulations affected by competition and size of the community? Model features and key assumptions: A

Retrofitting of reinforced concrete beams using composite laminates

This paper presents the results of an experimental study to investigate the behaviour of structurally damaged full-scale reinforced concrete beams retrofitted with CFRP laminates in shear or in flexure. The main variables considered were the internal reinforcement ratio, position of retrofitting and the length of CFRP. The experimental results, generally, indicate that beams retrofitted in shear a

Comparison of Cis- and Oxaliplatin-induced Destabilization of 15-mer DNA- and RNA Duplexes by Binding to Centrally Located GG- and GNG Sequences

Thermodynamic parameters are presented here illustrating the effects caused by the two anticancer active metal complexes cisplatin and oxaliplatin after introduction into four closely related RNA and DNA duplexes. The duplexes used are blunt end, fully complementary 15-mer duplexes with a centrally located either GG- or GNG (here: N = T or U) binding site. For all duplexes, a common trend of reduc