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An important question for video game research is how to characterize the video game experience. One common view emphasizes that players are cognitively able to operate with the game world as the experiential point of reference leading to states of "immersion, "spatial presence", or "engagement". A different view is that the player is also embodied and situated in the actual world, entailing that t
A thermodynamically consistent model for porous cellulose networks is proposed. A general theory is developed based on mixture theory using chemical potentials as flow potentials. The material is decomposed into three phases, solid, liquid and gas, where the solid and gas phases are further separated into dry fiber and fiber water, water vapor and dry air, respectively. Between the phases interfac
Hypothalamus (HT) is a brain structure which serves as a coordination center for several vital body functions. Craniopharyngioma (CP) is a pituitary tumor with high morbidity, primarily due to HT lesion. Among important consequences of CP are cognitive dysfunction and intractable weight gain due to HT obesity, resulting in high cardiovascular (CV) risk. A better understanding of the structural bra
Motivated by the recent development of fast and ultrasensitive thermometry in nanoscale systems, we investigate quantum calorimetric detection of individual heat pulses in the sub-meV energy range. We propose a hybrid superconducting injector-calorimeter setup, with the energy of injected pulses carried by tunneling electrons. It is shown that the superconductor constitutes a versatile injector, w
Aims and objectives: The aim of this study was to describe how EL was eased, as narrated by frail older people. Background: Existential loneliness (EL) is an unavoidable part of the human condition. It is a complex phenomenon that has been described as disconnection from life. If EL is acknowledged in the care of older people, the experience of EL can be reduced. Design: In this qualitative study,
This paper introduces a predictive combustion-engine controller for efficient fulfillment of constraints on peak pressure, exhaust temperature and NO emissions. The controller utilizes a in-cylinder pressure sensor, actuation of multiple fuel injections and numerical optimization. A physical model is used to predict pressure changes due to fuel-injection variation. The predicted pressure is used t
Here we show that treatment of the HPV16-positive tonsillar cancer cell line HN26 with DNA alkylating cancer drug melphalan-induced p53 and activated apoptosis. Melphalan reduced the levels of RNA polymerase II and cellular transcription factor Sp1 that were associated with HPV16 DNA. The resulting inhibition of transcription caused a rapid loss of the HPV16 early mRNAs encoding E6 and E7 as a res
Nanowires are presently investigated in the context of various biological and medical applications. In general, these studies are population-based, which results in sub-populations being overlooked. Here, we present a single cell analysis of cell cycle and cell movement parameters of cells seeded on nanowires using digital holographic microscopy for time-lapse imaging. MCF10A normal-like human bre
The aim of this study was to explore parents’ experiences of sleep and rest while admitted to hospital together with their ill child. When a child is hospitalized, it can be a traumatic experience for the entire family. Adaptation to the new situation and new parental responsibilities is necessary. Hospitalized children demand more supervision and care, making sleep disturbance a common challenge
