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From Conflict to Compromise : The importance of mediation in Swedish work stoppages 1907-1927

Institutions for prevention and resolution of labor market conflicts were introduced all over the world in the early twentieth century. In this paper we analyze the impact of mediation on compromise outcomes in Swedish labor market conflicts, using a dataset of geo-coded strikes and lockouts from 1907 to 1927. Causality is identified by using the distance from the mediator's residence to the confl

Identification of the Drosophila and Tribolium receptors for the recently discovered insect RYamide neuropeptides

One year ago, we discovered a new family of insect RYamide neuropeptides, which has the C-terminal consensus sequence FFXXXRYamide, and which is widely occurring in most insects, including the fruitfly Drosophila melanogaster and the red flour beetle Tribolium castaneum (F. Hauser et al., J. Proteome Res. 9 (2010) 5296-5310). Here, we identify a Drosophila G-protein-coupled receptor (GPCR) coded f

Transient erythromycin resistance phenotype associated with peptidyl-tRNA drop-off on early UGG and GGG codons

Expression of minigenes encoding tetra- or pentapeptides MXLX or MXLXV (E peptides), where X is a nonpolar amino acid, renders cells erythromycin resistant whereas expression of minigenes encoding tripeptide MXL does not. By using a 3A' reporter gene system beginning with an E-peptide-encoding sequence, we asked whether the codons UGG and GGG, which are known to promote peptidyl-tRNA drop-off at e

The exosome associates cotranscriptionally with the nascent pre-mRNP through interactions with heterogeneous nuclear ribonucleoproteins

Eukaryotic cells have evolved quality control mechanisms to degrade aberrant mRNA molecules and prevent the synthesis of defective proteins that could be deleterious for the cell. The exosome, a protein complex with ribonuclease activity, is a key player in quality control. An early quality checkpoint takes place cotranscriptionally but little is known about the molecular mechanisms by which the e

Influences on gene expression in vivo by a Shine-Dalgarno sequence

The Shine-Dalgarno (SD+: 5'-AAGGAGG-3') sequence anchors the mRNA by base pairing to the 16S rRNA in the small ribosomal subunit during translation initiation. We have here compared how an SD+ sequence influences gene expression, if located upstream or downstream of an initiation codon. The positive effect of an upstream SD+ is confirmed. A downstream SD+ gives decreased gene expression. This effe

European Banks and the Rise of International Finance: The Post-Bretton Woods Era

European Banks and the Rise of International Finance examines the historical origins of the financialised world we live in by analysing the transformations in world finance which occurred in the decade from the first oil crisis of 1973, until the debt crisis of 1982. This a crucial and formative decade for understanding the modern financial landscape, but it is still mostly unexplored in economic

Commercial and Financial Services

This chapter deals with the performance of commercial and financial services in Europe. Companies in both sectors have undergone considerable concentration in all analysed countries, but those from Great Britain, Germany, and France emerged as the largest companies in Europe from the early twentieth century onwards. Most impressive, however, has been the expansion of the size and business of banks

Benefits and risks with acellular dermal matrix (ADM) and mesh support in immediate breast reconstruction : a systematic review and meta-analysis

In modern implant-based immediate breast reconstruction, it has become common to use biological acellular dermal and synthetic matrices in combination with a tissue expander or an implant. The aim of this systematic review was to examine differences in recurrence of cancer, impact on oncological treatment, health related quality of life, complications and aesthetic outcome between matrix and no ma

The use of sociocultural valuation in sustainable environmental management

The integration of sociocultural valuations (SCV) within an ecosystem services (ES) framework is increasingly being required in environmental management contexts. Yet, this raises important questions: how do we approach SCV when people's perceptions are based on unbalanced information and advocate for detrimental actions? How then should SCV results be used? Should they be used to steer decisions?

Declining oxygen in the global ocean and coastal waters

Oxygen is fundamental to life. Not only is it essential for the survival of individual animals, but it regulates global cycles of major nutrients and carbon. The oxygen content of the open ocean and coastal waters has been declining for at least the past half-century, largely because of human activities that have increased global temperatures and nutrients discharged to coastal waters. These chang

Mechanosensing Using GaInP Nanowires

Mechanical forces exists in many cellular processes, including cell proliferation, migration, rearrangement and differentiation. The transformation of cancer cells from normal cells, cancer metastasis and cell rearrangement during morphogenesis all involve changes in cellular mechanical forces. Although there are some studies about normal cell and cancer cell force measurements, a direct compariso

Omförhandlingar : Kropp, replik, etik

Renegotiations: Body, Line, Ethics departs from questions concerning authorship and agency for actors in institutionalised settings and moves towards a discussion on ethics, responsibility and possibilities in the body – text relationship. The question of how bodies can be renegotiated in and by the theatrical line is central to the work. Against a backdrop of previous and other stage productions

The future of sustainability science: a solutions-oriented research agenda

Over the last decade, sustainability science has been at the leading edge ofwidespread efforts from the social and natural sciences to produce use-inspired research.Yet, how knowledge generated by sustainability science and allied fields will contribute totransitions toward sustainability remains a critical theoretical and empirical question forbasic and applied research. This article explores the

Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain

Degradation of membrane phospholipids (PLs) is a well known phenomenon in acute brain injuries and is thought to underlie the disturbance of vital cellular membrane functions. In the present study glycerol, an end product of PL degradation, was examined in brain interstitial fluid as a marker of PL breakdown following experimental traumatic brain injury (TBI) using microdialysis. TBI was induced i

Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes

Melanoma represents a malignant disease with steadily increasing incidence. UV-irradiation is a recognized key factor in melanoma initiation. Therefore, the efficient prevention of UV tissue damage bears a critical potential for melanoma prevention. In this study, we tested the effect of UV irradiation of normal keratinocytes and their consequent interaction with normal and cancer-associated fibro

Intracerebral microdialysis in neurointensive care : the use of urea as an endogenous reference compound

OBJECT: When evaluating the results of intracerebral microdialysis, the in vivo performance of the microdialysis probe must be considered, because this determines the fraction of the interstitial concentration obtained in the microdialysis samples. The in vivo performance is dependent on several factors, for example, the interstitial compartment's diffusion characteristics, which may vary during t

Active listing and more consultations in primary care are associated with reduced hospitalisation in a Swedish population

Background: Healthcare systems are complex networks where relationships affect outcomes. The importance of primary care increases while health care acknowledges multimorbidity, the impact of combinations of different diseases in one person. Active listing and consultations in primary care could be used as proxies of the relationships between patients and primary care. Our objective was to study ho

Paradoxical increase in neuronal DNA fragmentation after neuroprotective free radical scavenger treatment in experimental traumatic brain injury

The mechanisms and role of nerve cell death after traumatic brain injury (TBI) are not fully understood. The authors investigated the effect of pretreatment with the oxygen free radical spin trap alpha-phenyl-N-tert-butyl-nitrone (PBN) on the number of neurons undergoing apoptosis after TBI in rats. Apoptotic cells were identified by the TUNEL method combined with the nuclear stain, Hoechst 33258,