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Substrate-size choice in European eel (Anguilla anguilla) elvers is not altered by piscivore chemical cues

The European eel Anguilla anguilla Linnaeus 1758 is critically endangered with recruitment estimated at 5–10% of historical levels. Enhancing survival of recruits is pivotal for conservation, and restoration should consider habitat choice of elvers ascending river systems. We experimentally show that newly ascended elvers choose small pebble habitat over finer and larger substrates, regardless of

Domain wall-grain boundary interactions in polycrystalline Pb(Zr0.7Ti0.3)O3 piezoceramics

Interactions between grain boundaries and domain walls were extensively studied in ferroelectric films and bicrystals. This knowledge, however, has not been transferred to polycrystalline ceramics, in which the grain size represents a powerful tool to tailor the electromechanical and dielectric response. Here, we relate changes in dielectric and electromechanical properties of a bulk polycrystalli

Management of Advanced Therapies in Parkinson's Disease Patients in Times of Humanitarian Crisis : The COVID-19 Experience

Background: Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the potential to differentially disadvantage chronically ill patients, including those with Parkinson's disease (PD). The first health care reaction has been to limit access to clinics and neurology wards to preserve fragile pat

From socialist hero to capitalist icon : The cultural transfer of the East German children’s television programme Unser Sandmännchen to Sweden in the early 1970s

Based on a case study of the import of the German Democratic Republic (GDR)children’s programmeUnser Sandm€annchento Sweden in the early 1970s, thisarticle explores the cultural recoding at work in the processes of transnational mediaexchange. Using archival source material from both Germany and Sweden as well asSwedish press debate, the article argues for an entangled media perspective on ColdWar

Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI

Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) approach was developed to simultaneously monitor d-glucose uptake and clearance in both brain parenchyma and cerebrospinal fluid (CSF). We observed substantially higher uptake in parenchyma of young (6 months) transgenic AD mice compared to age-matc

IgG Fc sialylation is regulated during the germinal center reaction upon immunization with different adjuvants

BACKGROUND: Effector functions of IgG antibodies (Abs) are regulated by their Fc N-glycosylation pattern. IgG Fc glycans that lack galactose and terminal sialic acid residues correlate with the severity of inflammatory (auto)immune disorders and have also been linked to the protection against viral infection and discussed in the context of vaccine-induced protection. In contrast, sialylated IgG Ab

Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels

It is not known how ghrelin affects insulin secretion in human islets from patients with type 2 diabetes (T2D) or whether islet ghrelin expression or circulating ghrelin levels are altered in T2D. Here we sought out to identify the effect of ghrelin on insulin secretion in human islets and the impact of T2D on circulating ghrelin levels and on islet ghrelin cells. The effect of ghrelin on insulin

Structure, Action and Change: A Bourdieusian Perspective on the Preconditions for a Degrowth Transition

A deprioritization of economic growth in policy making in the rich countries will need to be part of a global effort to re-embed economy and society into planetary boundaries. However, societal support for a degrowth transition remains for the time being moderate, and it is not well understood as yet why this is the case. This article argues that Pierre Bourdieu’s sociology can help theorize socie

Sharing economy business models for sustainability

Background: The predominant focus of academic research on the sharing economy has been on Airbnb and Uber; to this extent, the diversity of business models ascribed to the sharing economy has not yet been sufficiently explored. Greater conceptual and empirical research is needed to increase understanding of business models in the sharing economy, particularly attributes that deliver on its purport

Ozone dose dependent formation and removal of ozonation products of pharmaceuticals in pilot and full-scale municipal wastewater treatment plants

The removal of micropollutants from municipal wastewater is challenged by the number of compounds with diverse physico-chemical properties. Ozonation is increasingly used to remove micropollutants from wastewater. However, ozonation does not necessarily result in complete mineralization of the organic micropollutants but rather transforms them into new compounds which could be persistent or have a

From lab-scale to on-site pilot trials for the recovery of hemicellulose by ultrafiltration: Experimental and theoretical evaluations

Spent sulfite liquor (SSL) is a byproduct of the sulfite pulping process of wood. SSL usually contains monosugars and lignosulfonates, which are fermented to produce ethanol and dried to generate lignosulfonate salts. However, the SSL that was used in this work was derived from the first step of a 2-step sulfite pulping process of softwood under mild pulping conditions in the first stage of cookin

Basic study on estimation method of wall shear stress in common carotid artery using blood flow imaging

In this paper, we propose a method for adaptive selection of the kernel size used in estimation of the wall shear stress (WSS) based on flow velocity profiles obtained by the blood flow imaging method based on enhancement of RF echo signals from blood cells using a singular value decomposition based clutter filter. Two simulation phantom experiments with the Field II program were performed to vali

Subclonal patterns in follow-up of acute myeloid leukemia combining whole exome sequencing and ultrasensitive IBSAFE digital droplet analysis

We studied mutation kinetics in ten relapsing and four non-relapsing patients with acute myeloid leukemia by whole exome sequencing at diagnosis to identify leukemia-specific mutations and monitored selected mutations at multiple time-points using IBSAFE droplet digital PCR. Five to nine selected mutations could identify and track leukemic clones prior to clinical relapse in 10/10 patients at the

Dynamic Spatio-Temporal Tweet Mining for Event Detection : A Case Study of Hurricane Florence

Extracting information about emerging events in large study areas through spatiotemporal and textual analysis of geotagged tweets provides the possibility of monitoring the current state of a disaster. This study proposes dynamic spatio-temporal tweet mining as a method for dynamic event extraction from geotagged tweets in large study areas. It introduces the use of a modified version of ordering

Spatial and temporal distribution patterns of Precambrian mafic dyke swarms in northern Mauritania (West African craton) : analysis and results from remote-sensing interpretation, geographical information systems (GIS), Google Earth ™ images, and regional geology

We used remote sensing, geographical information systems, Google Earth™ images, and regional geology in order to (i) improve the mapping of linear structures and understand the chronology of different mafic dyke swarms in the Ahmeyim area that belongs to the Archean Tasiast-Tijirit Terrane of the Reguibat Shield, West African craton, NW Mauritania. The spatial and temporal distributions with the t

Serine-deficiency syndromes

Purpose of review: Serine-deficiency disorders comprise a new group of neurometabolic diseases and are caused by defects in the biosynthesis of the amino acid L-serine. In contrast to most neurometabolic disorders, serine-deficiency disorders are potentially treatable. Furthermore, the severe neurological symptoms observed in patients underscore the important roles of the serine biosynthetic pathw

Extracellular traps : An ancient weapon of multiple kingdoms

The discovery, in 2004, of extracellular traps released by neutrophils has extended our understanding of the mode of action of various innate immune cells. This fascinating discovery demonstrated the extracellular trapping and killing of various pathogens by neutrophils. During the last decade, evidence has accumulated showing that extracellular traps play a crucial role in the defence mechanisms

Effect of delay between nuclear medicine scanning and sentinel node biopsy on outcome in patients with cutaneous melanoma

Background: Sentinel lymph node biopsy (SLNB) is an important staging tool for the management of melanoma. A multicentre study was done to validate previous findings that the timing of lymphoscintigraphy influences the accuracy of SLNB and patient outcomes, particularly survival. Methods: Data were reviewed on patients undergoing SLNB for melanoma at three centres in the UK and Sweden, examining t