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Feeding Honeybee Colonies with Honeybee-Specific Lactic Acid Bacteria (Hbs-LAB) Does Not Affect Colony-Level Hbs-LAB Composition or Paenibacillus larvae Spore Levels, Although American Foulbrood Affected Colonies Harbor a More Diverse Hbs-LAB Community

The main current methods for controlling American Foulbrood (AFB) in honeybees, caused by the bacterial pathogen Paenibacillus larvae, are enforced incineration or prophylactic antibiotic treatment, neither of which is fully satisfactory. This has led to an increased interest in the natural relationships between the pathogenic and mutualistic microorganisms of the honeybee microbiome, in particula

IMPACT OF A TERTIARY ELIGIBILITY THRESHOLD ON TERTIARY EDUCATION AND EARNINGS : A DISCONTINUITY APPROACH

This study uses a discontinuity in the Swedish tertiary eligibility requirement to estimate the probability of enrolling in tertiary education, and the payoff thereof. Regression discontinuity results, show that achieving tertiary eligibility in upper-secondary education, increases the probability of enrolling in tertiary education by around 10–15 and 7 percentage points for students who enrolled

Bedside interpretation of simplified continuous EEG after cardiac arrest

Background: Continuous EEG-monitoring (cEEG) in the ICU is recommended to assess prognosis and detect seizures after cardiac arrest but implementation is often limited by the lack of EEG-technicians and experts. The aim of the study was to assess ICU physicians ability to perform preliminary interpretations of a simplified cEEG in the post cardiac arrest setting. Methods: Five ICU physicians recei

Palliative short-course hypofractionated radiotherapy followed by chemotherapy in esophageal adenocarcinoma : the phase II PALAESTRA trial

Background: The majority of patients with incurable esophageal adenocarcinoma suffer from dysphagia. We assessed a novel treatment strategy with initial short-course radiotherapy followed by chemotherapy with the primary aim to achieve long-term relief of dysphagia. Methods: This phase II trial included treatment-naîve patients with dysphagia due to esophageal adenocarcinoma not eligible for curat

Bone and joint complications and reduced mobility are associated with pain in children with cerebral palsy

Aim: To investigate the relationships between pain in the lower extremities and back, and spasticity, bone/joint complications and mobility. Methods: Retrospective population-based registry study. Participants (N = 3256) with cerebral palsy (CP), 2.5-16 years of age, participating in the Swedish Cerebral Palsy Follow-up Program were included. Spasticity was measured using scissoring and the Modifi

Elder law and its subject : The contextualised ageing individual

Elder law is often approached in terms of a 'body' of law. In this article, I argue for a contextualised and externalised perspective on the ageing individual as the subject of elder law. Elder law relates to the implications of law as an institutionalisation of society seen through the lens of older persons. The aged subject is a contested and differentiated social construct to be studied in rela

A Qualitative Study of Caregivers’ Experiences, Motivation and Challenges Using a Web-Based Mindfulness Intervention

Caregivers report experiences of stress and burden that can affect their health negatively. Web-based mindfulness interventions have shown beneficial health effects in clinical and non-clinical populations, including caregivers. The study’s aim was to explore the experiences of a web-based mindfulness program, including motivation and challenges to use, in caregivers of a person with somatic illne

Lipschitz continuity for weighted harmonic functions in the unit disc

We study membership in Lipschitz classes (Formula presented.) for a class of α-harmonic functions in the open unit disc (Formula presented.) in the complex plane. From earlier work by Olofsson and Wittsten we know that such an α-harmonic function u is the α-harmonic Poisson integral (Formula presented.) of its boundary value function f on the unit circle (Formula presented.). We determine when the

The institutionalisation of commercialism in the audit profession : How auditors constitute the commercial self in a large Chinese audit firm

Purpose: Previous literature on the commercialisation of the audit profession has focused on the coercive force of macro-institutional structures. The purpose of this paper is to focus on the agency of individual auditors and examine their active construction of the commercial self in a Big Four audit firm in China. Design/methodology/approach: This paper applied a qualitative research approach to

The δ13C chemostratigraphy of Ordovician global stage stratotypes : geochemical data from the Floian and Sandbian GSSPs in Sweden

The δ13C chemostratigraphy of five of the seven Ordovician global stages has been published previously but no such data have been available from the Floian GSSP and most of the Sandbian GSSP in Sweden. This lack of information has now been remedied by isotope data obtained from series of closely spaced shale samples collected from the Floian stratotype at Diabasbrottet in Västergötland and the San

Contextualizing Policy : Understanding Implementation under Socio-technical Transitions

Over the past 40 years, implementation of public policy has been developed into a mature but heterogenous field of research. Despite much attention paid to the context in which implementation occurs, studies thus far has only to a limited extent been concerned with how major socio-technological transitions affect the conditions for implementing policy. As societies experience major socio-technolog

Cause-Specific Mortality in Gout : Novel Findings of Elevated Risk of Non–Cardiovascular-Related Deaths

Objective: To examine cause-specific mortality beyond cardiovascular diseases (CVDs) in patients with gout compared to the general population. Methods: We included all residents of Skåne (Sweden) age ≥18 years in the year 2002. Using the Skåne Healthcare Register, we identified subjects with a new diagnosis of gout (2003–2013) and matched each person with gout with 10 comparators free of gout, by

Inter Individual Variation and Factors Regulating the Formation of Phosphatidylethanol

Background: Alcohol use disorders are a major but often unrecognized health problem. Alcohol markers can therefore be of great value for diagnosis, follow-up, and treatment evaluation. Phosphatidylethanol in blood (B-PEth) is an alcohol biomarker with higher clinical sensitivity and specificity than commonly used alcohol markers but has shown a considerable interindividual variation in relation to

Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice

Mice homozygous for the human GRACILE syndrome mutation (Bcs1lc.A232G) display decreased respiratory chain complex III activity, liver dysfunction, hypoglycemia, rapid loss of white adipose tissue and early death. To assess the underlying mechanism of the lipodystrophy in homozygous mice (Bcs1lp.S78G), these and wild-type control mice were subjected to a short 4-hour fast. The homozygotes had low

Multiple-stressor effects of dicyandiamide (DCD) and agricultural stressors on trait-based responses of stream benthic algal communities

Agricultural practices often result in multiple stressors affecting stream ecosystems, and interacting stressors complicate environmental assessment and management of impacted streams. The nitrification inhibitor dicyandiamide (DCD) is used for nitrogen management on farmland. Effects of leached DCD on stream ecosystems are still largely unstudied, even though it could be relevant as a stressor on

Exploring trophic niches and parasite communities of sympatric Arctic charr and brown trout populations of southern Norway

Catchment-scale variation between lake habitats has the potential to simultaneously influence the trophic niche and parasite community of fish hosts. In this study, we investigated the trophic niche and parasite community of sympatric Arctic charr and brown trout populations from two inter-connected southern Norwegian lakes at different altitudes. Arctic charr and brown trout occupied profundal an

Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) impacts many veterans and active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms, stigma within military populations, and limitations identifying those at risk. Prior studies suggest that PTSD may be a systemic illness, affecting not just the brain, but the entire body. Therefore, disease signals likely span multipl

Biotic interactions modify multiple-stressor effects on juvenile brown trout in an experimental stream food web

Agricultural land use results in multiple stressors affecting stream ecosystems. Flow reduction due to water abstraction, elevated levels of nutrients and chemical contaminants are common agricultural stressors worldwide. Concurrently, stream ecosystems are also increasingly affected by climate change. Interactions among multiple co-occurring stressors result in biological responses that cannot be

High-throughput amplicon sequencing and stream benthic bacteria : Identifying the best taxonomic level for multiple-stressor research

Disentangling the individual and interactive effects of multiple stressors on microbial communities is a key challenge to our understanding and management of ecosystems. Advances in molecular techniques allow studying microbial communities in situ and with high taxonomic resolution. However, the taxonomic level which provides the best trade-off between our ability to detect multiple-stressor effec

Multiple-stressor effects on stream invertebrates : DNA barcoding reveals contrasting responses of cryptic mayfly species

Most freshwater ecosystems are subject to multiple anthropogenic stressors, which commonly reduce biodiversity across all levels. Existing freshwater bioassessment programmes aim at identifying responses of aquatic biota to stressors. For practical reasons, higher-level taxonomic groups (e.g. genus or family) are often used in these programmes. This approach, however, may bias assessment results a