Thrombosis in myeloproliferative neoplasms (MPNs) is an important clinical problem, and risk-stratified management is essential. To identify the clinical characteristics of thrombosis in patients with MPNs, a nationwide multi-institutional retrospective analysis (JSH-MPN-R18) was conducted. The aim of the present study was to perform a sub-analysis of JSH-MPN-R18 findings to clarify the predictive

This research addresses action research (AR) as a meta-methodology and uses an operations development project as an illustration to provide some insights on AR as a meta-methodology. First, we report on a six-month action research (AR) project concerning analysing and improving production and inventory performance in an industrial firm in the food and beverage industry. The implementation of a new

This paper presents a comparison between a Itl-bit asynchronous SAR (ASAR) ADC and a 10-bit synchronous SAR (SSAR) ADC, both designed and simulated in a 22-nm FDSOI CMOS process. To further support the simulation results, the ASAR ADC has also been fabricated and measurements are pre-sented. As opposed to the abrupt SNDR collapse in the SSAR ADC, the SNDR of the ASAR ADC shows a more graceful deg-

This chapter focuses on industrialization and family behavior during the twentieth century against the backdrop of economic and institutional change. It documents trends regarding marriage and fertility and union dissolution from a gender perspective, and explores the role of socioeconomic status (SES) for these processes. Findings confirm patterns regarding gender and family consistent with that

We studied Rubus wahlbergii and related species in R. sect. Corylifolii, primarily in Sweden, using DNA microsatellites. The results show that the material can be divided into three species: R. wahlbergii s.s. which occurs along the Swedish coast from Bohuslän to Uppland, R. nordicus which occurs on the western coast all the way south to north-western Skåne, and a previously unrecognized taxon whi

The aim of the present European Stroke Organisation (ESO) guideline is to provide evidence-based recommendations on the acute management of patients with basilar artery occlusion (BAO). These guidelines were prepared following the Standard Operational Procedure of the ESO and according to the GRADE methodology. Although BAO accounts for only 1%–2% of all strokes, it has very poor natural outcome.

Background: Early substitution of calcineurin inhibitor (CNI) with mammalian target of rapamycin inhibitors has been shown to improve kidney function and reduce intimal hyperplasia in heart transplant (HTx) recipients but data on long-term outcome of such a regime are still sparse. Methods: In the SCHEDULE trial, 115 de novo HTx recipients were randomized to (1) everolimus with reduced exposure of

Denna sammanläggningsavhandling undersöker strategisk kommunikation av utrikespolitik som en dynamisk process, där en rad olika aktörer är inblandade. Utrikespolitik konceptualiseras som en diskurs som samproduceras av statliga aktörer, praktiker inom offentlig diplomati och publiker i olika kommunikationsmiljöer. I avhandlingen argumenteras för att makten i dessa samproduktionspraktiker flödar i This dissertation examines strategic communication of foreign policy as a dynamic process, in which a variety of actors are involved. To achieve this, foreign policy is conceptualized as a discourse that is co-produced by the government, public diplomacy practitioners, and publics in different communication settings. The thesis argues that in these practices of co-production, power flows in and fr

We study how co-creation practices influence explorative and exploitative learning in five collaborative construction projects with partnering arrangements. Drawing on a longitudinal case study, our findings reveal two different types of explorative learning processes (i.e., adaptation and radical development) and three different exploitative learning processes (i.e., incremental development, know

Objective: Occupational exposure to welding fumes is linked to a higher risk of cardiovascular disease; however, the threshold exposure level is unknown. Here, we aimed to identify changes in proteins associated with cardiovascular disease in relation to exposure to welding fumes. Methods: Data were obtained from two timepoints six years apart for 338 non-smoking men (171 welders, 167 controls); o

The need for radical transformations to respond to the environmental polycrises of climate change, biodiversity loss, and pollution has come to the forefront of political and academic debates. Nation states must have transformative capacity, meaning the ability to ignite, enable, and steer large-scale sustainability transformations. However, despite its importance, there remains a significant gap

Background: The aim was to compare survival for incidental gallbladder cancer (IGBC), respectively, preoperatively suspected gallbladder cancer (GBC), subjected to surgery for different pathological tumour (pT) stages and in different treatment groups in a national cohort. Methods: Data were collected and crosslinked from two national quality registers, SweLiv (2009–2019) and GallRiks (2009–2016).

The rise of augmented reality (AR) technology offers potential opportunities for the tourism industry and academia. Drawing upon narrative transportation and presence theory, this paper investigates the relationship between vividness, narrative transportation, sense of presence, and visiting other AR destination. The empirical findings indicate that vividness enhances narrative transportation and

Changes in biomarker levels of Alzheimer’s disease (AD) reflect underlying pathophysiological changes in the brain and can provide evidence of direct and downstream treatment effects linked to disease modification. Recent results from clinical trials of anti–amyloid β (Aβ) treatments have raised the question of how to best characterize the relationship between AD biomarkers and clinical endpoints.

Inte sällan beskrivs byggbranschen som konservativ och motvillig till förändringar, både av folk i branschen, av forskare samt av folk i allmänhet. Likväl har byggbranschen under årens lopp genomgått ett antal förändringar, ofta som reaktioner på nya förutsättningar skapade av förändringar i det omgivande samhället. Den här artikeln redovisar hur ett antal projektledare i stora byggprojekt uppfatt

We document the socioeconomics of wind power expansion in Sweden using two metrics. First, we compute the difference in socioeconomic status (SES) between residents exposed to wind power (0-2 km from the closest turbine) and those not exposed. For each site, the metric is computed ten years prior until five years after construction. When the comparison group is other residents within the same muniWe document the socioeconomics of wind power expansion in Sweden using two metrics. First, we compute the difference in socioeconomic status (SES) between residents exposed to wind power (0-2 km from the closest turbine) and those not exposed. For each site, the metric is computed ten years prior until five years after construction. When the comparison group is other residents within the same muni

Flera stora byggprojekt pågår och planeras i Sverige, varav flera är skattefinansierade. Det ligger därför i både samhällets och byggbranschens parters intresse att utveckla kunskapen kring hur stora byggprojekt organiseras och leds, aktat de många samhällsförändringar som Sverige genomgått de senaste decennierna. Denna studie har följaktligen studerat hur olika samhällsförändringar påverkat förut

We show that a profinite group, in which the centralisers of non-trivial elements are metabelian, is either virtually pro-p or virtually soluble of derived length at most 4. We furthermore show that a prosoluble group, in which the centralisers of non-trivial elements are soluble of bounded derived length, is either soluble or virtually pro-p.