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A fast output-sensitive algorithm for Boolean matrix multiplication

We use randomness to exploit the potential sparsity of the Boolean matrix product in order to speed up the computation of the product. Our new fast output-sensitive algorithm for Boolean matrix product and its witnesses is randomized and provides the Boolean product and its witnesses almost certainly. Its worst-case time performance is expressed in terms of the input size and the number of non-zer

Patterns of inbreeding depression in a population of Brassica cretica (Brassicaceae): evidence from family-level analyses

In this investigation, we have collected family-structured data from a partly self-compatible, outcrossing population of Brassica cretica to estimate and compare the effects of one-generation selfing on different types of characters. Inbreeding not only depressed characters that should be positively correlated with fitness irrespective of habitat, e.g. germinability, leaf number and inflorescence

Scaling properties of azimuthal anisotropy in Au plus Au and Cu plus Cu collisions at root s(NN)=200 GeV

Differential measurements of elliptic flow (v(2)) for Au+Au and Cu+Cu collisions at root s(NN)=200 GeV are used to test and validate predictions from perfect fluid hydrodynamics for scaling of v(2) with eccentricity, system size, and transverse kinetic energy (KET). For KET equivalent to m(T)-m up to similar to 1 GeV the scaling is compatible with hydrodynamic expansion of a thermalized fluid. For

A study on turbulent flow characteristics in ducts of relevance for heat exchangers

The performance of an explicit algebraic stress model with a cubic equation for closure constants is assessed in predicting the turbulent flow dynamics of ducts relevant for heat exchangers. The use of a cubic equation allows elimination of any damping functions in the tensor representation for the Reynolds stresses and thereby improves prediction of turbulent stresses theoretically. The methodolo

Scotopic colour vision in nocturnal hawkmoths

Humans are colour-blind at night, and it has been assumed that this is true of all animals. But colour vision is as useful for discriminating objects1 at night as it is during the day. Here we show, through behavioural experiments, that the nocturnal hawkmoth Deilephila elpenor uses colour vision to discriminate coloured stimuli at intensities corresponding to dim starlight (0.0001 cd m-2). It can

Critical role of P-selectin-dependent leukocyte recruitment in endotoxin-induced intestinal barrier dysfunction in mice.

Objective: To define the importance of leukocyte recruitment in endotoxin-induced gut permeability. Materials and methods: 31 male C57BL/6 mice were challenged with lipopolysaccharide (LPS). Ileal permeability was measured in Ussing chambers and leukocyte-endothelium interactions studied with intravital fluorescence microscopy after 18 h. Results: LPS caused a clear-cut increase in leukocyte accum

Polymeric Cryogels as Promising Materials of Biotechnological Interest.

Cryogels are gel matrices that are formed in moderately frozen solutions of monomeric or polymeric precursors. Cryogels typically have interconnected macropores (or supermacropores), allowing unhindered diffusion of solutes of practically any size, as well as mass transport of nano- and even microparticles. The unique structure of cryogels, in combination with their osmotic, chemical and mechanica

Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins.

The C-terminal G3 domains of lecticans mediate crosslinking to diverse extracellular matrix (ECM) proteins during ECM assembly, through their C-type lectin (CLD) subdomains. The structure of the rat aggrecan CLD in a Ca(2+)-dependent complex with fibronectin type III repeats 3-5 of rat tenascin-R provides detailed support for such crosslinking. The CLD loops bind Ca2+ like other CLDs, but no carbo

HLA-DQB1 genotypes, islet antibodies and beta cell function in the classification of recent-onset diabetes among young adults in the nationwide Diabetes Incidence Study in Sweden.

The World Health Organization considers an aetiological classification of diabetes to be essential. The aim of this study was to evaluate whether HLA-DQB1 genotypes facilitate the classification of diabetes as compared with assessment of islet antibodies by investigating young adult diabetic patients. Blood samples were available at diagnosis for 1,872 (90%) of the 2,077 young adult patients (aged

myo-Inositol monophosphatase is an activated target of calbindin D28k.

Calbindin D28k (calbindin) is a member of the calmodulin superfamily of Ca2+ -binding proteins. An intracellular target of calbindin was discovered using bacteriophage display. Human recombinant calbindin was immobilized on magnetic beads and used in affinity purification of phage-displayed peptides from a random 12-mer peptide library. One sequence, SYSSIAKYPSHS, was strongly selected both in the

Density functional theory for polymer fluids with molecular weight polydispersity

We develop a density-functional theory for polydisperse polymer fluids satisfying the Schulz-Flory distribution. The resulting equations are remarkably simple and quickly solved, the computational effort scaling with the polydispersity index, rather than the average molecular weight. Equilibrium, or "living", polymers enter naturally as very polydisperse samples. We illustrate the importance of po

Eye model with controllable lens scattering

A model of human eye for experiments in vision research has been developed using PLZT ceramics. This ``artificial eye{''} allows to simulate light scattering caused by cataract in the eye lens. Light scattering of a composite eye lens of the model depends on the electric field applied to a transparent electrooptic PLZT ceramics plate that is attached directly to the lens. The image degradation in

Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells

Murine monoclonal antibodies (mAbs) which specifically react, in immunoblot and immunolocalization experiments, with the human desmosomal cadherins, desmocollins Dsc1 (mAb Dsc1-U100) and Dsc3 (mAb Dsc3-U114), have allowed to study systematically the synthesis of these proteins in tissues and cultured cells. Application of these mAbs in immunofluorescence microscopy on human skin has shown the pres

Partitioning of genetic variation in the weedy clonal herb Aegopodium podagraria (Apiaceae) in Sweden

Although sexual reproduction appears to be rare in many clonal plant species, the majority of clonal species show similar levels of genetic variation to non-clonal plant species. Aegopodium podagraria is a noxious garden weed and has become a successful invader in many natural habitats. Earlier studies have demonstrated population differentiation in life-history traits between different A. podagra

Functional in vitro characterisation of the androgen receptor GGN polymorphism.

Superior androgen receptor (AR) function in subjects carrying a GGN repeat length of 23 (GGN23) has been indicated in vivo. Therefore, the activity of the AR carrying GGN23 combined with CAG22 was compared to the AR with GGN10, 24 and 27, respectively, in the presence of 0.1-100 nM testosterone or DHT. At 100 nM DHT, GGN24 showed 35% lower transactivating activity (95% [CI]: 20-50%) than GGN23. GG

Conjugated linoleic acid increased C-reactive protein in human subjects

We previously showed that conjugated linoleic acid (CLA) increases 15-keto-dihydro-prostaglandin F-2 alpha, a marker for cyclooxygenase-mediated lipid peroxidation and thus an indicator of cyclooxygenase-mediated inflammation. The aim of the present study was to investigate the effects of CLA on other indicators of inflammation in human subjects, including C-reactive protein, TNF-alpha, TNF-alpha

Diversity and phylogeny of mitochondrial cytochrome b lineages from six morphological species of avian Haemoproteus

Species of Haemoproteus (Haemosporida: Haemoproteidae), avian haemosporidians, have traditionally been described based on morphology of their gametocytes and on limited experimental information on their vertebrate host specificity. We investigated to what extent the morphological species are represented by monophyletic groups based on DNA sequence data using 2 different fragment lengths of the cyt