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Laura Saetveit Miles. The Virgin Mary’s Book at the Annunciation : Reading, Interpretation and Devotion in Medieval England. Cambridge: D.S. Brewer, 2020. Pp. 313. $99.00 (cloth).
Reassessing brand co-creation: towards a critical performativity approach
The tenets of indirect inference in Bayesian models
This paper extends the application of Bayesian inference to probability distributions defined in terms of its quantile function. We describe the method of *indirect likelihood* to be used in the Bayesian models with sampling distributions which lack an explicit cumulative distribution function. We provide examples and demonstrate the equivalence of the "quantile-based" (indirect) likelihood to the
Beam manipulation using characteristic mode analysis for switchable beam patch antenna
The operating mechanisms of a planar patch antenna with a parasitic strip is analyzed in this paper. The patch antenna uses a thin parasitic strip to realize beam deflection, which facilitates switchable beam. The beam deflection effect of the parasitic strip can be explained by using characteristic mode analysis (CMA). Specifically, the parasitic strip introduces a new mode that interacts with a
The immune landscape of colorectal cancer
While the clinical importance of CD8+ and CD3+ cells in colorectal cancer (CRC) is well established, the impact of other immune cell subsets is less well described. We sought to provide a detailed overview of the immune landscape of CRC in the largest study to date in terms of patient numbers and in situ analyzed immune cell types. Tissue microarrays from 536 patients were stained using multiplexe
Brain-derived neurotrophic factor, neutrophils and cysteinyl leukotriene receptor 1 as potential prognostic biomarkers for patients with colon cancer
The tumor microenvironment has been recognized as a complex network in which immune cells play an important role in cancer progression. We found significantly higher CD66b neutrophil expression in tumor tissue than in matched normal mucosa in the Malmö colon cancer (CC) cohort and poorer survival of stage I-III patients with high CD66b expression. Additionally, mice lacking CysLT1 R expression (cy
Investigation of hydrogen content and dilution effect on syngas/air premixed turbulent flame using OH planar laser-induced fluorescence
Syngas produced by gasification, which contains a high hydrogen content, has significant potential. The variation in the hydrogen content and dilution combustion are effective means to improve the steady combustion of syngas and reduce NOx emissions. OH planar laser-induced fluorescence technology (OH-PLIF) was applied in the present investigation of the turbulence of a premixed flame of syngas wi
Range of hip abduction after preventive and reconstructive surgery in cerebral palsy : a longitudinal registry study of 307 children
Background and purpose — Hip dislocation in cerebral palsy (CP) is caused by altered muscle forces on the joint during typical hip positioning in adduction–flexion–inward rotation. Preventive surgery includes adductor–psoas lengthening (APL) or varus derotation osteotomy (VDRO) of the proximal femur. We assessed the changes in the hip abduction range after these operations. Patients and methods —
Estimation of the effective doses from typical fluoroscopic examinations with barium contrast
The current study aimed to estimate the effective doses and conversion coefficients (CCs) for typical barium swallow (BS), barium meal (BM) and barium enema (BE) protocols and to evaluate the impact of different examination parameters on the resulting CCs. Data were collected in surgical and therapy departments in St. Petersburg Urban Mariinsky Hospital. Computational models were developed using P
20 years after To Err Is Human : A bibliometric analysis of ‘the IOM report's’ impact on research on patient safety
Modern safety science owes much of its current theories and practical approaches to the critical analysis of socio-technological disasters in the nuclear, chemical, maritime, and aviation industries at the end of the 1970 s and in the 1980 s. The medical field by contrast, was not challenged by a single high profile event, but by the release of a single report by the Institute of Medicine in 1999:
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
The hepatokine follistatin is elevated in patients with type 2 diabetes (T2D) and promotes hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with incident T2D and mechanisms involved. Adjusted hazard ratio (HR) per standard deviation (SD) increase in follistatin levels for T2D is 1.24 (CI: 1.04-1.47, p < 0.05) during 19-year follow-up (n = 4060, Sweden); and 1.31
The Entrepreneurial Story and its Implications for Research
Research is not merely report-writing; it also involves elements of storytelling. In this essay, we reflect on two narrative archetypes in entrepreneurship research: the stories of entrepre- neurship as a road to salvation and means to emancipation. We outline a framework to analyze research from a storytelling perspective, apply this framework to identify implicit assumptions and methodological b
Association of comprehensive mental health with incident cardiovascular disease : A prospective cohort study
BACKGROUND: Evidence is limited regarding the impact of comprehensive mental health on the risk of subsequent cardiovascular events.OBJECTIVES: To investigate the association of mental health status with cardiovascular disease (CVD) in the UK Biobank.METHODS: This prospective study included 339,616 participants aged 40 to 69 years who were enrolled between 2006 and 2010 and were followed up to 202
Impact of the Covid-19 pandemic on primary care utilization : evidence from Sweden using national register data
OBJECTIVE: To analyze changes in primary care utilization as a result of the Covid-19 pandemic. Swedish national register data from 2019 to 2020 on utilization of services were used to compare overall utilization levels and across types of contacts and patient groups. A specific objective was to assess the extent to which remote types of patient consultations were able to compensate for any observ
Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish Population
Hereditary mechanisms are partially responsible for individual differences in sensitivity to and the preference for sweet taste. The primary aim of this study was to examine the associations between 10 genetic variants and the intake of total sugar, added sugar, and sugars with sweet taste (i.e., monosaccharides and sucrose) in a middle-aged Swedish population. Two single nucleotide polymorphisms
Comparison of organ absorbed doses in whole-body computed tomography scans of paediatric and adult patient models estimated by different methods
This study aimed to identify the uncertainty in estimations of organ absorbed dose using dedicated software by comparing with corresponding doses measured in physical phantoms. The comparison was performed for whole-body computed tomography (CT) obtained as part of positron emission tomography. Whole-body CT scans provide an advantage in terms of comparison because all organs are in the primary be
X-Ray and molecular imaging during pregnancy and breastfeeding - When should we be worried?
Some of the ethically most sensitive issues in radiation protection arise at imaging of pregnant - and potentially pregnant - patients and of newborn. This article reviews the current literature and recommendations on imaging during pregnancy and breastfeeding. Risks related to alternative non-ionizing radiation methods are also considered. With few exceptions, exposure of the fetus through radiog
Systemperspektiv på svensk produktion av biojetbränslen : Sammanfattning av ett forskningsprojekt vid Lunds tekniska högskola
Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks
Recent progress in the field of human induced pluripotent stem cells (iPSCs) has led to the efficient production of human neuronal cell models for in vitro study. This has the potential to enable the understanding of live human cellular and network function which is otherwise not possible. However, a major challenge is the generation of reproducible neural networks together with the ability to int