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Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis : results of modified Delphi procedure

Objectives: To evaluate whether the Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis need to be better defined and, if deemed necessary, to reach consensus on the updated definitions. Methods: A modified Delphi procedure was performed among European gynecologists with expertise in ultrasound diagnosis of adenomyosis. To identify MUSA features that might need revision, 15

Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements

Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5+ B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cells as a part of the public IG repertoire. In this study, we collected details on the representation an

Cardiovascular risk factors in attention-deficit/hyperactivity disorder : A family design study of Swedish conscripts

Objective: (1) investigate the associations of attention-deficit/hyperactivity disorder (ADHD) with systolic and diastolic blood pressure, resting heart rate, pulse pressure (PP), physical fitness, and BMI; (2) explore whether cardiovascular risk factors and ADHD share genetic and environmental influences; (3) assess if pharmacological treatment for ADHD influences these associations. Methods: We

Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing

Therapeutic antibodies are transforming the treatment of cancer and autoimmune diseases. Today, a key challenge is finding antibodies against new targets. Phenotypic discovery promises to achieve this by enabling discovery of antibodies with therapeutic potential without specifying the molecular target a priori. Yet, deconvoluting the targets of phenotypically discovered antibodies remains a bottl

Meaning-making in a context of climate change : Supporting agency and political engagement

Responding effectively to climate change requires an understanding of what shapes people’s individual and collective sense of agency and responsibility towards the future. It also requires transforming this understanding into political engagement to support systems change. Based on a national representative survey in Sweden (N = 1,237), this research uses the novel SenseMaker methodology to look i

FashioNordic : Folkcostume as Performance of Genealogy and Place

This article elaborates on the embodiment of heritage via dressing practices in several rural and urban Nordic communities in the United States. Getting dressed is a shared human practice that we engage in and repeat most days, and for special occasions, traditional dress, or folk costume, comes into particular focus. I approach dressing in folk costume as a "situated embodied practice," a mode of

Urban Navigation with LTE using a Large Antenna Array and Machine Learning

Channel fingerprinting entails associating a point in space with measured properties of a received wireless signal. If the propagation environment for that point in space remains reasonably static with time, then a receiver with no knowledge of its own position experiencing a similar channel in the future might reasonably infer proximity to the original surveyed point. In this article, measurement

Search for Dark Matter in events with missing transverse momentum and a Higgs boson decaying into bottom quarks with the ATLAS detector

Many astrophysical observations indicate the existence Dark Matter, which is not predicted by the Standard Model (SM) of particle physics. Many theories beyond the Standard Model (BSM) predict new heavy particles called WIMPs (Weakly Interacting Massive Particles). One way to search for WIMP dark matter is through its pair-production in collider experiments. A possible signature, in this case, is