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For or against 'the business of benchmarking'?

This short response does two things. First, it argues that urban benchmarks have specific and structural limits not identified in the principal essay in this intervention, which curtail the kinds of constructive and critical work such benchmarks might be expected to perform. ISO 37120 is discussed as an example. Second, it proposes a pluralistic approach to engagement and offers six suggestions fo

Nanolithographic Fabrication Technologies for Network-Based Biocomputation Devices

Network-based biocomputation (NBC) relies on accurate guiding of biological agents through nanofabricated channels produced by lithographic patterning techniques. Here, we report on the large-scale, wafer-level fabrication of optimized microfluidic channel networks (NBC networks) using electron-beam lithography as the central method. To confirm the functionality of these NBC networks, we solve an

Mo3Ni2N Nanoparticle Generation by Spark Discharge

Spark ablation is an advantageous method for the generation of metallic nanoparticles with defined particle sizes and compositions. The reaction of the metal particles with the carrier gas during the synthesis and, therefore, the incorporation of those light elements into structural voids or even compound formation was confirmed for hydrides and oxides but has only been suspected to occur for nitr

Environmental expertise for social transformation: roles and responsibilities for social science

What role should social science play in the work for transforming society towards sustainability? The background for this question is that despite massive investments in environmental research and the accumulation of data on the human impact on the environment, action remains insufficient. The severity of the current situation has led to the conclusion that moderate change is not enough; there is

Heart rate characteristic based modelling of atrial fibrillatory rate using implanted cardiac monitor data

OBJECTIVE: The objective of the present study is to investigate the feasibility of using heart rate characteristics to estimate atrial fibrillatory rate (AFR) in a cohort of atrial fibrillation (AF) patients continuously monitored with an implantable cardiac monitor (ICM). We will use a mixed model approach to investigate population effect and patient specific effects of heart rate characteristics

Follow-up and screening for type-2 diabetes mellitus in women with previous gestational diabetes in primary care

ObjectiveGestational diabetes mellitus (GDM) is an established risk factor for developing type 2 diabetes mellitus (T2DM) that is possible to prevent by systematic follow-up and preventive measures. The aim of this study was to examine whether women with previous GDM were offered follow-up in primary care, according to Swedish national guidelines.DesignRetrospective review of electronic medical re

Chemoreception of a Two-Dimensional Cell with Multilayer Diffusion

Previously, Berg and Purcell found an expression for the diffusion current of particles into a set of receptors in their paper Physics of Chemoreception. These receptors were assumed to be uniformly distributed on a spherical cell's surface and the receptors where idealized as circular patches. For their model, the particles' diffusion constant was the same for all points outside of the ce

Sex hormone-dependent and-independent regulation of serum BAFF and TNF in cohorts of transgender and cisgender men and women

Background: The risk of inflammatory diseases is sex-dependent, but it remains unknown whether this is due to the impact of sex hormones or sex chromosomes. Transgender individuals represent a unique cohort for studying the relative influence of endocrine and chromosomal factors. Here we compared serum levels of B-cell activating-factor (BAFF) and tumor necrosis factor (TNF) in transgender men (TM

Building a precision medicine infrastructure at a national level: The Swedish experience

Precision medicine has the potential to transform healthcare by moving from one-size-fits-all to personalised treatment and care. This transition has been greatly facilitated through new high-throughput sequencing technologies that can provide the unique molecular profile of each individual patient, along with the rapid development of targeted therapies directed to the Achilles heels of each disea

Improved survival after laparoscopic compared to open gastrectomy for advanced gastric cancer : a Swedish population-based cohort study

Background: Laparoscopic gastrectomy is increasingly used for the treatment of locally advanced gastric cancer but concerns remain whether similar results can be obtained compared to open gastrectomy, especially in Western populations. This study compared the short-term postoperative, oncological and survival outcomes following laparoscopic versus open gastrectomy based on data from the Swedish Na

Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study

Background: Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive. Methods: We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the EPIC coh

Ordagrann återgivning eller klickbete? : Om citatteckenanvändning i tidningsrubriker

Most newspaper readers in Sweden today obtain news from websites rather than printed newspapers. As a consequence of this, headlines on newspaper websites are often read without the reader considering the article they correspond to. Do these headlines faithfully reproduce quotes found in the corresponding article, or are they better thought of as clickbaits, containing sensational quotes that do n

Dysfagipatienters och vårdpersonals följsamhet till logopediska sväljråd efter FUS

Bakgrund. Dysfagi är en vanlig komplikation efter stroke och andra neurologiska sjukdomar. För att minska konsekvenserna av dysfagi får patienter sväljråd av logoped. När sväljråd inte följs kan det leda till negativa konsekvenser för patienten. Syfte. Den föreliggande uppsatsen önskade undersöka följsamheten på en neurologi- och strokeavdelning. Frågeställningar. Följer patienter med sväljningsIntroduction. Dysphagia is a common complication after stroke and other neurological disorders. To lessen the consequences of dysphagia, patients are given compensatory swallowing strategies and bolus consistency modification from a speech language pathologist. If swallowing recommendations are not followed, it can have negative consequences for the patient. Purpose. The present study aimed to ex