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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

The generation of mice lacking specific components of the transforming growth factor-beta (TGF-beta) signal tranduction pathway shows that TGF-beta is a key player in the development and physiology of the cardiovascular system. Both pro- and anti-angiogenic properties have been ascribed to TGF-beta, for which the molecular mechanisms are unclear. Here we report that TGF-beta can activate two disti

Electrochromic devices operating with electrolytes based on boronate ester compounds and various alkali metal salts

Various polymer electrolytes based on boronate esters and different lithium and sodium salts have been evaluated in electrochromic (EC) devices based on WO3 films. The results showed that the ionic conductivity of the electrolytes was not the most important parameter for the colouration performance of these devices. The use of solid electrolytes containing LiClO4 resulted in a higher colouration p

Signal transduction and calcium sensitivity of smooth muscle contraction

Popular Abstract in Swedish Glatt muskulatur ingår i flera fysiologiskt viktiga organsystem och är involverade i flera sjukdomsprocesser. Glatt muskelkontraktion regleras av variationer i intracellulärt calcium; höjda nivåer aktiverar kinaset MLCK som fosforylerar myosin och initierar kontraktion. Myosin fosfatas (MLCP) avfosforylerar myosin vilket leder till relaxation. Flera intracellulära signaSmooth muscles are components of several physiologically important organs and often involved in disease. Smooth muscle contraction is regulated by variations in intracellular [Ca2+]; increased levels activate the myosin light chain kinase (MLCK) which phosphorylates myosin and initiates contraction. Myosin phosphatase (MLCP) dephosphorylates myosin and promotes relaxation. Several cellular signali

Nanomagnetic and Micromagnetic Properties of Rocks Minerals and Sulphide Oxidation Products

Magnetic and related properties of rocks and products from oxidation of sulphide minerals have been investigated with magnetisation measurements (rocks and oxidation products), magnetic force microscopy (rocks), scanning electron microscopy (rocks and oxidation products), transmission electron microscopy (oxidation products), Mössbauer spectroscopy (oxidation products) and powder X-ray diffraction

Identification of the sex pheromone of the currant shoot borer, Lampronia capitella

Under an artificial light: dark cycle, females of Lampronia capitella were observed calling, with extended terminal abdominal segments, during the first 2 hr of the photoperiod. Extracts of terminal abdominal segments from females elicited large electroantennographic responses from male antennae. Gas chromatography with electroantennographic detection revealed three active peaks. Based on comparis

Evolution of reproductive strategies in the sexually deceptive orchid Ophrys sphegodes: How does flower-specific variation of odor signals influence reproductive success?

The orchid Ophrys sphegodes Miller is pollinated by sexually excited males of the solitary bee Andrena nigroaenea, which are lured to the flowers by visual cues and volatile semiochemicals. In O. sphegodes, visits by pollinators are rare. Because of this low frequency of pollination, one would expect the evolution of strategies that increase the chance that males will visit more than one flower on

On Degradation and Monitoring Tools for Gas and Steam Turbines

Popular Abstract in Swedish Elmarknadens avreglering har medfört att behovet av "condition monitoring" eller tillståndskontroll har ökat. Den nya "marknaden" har medfört en annan typ av aktörer, som till skillnad mot de traditionella kraftbolagen, inte har samma kultur beträffande teknikorganisation. Därför har behovet av övervakningssystem ökat markant. Avhandlingen behandlar dessa ur ett teknisThe revenue from a power plant is strongly dependent on the life cycle cost. Today, when the market conditions for power-producing companies have shifted from a protected market to a deregulated market, the need for tools to monitor power plants has increased significantly. In this new competitive market, targeted revenues and operational economy drive the need for advanced monitoring tools. In th

Treatment with anti-factor VIIa in acute pancreatitis in rats: Blocking both coagulation and inflammation?

Objective. Acute pancreatitis starts as an autodigestive process restricted to the pancreas and progresses to a systemic inflammation via cytokine release into the blood stream. Several inhibitors of the coagulation cascade, including active- siteinactivated factor VIIa, have shown anti- inflammatory properties in other inflammatory models than acute pancreatitis. Free radical scavengers have prov

Intramolecular vibronic dynamics in molecular solids: C60

Vibronic coupling in solid C60 has been investigated with a combination of resonant photoemission spectroscopy (RPES) and resonant inelastic x-ray scattering (RIXS). Excitation as a function of energy within the lowest unoccupied molecular orbital resonance yielded strong oscillations in intensity and dispersion in RPES, and a strong inelastic component in RIXS. Reconciling these two observations

Being victims or beneficiaries? Perspectives on female genital cutting and reinfibulation in Sudan

Abstract in French La mutilation génitale féminine (MGF) ou bien le terme neutre de plus de valeur, l'excision génitale féminine (EGF) est pratiquée un peu partout au Soudan, où environ 90% des femmes subissent le type le plus coûteux de l'infibulation, l'EGF. Une nouvelle approche pour combattre l'EGF au Soudan consiste à reconnaître l'ancienne forme cachée de l'EGF, la reinfibulation après l'accFemale Genital Mutilation (FGM) or the more value neutral term, Female Genital Cutting (FGC) is widely practised in northern Sudan, where around 90% of women undergo the most extensive form of FGC, infibulation. One new approach to combating FGC in Sudan is to acknowledge the previously hidden form of FGC, reinfibulation (RI) after delivery, when the woman is sewn back so much as to mimic virginit

Periodic traveling water waves with isobaric streamlines

It is shown that in water of finite depth, there are no periodic traveling waves with the property that the pressure in the underlying fluid flow is constant along streamlines. In the case of infinite depth, there is only one such solution, which is due to Gerstner.

Laser Diagnostic Techniques with Ultra-High Repetition Rate for Studies in Combustion Environments

When conducting laser based diagnostics in combustion environments it is often desirable to obtain temporally resolved information. This can be due to several factors such as combustion taking place in a turbulent flow field, flame propagation from a spark plug in an initially quiescent combustible mixture, or rapid, multi-point fuel consumption in a homogeneous charge as a result of compression i

Environmental Implications of Product Servicising. - The Case of Outsourced Computing Utilities

Popular Abstract in Swedish Hela livscykeln för en elektronikvara är förknippad med miljöpåverkan. I jämförelse med många andra varor är tillverkningen av elektronik och i synnerhet halvledarkomponenter mycket resurskrävande. Elektroniken ger också upphov till ett antal mycket giftiga utsläpp och avfallsströmmar, såväl från själva tillverkningen som från de uttjänta varorna. Elektronikindustrin haThe life cycle of electronic products is associated with significant environmental impacts. Compared to many other products, the production of electronics and in particular semiconductors is resource intensive and generates a number of highly toxic waste streams in manufacturing and post-consumer stages of product life cycle. Electronics manufacturing industry has been successful in reducing envir