Regional blood flow in rat liver and in inoculated liver tumors was studied before, during and after local hyperthermia treatment at 42.0°C for one hour. Hyperthermia was induced by microwave irradiation of the central liver lobe. The method used for blood flow studies was the clearance of Xenon-133 following portal and intraparenchymal injection. The wash-out curves were analyzed by using a bi-ex

The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive eff

At its heart, this is a case about the reputation of an international symbol of achievement and about managing an iconic brand. The case provides insights into the nature of a prestigious “heritage brand” and its challenges and opportunities to remain relevant and differentiated in the 21st century. In “protecting and safeguarding the standing of the Nobel Prize” the executive board faced the para

Both current and historical settlement forms experience evolutionary, permanent changes to their spatial and socio-economic attributes, not seldom accompanied by dynamic functional transformations. The linkage between functionalism and dynamism, in turn, is one of those elements of conventional geographical theory used to explain the phenomena of urbanization and urbification. While urbanization r

The sharing of indoor space can improve space and energy efficiency. The drivers and barriers to space-sharing initiatives are investigated from the perspectives of building users and building sector practitioners, based on interviews and a workshop. The role of energy performance metrics in promoting space efficiency is further analysed through a literature review. From the users’ perspective, sp

Policy changes in the wake of Covid-19

Health economic evaluations provide decision makers with information whether the health effects of one intervention come at a reasonable cost in relation to a comparator. The existing evidence indicate that health promotion for community-dwelling older people result in a range of positive health outcomes, but there is a general lack of health economic evaluation. The aim was to evaluate cost-effec

Rationale: Symptom relief is a key treatment goal in patients with chronic obstructive pulmonary disease (COPD). However, there are limited data available on the response to bronchodilator therapy in patients at low risk of exacerbations with different levels of symptom severity. This study compared treatment responses in patients with a range of symptom severities as indicated by baseline COPD as

Background: The quality of life (QoL) of patients with osteosarcoma (OS) may be adversely affected by the disease or its treatment. Therefore, it is important to understand the QoL of patients undergoing treatment for OS to improve the QoL. We report on the first prospective international QoL study that was embedded within a large randomized clinical trial from 4 national study groups. Objective:

In order to achieve nominal performance in terms of the dynamic aperture and lifetime of a storage ring, it is important to be able to characterise and correct its second order optics. At the MAX IV 3 GeV storage ring in Lund, Sweden, the linearity of the 2nd order dispersion with chromatic sextupole field strengths has been utilised to investigate the sextupole circuits. The beating induced in th

We conducted a multicentre test-negative case–control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination