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Evolutionary history of the extinct Sardinian dhole

The Sardinian dhole (Cynotherium sardous) was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene. Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African hunting doThe Sardinian dhole (Cynotherium sardous)1 was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene.2-5 Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African huntin

A PIN-ON-DISC STUDY ON THE FRICTION, WEAR AND AIRBORNE PARTICLE EMISSION FROM RECYCLED BRAKE PAD MATERIAL

A brake pad is usually replaced before it is totally worn off. Some of these pads are re-melted as scarps in electrical arc furnace process, arising some concerns for the potential emissions due to the combustion of the organic component of the friction material and pad underlayer. To a lower extent, the other exhaust pads are taken to the scrap yard as waste. The concept of this study is to recyc

Vapor-solid-solid growth dynamics in GaAs nanowires

Semiconductor nanowires are promising material systems for coming-of-age nanotechnology. The usage of the vapor-solid-solid (VSS) route, where the catalyst used for promoting axial growth of nanowires is a solid, offers certain advantages compared to the common vapor-liquid-solid (VLS) route (using a liquid catalyst). The VSS growth of group-IV elemental nanowires has been investigated by other gr

Barriers to fossil-free urban goods transport systems : An explorative study of a Nordic city

Purpose The purpose is to identify, categorise and describe barriers for a fossil-free transport system for urban goods. Design/methodology/approach The barriers are studied from a systems perspective in a case of a mid-sized Nordic city. Data are collected from 15 semi-structured interviews with officials from the city and representatives of private companies, and from policy documents and a work

Is climate or direct human influence responsible for discharge decrease in the tunisian merguellil basin?

Climate change and direct anthropogenic impact are recognized as two major factors affecting catchment runoff. This study investigated the separate effect of each of these factors for runoff from the important Tunisian Merguellil catchment. For this purpose, more than forty years of hydrological data were used. The methodology was based on hydrological characterization, NDVI index to monitor land

Unfolding the Medial Temporal Lobe Cortex to Characterize Neurodegeneration Due to Alzheimer’s Disease Pathology Using Ex vivo Imaging

Neurofibrillary tangle (NFT) pathology in the medial temporal lobe (MTL) is closely linked to neurodegeneration, and is the early pathological change associated with Alzheimer’s Disease (AD). In this work, we investigate the relationship between MTL morphometry features derived from high-resolution ex vivo imaging and histology-based measures of NFT pathology using a topological unfolding framewor

Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration

Design criteria for tissue-engineered materials in regenerative medicine include robust biological effectiveness, off-the-shelf availability, and scalable manufacturing under standardized conditions. For bone repair, existing strategies rely on primary autologous cells, associated with unpredictable performance, limited availability and complex logistic. Here, a conceptual shift based on the manuf

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The role of African-Caribbean nannies in European households is a painful chapter in Caribbean history for many reasons. Ann M. Beaudhuy was a nanny in Christiansted, St. Croix in what was then the Danish West Indies and which is now the US Virgin Islands. In 1871 she wrote letters that have survived time, transfer and geographical displacement. They contain a rare, personal account of the life an

Versatile microporous polymer-based supports for serial macromolecular crystallography

Serial data collection has emerged as a major tool for data collection at state-of-the-art light sources, such as microfocus beamlines at synchrotrons and X-ray free-electron lasers. Challenging targets, characterized by small crystal sizes, weak diffraction and stringent dose limits, benefit most from these methods. Here, the use of a thin support made of a polymer-based membrane for performing s

Introduction

Globally, the twenty-first century will witness rapid population ageing. Already in 2050, one out of five persons in the world, and one out of three in Europe, is expected to be 60 or over (UN 2015). Moreover, we have entered into a new stage of population ageing in terms of its causes, which have altered its consequences. In the first stage, lasting until the middle of the twentieth century in de

DNA methylation changes associated with prenatal mercury exposure : A meta-analysis of prospective cohort studies from PACE consortium

Mercury (Hg) is a ubiquitous heavy metal that originates from both natural and anthropogenic sources and is transformed in the environment to its most toxicant form, methylmercury (MeHg). Recent studies suggest that MeHg exposure can alter epigenetic modifications during embryogenesis. In this study, we examined associations between prenatal MeHg exposure and levels of cord blood DNA methylation (

Structure and dynamics of dense colloidal ellipsoids at the nearest-neighbor length scale

Anisotropic particles are known to exhibit a richer and more complex phase behavior in comparison to their spherical counterpart. While the majority of the existing studies address structural properties, the dynamic behavior of anisotropic particles is a relatively lesser explored avenue. Using multispeckle ultra-small-angle x-ray photon correlation spectroscopy (USA-XPCS), we have carried out a s

Ligand-independent G protein-coupled estrogen receptor/G protein-coupled receptor 30 activity : Lack of receptor-dependent effects of G-1 and 17b-estradiol

G protein-coupled receptor 30 (GPR30) is a membrane receptor reported to bind 17b-estradiol (E2) and mediate rapid nongenomic estrogen responses, hence also named G protein-coupled estrogen receptor. G-1 is a proposed GPR30-specific agonist that has been used to implicate the receptor in several pathophysiological events. However, controversy surrounds the role of GPR30 in G-1 and E2 responses. We

Profound alterations in brain tissue linked to hypoxic episode after device implantation

To enable authentic interfacing with neuronal structures in the brain, preventing alterations of tissue during implantation of devices is critical. By transiently implanting oxygen microsensors into rat cortex cerebri for 2 h, substantial and long lasting (>1 h) hypoxia is routinely generated in surrounding tissues; this hypoxia is linked to implantation generated compressive forces. Preferential

Toddlers' digital media practices and everyday parental struggles : Interactions and meaning-making as digital media are domesticated

In this article, the Swedish findings from a European comparative study on 0-3-year-old children and their digital lives are presented and discussed in relation to domestication theory, including the concept of moral economy. More specifically, attention is paid to toddler's appropriation of digital technology and the parents' moral struggles: the negotiations between the parents concerning the in

Charge Carrier Diffusion Dynamics in Multisized Quaternary Alkylammonium-Capped CsPbBr3Perovskite Nanocrystal Solids

CsPbBr3 quantum dots (QDs) are promising candidates for optoelectronic devices. The substitution of oleic acid (OA) and oleylamine (OLA) capping agents with a quaternary alkylammonium such as di-dodecyl dimethyl ammonium bromide (DDAB) has shown an increase in external quantum efficiency (EQE) from 0.19% (OA/OLA) to 13.4% (DDAB) in LED devices. The device performance significantly depends on both

Neutral microprotein, a novel human plasma and urinary protein associated with a yellow-brown chromophore. Isolation from protein HC preparations and partial characterization

An apparently novel human plasma and urinary protein of low molecular weight was isolated from several highly purified preparations of protein HC by gel chromatography and high voltage electrophoresis with a yield of about 8 mg/g. The protein has a molecular weight of about 20,000, neutral electrophoretic mobility at pH 6.5 and a high content of half-cystine. It is associated with a yellow-brown c