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Prevalence of endometrioma and deep infiltrating endometriosis at transvaginal ultrasound examination of subfertile women undergoing assisted reproductive treatment

Objective: To estimate the prevalence of endometrioma and deep infiltrating endometriosis (DIE), assessed by systematic transvaginal ultrasound examination, in women with subfertility accepted for their first assisted reproductive treatment and to describe the prevalence of endometriotic lesions in different anatomical locations of the pelvis. Design: Cross-sectional study. Setting: Reproductive M

Giemsa-negative chromosome bands preferentially recombine in cancer-associated translocations and gene fusions

Chromosome abnormalities, in particular translocations, and gene fusions are hallmarks of neoplasia. Although both have been recognized as important drivers of cancer for decades, our knowledge of the characterizing features of the cytobands involved in recombinations is poorly understood. The present study, based on a comparative analysis of 10 442 translocation breakpoints and 30 762 gene fusion

Clinical performance and robustness evaluation of plasma amyloid-β42/40 prescreening

Introduction: Further evidence is needed to support the use of plasma amyloid β (Aβ) biomarkers as Alzheimer's disease prescreening tools. This study evaluated the clinical performance and robustness of plasma Aβ42/Aβ40 for amyloid positivity prescreening. Methods: Data were collected from 333 BioFINDER and 121 Alzheimer's Disease Neuroimaging Initiative study participants. Risk and predictive val

School Nurses’ Perspectives on Health among School-Aged Children and Adolescents During the COVID-19 Pandemic

The aim of this study was to investigate school nurses’ perspectives on students’ health during the COVID-19 pandemic in Sweden in 2021. A cross-sectional survey design was used with school nurses (n = 225) working in schools in Sweden from elementary to upper secondary levels. The Clausson School Nurse Perception Questionnaire was used with two additional questions about the COVID-19 pandemic. Th

How broad is the selfing syndrome? Insights from convergent evolution of gene expression across species and tissues in the Capsella genus

The shift from outcrossing to selfing is one of the main evolutionary transitions in plants. It is accompanied by profound effects on reproductive traits, the so-called selfing syndrome. Because the transition to selfing also implies deep genomic and ecological changes, one also expects to observe a genomic selfing syndrome. We took advantage of the three independent transitions from outcrossing t

Using Novel Molecular-Level Chemical Composition Observations of High Arctic Organic Aerosol for Predictions of Cloud Condensation Nuclei

Predictions of cloud droplet activation in the late summertime (September) central Arctic Ocean are made using κ-Kohler theory with novel observations of the aerosol chemical composition from a high-resolution time-of-flight chemical ionization mass spectrometer with a filter inlet for gases and aerosols (FIGAERO-CIMS) and an aerosol mass spectrometer (AMS), deployed during the Arctic Ocean 2018 e

Affects, emotions and interaction : the methodological promise of video data analysis in peace research

Methodologically, Peace Research has long been dominated by words, numbers, and sometimes images. This article suggests also integrating Video Data Analysis (VDA) into the analytical toolbox of Peace Research so as to explore the potential of the millions of videos of relevance for the study of peace and conflict that can be found online and beyond. The article introduces VDA and shows how the met

Quantum Mechanical Calculations of Redox Potentials of the Metal Clusters in Nitrogenase

We have calculated redox potentials of the two metal clusters in Mo-nitrogenase with quantum mechanical (QM) calculations. We employ an approach calibrated for iron–sulfur clusters with 1–4 Fe ions, involving QM-cluster calculations in continuum solvent and large QM systems (400–500 atoms), based on structures from combined QM and molecular mechanics (QM/MM) geometry optimisations. Calculations on

Law as the Game of Truth in the Case of Xerzan Cemetery

From legal positivism describing law through correctness and certainty to critical studies challenging law's formal truth-seeking by elaborating on its inevitable distance to experience, the relation of law to truth has been long discussed. Adopting a Foucauldian understanding of truth that depends on the deployment of various knowledges, this article focuses on the law's participation in truth-ma

Cross-sectional associations of optimism with artery calcification and function : The SCAPIS study

Background: An increasing amount of research indicates that positive psychological factors, such as optimism, might be beneficial for cardiovascular health. However, most studies have focused on cardiovascular events. The present study aimed to investigate associations between optimism and subclinical outcomes related to cardiovascular health. Methods: This cross-sectional study used data from SCA

Unified method for measuring entropy differences between coexisting surface phases using low energy electron microscopy

We demonstrate the ability of low energy electron microscopy (LEEM) to extract fundamental information in surface phase transitions during in situ observations of complex semiconductor surfaces. We utilize established LEEM techniques and develop a methodology that enables us to calculate the surface entropy difference using only LEEM measurements without the need for external characterization. We

The role of business angels in the new financial landscape

Both access to and use of external sources of finance by entrepreneurial ventures have transformed significantly over the past 10-15 years, which may have induced an important shift in the role of business angels (BAs). In this chapter we elaborate on this changing role of BAs, and in particular on the value creation provided by BAs in the new financial landscape. We propose to reframe the discuss

Noninvasive detection of any-stage cancer using free glycosaminoglycans

Cancer mortality is exacerbated by late-stage diagnosis. Liquid biopsies based on genomic biomarkers can noninvasively diagnose cancers. However, validation studies have reported ~10% sensitivity to detect stage I cancer in a screening population and specific types, such as brain or genitourinary tumors, remain undetectable. We investigated urine and plasma free glycosaminoglycan profiles (GAGomes

Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb

Background: Traumatic peripheral nerve injury is common and incurs significant cost to individuals and society. Healing following direct nerve repair or repair with autograft is slow and can be incomplete. Several bioengineered nerve wraps or devices have become available as an alternative to direct repair or autologous nerve graft. Nerve wraps attempt to reduce axonal escape across a direct repai

Systematic quark/gluon identification with ratios of likelihoods

Discriminating between quark- and gluon-initiated jets has long been a central focus of jet substructure, leading to the introduction of numerous observables and calculations to high perturbative accuracy. At the same time, there have been many attempts to fully exploit the jet radiation pattern using tools from statistics and machine learning. We propose a new approach that combines a deep analyt

Kom med på en flygtur : En reflektion över djursbetydelse för retoriken

I denna korta essä påminner om djurets särskilda ställning i retorikteori, från fabeldjur till en metafor för retorisk kraft. Jag började mitt sökande i klassiska texter som fabler. Här används djur i metaforisk mening för att synliggöra mänskliga dilemman. I vår tid, med ett posthumanistiskt krav på att omvärdera vår relation till det andra räcker dock inte detta antropocentriska perspektiv på dj

Flicker explained : interpretation of the Technical Report IEC 61547

Flicker, or more precisely temporal light modulation (TLM), has re-emerged as a problem with the introduction of LED-based lighting technology. TLM, meaning variations in light intensity over time, may have negative effect on human health, causing annoyance, headaches, eyestrain and migraine. the negative consequences of TLM create an obstacle to broad and rapid adaptation of the new LED-technolog

Inflammatory Animal Models of Parkinson's Disease

Accumulating evidence suggests that microglia and peripheral immune cells may play determinant roles in the pathogenesis of Parkinson's disease (PD). Consequently, there is a need to take advantage of immune-related models of PD to study the potential contribution of microglia and peripheral immune cells to the degeneration of the nigrostriatal system and help develop potential therapies for PD. I