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First study of the two-body scattering involving charm hadrons

This article presents the first measurement of the interaction between charm hadrons and nucleons. The two-particle momentum correlations of pD- and p¯D+ pairs are measured by the ALICE Collaboration in high-multiplicity pp collisions at s=13 TeV. The data are compatible with the Coulomb-only interaction hypothesis within (1.1-1.5)σ. The level of agreement slightly improves if an attractive nucleo

A scoring system for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas: a multicenter EUROPEAN validation

Purpose: A preoperative estimate of the risk of malignancy for intraductal papillary mucinous neoplasms (IPMN) is important. The present study carries out an external validation of the Shin score in a European multicenter cohort. Methods: An observational multicenter European study from 2010 to 2015. All consecutive patients undergoing surgery for IPMN at 35 hospitals with histological-confirmed I

High Gas-Phase Methanesulfonic Acid Production in the OH-Initiated Oxidation of Dimethyl Sulfide at Low Temperatures

Dimethyl sulfide (DMS) influences climate via cloud condensation nuclei (CCN) formation resulting from its oxidation products (mainly methanesulfonic acid, MSA, and sulfuric acid, H2SO4). Despite their importance, accurate prediction of MSA and H2SO4 from DMS oxidation remains challenging. With comprehensive experiments carried out in the Cosmics Leaving Outdoor Droplets (CLOUD) chamber at CERN, w

A 1.7-6.4 GHz fourth-order RF filter with 1-40% fractional bandwidth in 22-nm FDSOI

The rise of 5G technology leads to a boom in the demand for widely available wireless connectivity while requiring telecommunication networks to improve spectral efficiency and deploy dynamic spectrum sharing (DSS) and carrier aggregation (CA). This imposes more stringent intermodulation test scenarios and blocking requirements on RF transceivers. In addition, they are required to be programmable

Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis

The relationships between structure and function in human knee femoral cartilage are not well-known at different stages of osteoarthritis. Thus, our aim was to characterize the depth-dependent composition and structure (proteoglycan content, collagen network organization and collagen content) of normal and osteoarthritic human femoral condyle cartilage (n = 47) and relate them to their viscoelasti

Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning

Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths. OPs inhibit the enzyme acetylcholinesterase (AChE), which leads to impairment of the central- and peripheral nervous system. Current standard of care (SOC) alleviates acute neurologic-, cardiovascular- and respi

Investigating pathways for predisposing, enabling and need factors in predicting the use of STI/HIV-testing services among Syrian and Iraqi migrants in Scania, Sweden – a cross-sectional study with directed acyclic graphs for modelling pathways to testing

Background: Some groups of migrants have increased vulnerability to Sexually Transmitted Infections (STI) and Human Immunodeficiency Virus (HIV) transmission partly due to a lower uptake of disease preventive activities targeting the general population in receiving country. Limited access to economic and social resources and poor language skills may exacerbate exposure to sexual risks and utilizat

A micromechanically motivated multiscale approach for residual distortion in laser powder bed fusion processes

For the broader industrial usage of metal additive manufactured parts, especially made by laser powder bed fusion, a better prediction and understanding of the warpage and of eigenstresses within the final part are necessary. Due to the diverse and sophisticated metallurgical and thermal processes during production, physically motivated simulations are rather complex and time consuming. Therefore,

Context-based sensing of orthosomycin antibiotics by the translating ribosome

Orthosomycin antibiotics inhibit protein synthesis by binding to the large ribosomal subunit in the tRNA accommodation corridor, which is traversed by incoming aminoacyl-tRNAs. Structural and biochemical studies suggested that orthosomycins block accommodation of any aminoacyl-tRNAs in the ribosomal A-site. However, the mode of action of orthosomycins in vivo remained unknown. Here, by carrying ou

Age and gender relations on LinkedIn pages of global staffing agencies

This study investigates the ways in which age and gender play out on the LinkedIn pages of global staffing agencies through an intersectionality lens. A discourse analysis of 437 LinkedIn posts (including visual images, captions, and comments) was conducted. This study found that the corporate discourse of diversity shaped the ways that age and gender were represented. The portrayals of age and ge

Thoughts on the end of life in patients with oxygen-dependent chronic obstructive pulmonary disease : A qualitative interview study

Aim: The aim of the study was to deepen the current knowledge of how patients with chronic obstructive pulmonary disease and long-term oxygen treatment think about and expect end-of-life. Design: A qualitative design was used. Methods: A purposeful sample of 19 patients with oxygen-dependent chronic obstructive pulmonary disease was obtained from the Swedish National Registry on Respiratory Failur

Some Results on Oscillation Stability in Multi-Mode Harmonic Oscillators

We study the stability of oscillation in two different multi-mode harmonic oscillators by means of Barkhausen’s criterion, involving a minimum of mathematical machinery in favor of a more intuitive, circuit-based approach. The results of the theoretical analysis match very closely those obtained through transient simulations, confirming occasionally surprising outcomes of the latter.

Fast Electromagnetic Validations of Large-Scale Digital Coding Metasurfaces Accelerated by Recurrence Rebuild and Retrieval Method

The recurrence rebuild and retrieval method (R3M) is proposed in this paper to accelerate the electromagnetic (EM) validations of large-scale digital coding metasurfaces (DCMs). R3M aims to accelerate the EM validations of DCMs with varied codebooks, which involves the analysis of a group of similar but not identical structures. The method transforms general DCMs to rigorously periodic arrays by r

Can heavy metal pollution induce soil bacterial community resistance to antibiotics in boreal forests?

The emergence of microbial antibiotic resistance is a central threat to global health, food security, and development. It has been shown that heavy metal pollution can give rise to microbial resistance to antibiotics, but how wide-spread this phenomenon is remains an open question that urgently needs filling to enable appropriate environmental risk assessments. Here, we determined whether long-ter