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Measurement of four-jet differential cross sections in root s=8 TeV proton-proton collisions using the ATLAS detector

Differential cross sections for the production of at least four jets have been measured in proton-proton collisions at root s = 8 TeV at the Large Hadron Collider using the ATLAS detector. Events are selected if the four anti-k(t) R = 0.4 jets with the largest transverse momentum (p(T)) within the rapidity range vertical bar y vertical bar < 2 : 8 are well separated (Delta R-4j(min) > 0.65), all h

Spherical and Deformed High-spin states in 38Ar

Excited states in Ar-38 have been investigated by means of the heavy-ion fusion-evaporation reaction Si-28 +O-16. The level scheme reveals a subtle interplay between spherical, deformed, and superdeformed shapes. Large-scale shell-model calculations in the sd-fp space are invoked to study the microscopic aspects of deformation and shape changes.

Variation in BRCA1 cancer risks by mutation position

Previous studies have reported variation in BRCA1 breast and ovarian cancer risks with mutation position, suggesting that mutations toward the 3' end of the gene are associated with lower ovarian cancer risks. We evaluated the evidence for genotype-phenotype correlations in 356 families with protein-truncating BRCA1 mutations. In contrast to previous reports, the ovarian:breast cancer ratio associ

Clinicians' management strategies for patients with dyspepsia: a qualitative approach

Background: Symptoms from the upper gastrointestinal tract are frequently encountered in clinical practice and may be of either organic or functional origin. For some of these conditions, according to the literature, certain management strategies can be recommended. For other conditions, the evidence is more ambiguous. The hypothesis that guided our study design was twofold: Management strategies

Musical learning in a cross-cultural setting: a case study of Gambian and Swedish adolescents in interaction

This article presents a study investigating how adolescents from Sweden and the Gambia learned music while interacting with each other in a concert project conducted in the Gambia. The main aim is to explore in what ways adolescents acquire music and to analyse it in a context of cultural identity. A sociocultural and ethnomusicological approach was employed, drawing on field studies and interview

Accidental falls, health-related quality of life and life satisfaction: A prospective study of the general elderly population.

As the physical consequences of accidental falls in the elderly are well-researched, the long-term associations between falls and quality of life and related concepts are less known. The aim of this study was to prospectively examine the long-term relations between falls and health-related quality of life (HRQoL) and life satisfaction (LS) over six years in the general elderly population. One thou

The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: A retrospective analysis of the FEATHER study.

Patients treated with clopidogrel who have higher body size exhibit greater platelet reactivity than patients with lower body size. In a retrospective analysis of the FEATHER trial, we examined the relationship between platelet response to thienopyridines clopidogrel 75mg (Clop-75), prasugrel 5mg (Pras-5), and prasugrel 10mg (Pras-10) using 3 body size indices: body weight (BW), body mass index (B

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Studies of determinants of development of inhibitory antibodies to factor VIII in people with hemophilia A indicate a complex process involving multiple factors. The Hemophilia Inhibitor Genetics Study Combined Cohort was formed to extend understanding of the genetic background of risk. The study group contains 833 subjects from three independent cohorts: brother pairs and singletons with and with

Body mass index (BMI) and dental caries in 5-year-old children from southern Sweden.

OBJECTIVES: The aim of the present survey was to study the association between dental caries and body mass index (BMI) in Swedish preschool children (born in 1999). METHODS: A population-based and cross-sectional study design was used comprising all 920 5-year-old children in a defined area in and around the city of Lund. Anthropometric measures for the calculation of BMI were retrieved for each

Searching for doubly charged vector bileptons in the golden channel at the LHC

In this paper we investigate the LHC potential for discovering doubly charged vector bileptons considering the measurable process p, p -> e(-/+) e -/+ mu(+/-) mu(+/-) X. We perform the study using four different bilepton masses and three different exotics quark masses. Minimal LHC integrated luminosities needed for discovering and for setting limits on bilepton masses are obtained for both 7 and 1

Reducing disaster risks 1980-2010: Some reflections and speculations

Through personal reflections on themes covering past experiences, the author considers selected experiences of disaster risk management (DRM) that span 30 years of DRM, and makes some speculations concerning the future, and ponders whether within the selected themes the future looks positive or negative. The observations begin with some memories of the Ocho Rios Conference: a multi disciplinary ex

Periostin Secreted by Mesenchymal Stem Cells Supports Tendon Formation in an Ectopic Mouse Model

True tendon regeneration in human patients remains a vision of musculoskeletal therapies. In comparison to other mesenchymal lineages the biology of tenogenic differentiation is barely understood. Specifically, easy and efficient protocols are lacking that might enable tendon cell and tissue differentiation based on adult (stem) cell sources. In the murine mesenchymal progenitor cell line C3H10T1/

Influence of anisotropic grain boundary properties on the evolution of grain boundary character distribution during grain growth - a 2D level set study

The present study elaborates on a 2D level set model of polycrystal microstructures that was recently established by adding the influence of anisotropic grain boundary energy and mobility on microstructure evolution. The new model is used to trace the evolution of grain boundary character distribution during grain growth. The employed level set formulation conveniently allows the grain boundary ch

Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease.

In adult mammals, neural progenitors located in the dentate gyrus retain their ability to generate neurons and glia throughout lifetime. In rodents, increased production of new granule neurons is associated with improved memory capacities, while decreased hippocampal neurogenesis results in impaired memory performance in several memory tasks. In mouse models of Alzheimer's disease, neurogenesis is