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Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures

Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the human brain. Here we investigated whether neuronal cultures derived from human induced pluripotent stem cells (hiPSCs) feature key advantages compared with rodent primary cultures. Using calcium fluorescence imaging, we tracked

Microbial ecosystem analysis of biochar-enriched soil in Kenya using microfluidic soil models

Healthy soil is rich in diverse microbial life, and a healthy microbial ecosystem is crucial for any well-functioning agriculture. Soil microbes are essential for organic decomposition and nutrient recycling in the soil, which make nutrients available for agricultural crops. Biochar-enrichment of soil has previously been found to increase crop yields in Kenya, and could potentially be a self-relia

Getting at the Experience of Confinement in Detention

A distinguishing feature of youth detention homes—and any other prisonlike institution—is the fact that inmates cannot just leave. They might escape, and there are ways to be transferred, enjoy an excursion, and get permission for home visits, but typically the young people in this case are supposed to remain within their given institution. I have been eager to not only depict this feature of fielA distinguishing feature of youth detention homes—and any other prisonlike institution—is the fact that inmates cannot just leave. They might escape, and there are ways to be transferred, enjoy an excursion, and get permission for home visits, but typically the young people in this case are supposed to remain within their given institution. I have been eager to not only depict this feature of fiel

“Therapy without a therapist?” The experiences of adolescents and their parents of online behavioural activation for depression with and without therapist support

Behavioural Activation (BA) is an established treatment for adults with depression, and research on BA for adolescents is promising. However, there is a knowledge gap in terms of the experiences of adolescents and their parents BA for depression delivered online. Furthermore, there have been no previous studies conducted on the experiences of respondents with regard to the role of the therapist in

MALMÖS ARBETSMARKNAD OCH ARBETSLÖSHET. Vad förklarar skillnaderna mot riket?

Sammanfattning av rapportens främsta resultat• De senaste årens negativa arbetsmarknadsutveckling för Malmö tycks delvis bero på förändringar iarbetspendling till Danmark.• Gapet i arbetslöshet mellan Malmö och riket kan förklaras utifrån skillnader i befolkningens demografi och utbildningsnivå, invandrartäthet och näringslivets sammansättning.• Malmös stora andel av befolkningen som bor i invandr

The Doll’s Marriage: An Ethnographic Encounter with Rural Children and Childhood

The pictorial representations of activities and social interactions provide the researcher with a sensory experience both during and after the fieldwork. I had interesting encounters with children and families during my ethnographic research on the social value of the child in rural Punjab (2019). Some of these encounters were also photographed. Attending a doll's marriage ceremony was one of thos

Regional differences in the quality of maternal and neonatal care during the COVID-19 pandemic in Portugal : Results from the IMAgiNE EURO study

Objective: To compare women's perspectives on the quality of maternal and newborn care (QMNC) around the time of childbirth across Nomenclature of Territorial Units for Statistics 2 (NUTS-II) regions in Portugal during the COVID-19 pandemic. Methods: Women participating in the cross-sectional IMAgiNE EURO study who gave birth in Portugal from March 1, 2020, to October 28, 2021, completed a structu

Flame front visualization in highly turbulent jet flames using CH3 photofragmentation laser-induced fluorescence

Flame front visualization using methyl photofragmentation laser-induced fluorescence (CH3-PF-LIF) was demonstrated in turbulent premixed methane/air flames. A pump–probe method was used to detect CH3, where CH3 was first photolyzed to CH (X2П) fragments using a pump laser (212.8 nm), and the fragments were subsequently excited to CH in the C2Σ+ state by a probe laser at 314.4 nm. By detecting fluo

Ambulanssjuksköterskans beslutsfattande vid prehospitala hjärtstopp

Abstrakt Bakgrund: Vid ett prehospitalt hjärtstopp där ambulans har tillkallats beslutar ambulanssjuksköterskan om att påbörja, avstå eller avsluta hjärt- och lungräddning (HLR). Arbetet i ambulanssjukvården ställer höga krav på att ambulanssjuksköterskan ska ha förmågan att fatta etiskt svåra beslut i komplexa vårdsituationer. Syfte: Syftet var att undersöka ambulanssjuksköterskans beslutsfatta

Att göra livet (över)levbart : Transpersoners ontiska, relationella och reflekterande arbete för att skapa minoritetsro och hantera utsatthet i vardagen

Transgender people report significantly poorer mental health than cisgender people. In psychological research, these health disparities are explained by theories of minority stress and microaggressions, while other disciplines use theories on normativity, livability, affective work, world making and utopias. Such theories are seldom picked up by psychologists even though they could serve to help p

Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis

Purpose: Despite the significant role of varicocele in the pathogenesis of male infertility, the impact of varicocele repair (VR) on conventional semen parameters remains controversial. Only a few systematic reviews and meta-analyses (SRMAs) have evaluated the impact of VR on sperm concentration, total motility, and progressive motility, mostly using a before-after analytic approach. No SRMA to da

A model of reactive settling of activated sludge : Comparison with experimental data

A non-negligible part of the biological reactions in the activated sludge process for treatment of wastewater takes place in secondary settling tanks (SST) that follow biological reactors. It is therefore of interest to develop models of so-called reactive settling that describe the spatial variability of reaction rates caused by the variation of local concentration of biomass due to hindered sett

Why Russia needs decolonisation for its future democratisation

Ukraine’s recent success on the battlefield has encouraged discussion on potential changes to Russia’s political setup. While a new leader would be needed, more fundamental change would be required if the country is to embark on a path towards democracy. The key issue lies in Moscow’s relations with its periphery, an exploitative relationship that has persisted for centuries.The war in Ukraine has

Water quality modeling of a eutrophic drinking water source : Impact of future climate on Cyanobacterial blooms

Cyanobacterial blooms are becoming more frequent in freshwater sources, causing concern throughout the world. Cyanobacterial blooms affect human health and the entire environment. Numerical modeling is an effective tool for investigating aquatic systems. In this study, a 3D hydrodynamic and water quality (ecological) model was used to simulate eutrophication of a drinking water source, Lake Vomb,

An LO phase shifter with frequency tripling and phase detection in 28 nm FD-SOI CMOS for mm-wave 5G transceivers

This paper presents an LO phase shifter with frequency tripling for 28-GHz 5G transceivers. The phase shifting and frequency tripling are achieved using an injection-locked oscillator and injection-locked frequency tripler, respectively. A phase detector based on third harmonic mixing is also implemented and is used to detect the applied phase shift, supporting automatic calibration of the phase s

The impact of previous health on the mortality after aneurysmal subarachnoid hemorrhage : analysis of a prospective Swedish multicenter study

Purpose: There is an an increasing awareness of the importance of health and lifestyle for stroke diseases like spontaneous subarachnoid hemorrhage (SAH). However, the importance of pre-existing medical conditions for clinical course and mortality after SAH has not been studied. The aim of the present study was to identify pre-existing conditions contributing to mortality after SAH. Methods: Data