Aim: To investigate the release of hydrophobic and hydrophilic substances from tablets containing Pemulen and Carbopol as excipients. Method: The dissolution patterns of a hydrophobic (diazepam) and a hydrophilic active substance (midodrine-HCl) from different tablet formulations containing a nonmodified polyacrylic microgel (Carbopol 981 F) or a hydrophobically modified polyacrylic microgel (Pemu

Objective-Pleiotropic atheroprotective effects of HMG-CoA reductase inhibitors may be mediated on the level of vascular gene transcription. The aim of this study was to characterize the effects of statins on the activation of transcription factors known to regulate inflammation and cell proliferation/differentiation. Methods and Results-Simvastatin, atorvastatin, and lovastatin (0.1 to 10 mumol/L)

In the present scenario, fats and oil modification is one of the prime areas in food processing industry that demands novel economic and green technologies. In this respect, tailored vegetable oils with nutritionally important structured triacylglycerols and altered physicochemical properties have a big potential in the future market. In this context, it is well established that lipases especially

A crucial aspect of empirical research based on the vector autoregressive (VAR) model is the choice of the lag order, since all inference in the VAR model is based on the chosen lag order. Here, a new information criterion is introduced for this purpose. The conducted Monte Carlo simulation experiments show that this new information criterion performs well in picking the true lag order in stable a

Controlled growth of nanowires is an important, emerging research field with many applications in, for example, electronics, photonics, and life sciences. Nanowires of zinc blende crystal structure, grown in the left fence111right fenceB direction, which is the favoured direction of growth, usually have a large number of twin-plane defects. Such defects limit the performance of optoelectronic nano

A mobile lidar system was used in remote imaging laser-induced breakdown spectroscopy (LIBS) and laser-induced fluorescence (LIF) experiments. Also, computer-controlled remote ablation of a chosen area was demonstrated, relevant to cleaning of cultural heritage items. Nanosecond frequency-tripled Nd:YAG laser pulses at 355 nm were employed in experiments with a stand-off distance of 60 meters usin

Alkyl-modified silicon nanocrystallites are efficient fluorophores which are of interest for fundamental spectroscopic studies and as luminescent probes in biology because of their stability in aqueous media. In this work we have investigated these particles using scanning tunneling microscopy, synchrotron-radiation excited photoemission, and x-ray excited optical luminescence (XEOL). During the c

Purpose and method: A review article concerning orthopaedic treatment and rehabilitation of displaced femoral neck fractures, focusing on evidence-based knowledge. Results: Properly performed randomized controlled studies comparing internal fixation and primary arthroplasty provides the best basis to decide which method should be used. During the last decade, several such studies have been publish

Study objectives: To identify and quantify a hypothesised collective effect of the neighbourhood on individual use of anxiolytic-hypnotic drugs (AHD). To analyse the general impact of neighbourhood social participation on use of AHD, adjusting for individual characteristics. Design: Cross sectional analysis performed by multilevel logistic regression with women at the first level and neighbourhoo

It is pointed out that the triaxial bands in Nd138-140 and in the Lu/Er nuclei can be understood from the same shell structure effects. Two of the bands in Nd-138, interpreted as signature partners, exhibit a crossing at high spins with a signature splitting which is strongly reduced above the crossing. This behavior is unique among the yrast and close-to-yrast configurations, revealing the mechan

The United Nations Conference on Sustainable Development, held in June 2012 in Rio de Janeiro, was probably the largest event in a long series of megasummits on environmental protection and sustainable development. Roughly 44 000 participants descended on Rio de Janeiro to take part in ten days of preparatory committee meetings, informal consultations, side events, and the actual conference. Yet d

A more detailed mechanistic understanding of how low molecular weight (MW) carbon (C) substrates are mineralized within the rhizosphere by soil microbial communities is crucial to accurately model terrestrial C fluxes. Currently, most experiments regarding soil C dynamics are conducted ex-situ (laboratory) and can fail to account for key variables (e.g. temperature and soil water content) which va

Patients with hazardous alcohol intake are overrepresented in emergency departments and surgical wards. These patients have an increased risk of postoperative complications with prolonged hospital stays and admissions to intensive care unit after surgery. In elective surgery, preoperative alcohol cessation interventions can reduce postoperative complications, but no studies have investigated the e

I reconstruct Bruno Latour's ideas about science and religion and compare them to Ian G. Barbour's and Mikael Stenmark's models, as well as to the discussion of technology and religion developed by John C. Caiazza and Antje Jackelen. I show how using "Latour's App" enlightens some aspects of said models which Barbour and Stenmark themselves were seemingly struggling with, and that Caiazza's and Ja