Popular Abstract in Swedish Två händelser i tumörutvecklingen för en tumörcell är att erhålla okontrollerad celltillväxt och invasiva egenskaper. Detta tillåter tumöran att växa in i den omkringliggande vävnaden. I denna avhandling har vi specifikt studerat p16 och ERK1/2 med speciell fokus på förhållandet mellan invasion och proliferation i hudcancer och bröstcancer. Basalcellscancer har ett disTwo key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. We here specifically studied p16 and ERK1/2 with special focus on and the relation to proliferation and invasion in non-melanoma skin cancer and in breast cancer. In a model system

A combined quantum mechanical-statistical mechanical method has been used to study the behavior of the hydroxyl ion in water. The system is divided into three parts, a quantum core (the ion), 89 classical water molecules, and a dielectric continuum. The water molecules are represented using a polarizable potential. The first solvation shell consists of four water molecules, two linked by hydrogen

Charge pair photogeneration was investigated by ultrafast absorption spectroscopy for different excitation photon energies in poly[3-(2(')-methoxy-5(')octylphenyl)thiophene] (POMeOPT) film with and without an external electric field. Electric field-assisted charge pair photogeneration in POMeOPT occurs from vibrationally relaxed singlet excitons during their entire lifetime and charge pair formati

Recension av Roger Gyllin, Ingvar Svanberg & Ingmar Söhrman (red.); Bröd och salt. Svenska kulturkontakter med öst. En vänbok till Sven Gustavsson.

Popular Abstract in Swedish Hårdvara och algoritmer för ett inbyggt videoövervakningssystem presenteras i denna avhandling. För att verifiera systemet så har en prototyp byggts.The demands on video surveillance systems are rapidly increasing regarding parameters such as frame rate and resolution. Furthermore, with an ever increasing number of video streams, an automated process for extracting relevant information is required. Due to the large amount of input data and the computational complexity of the algorithms, software implementations are not sufficient to sustain re

Characterization of soil respiration rates and δ13C values of soil-respired CO2 are often based on measurements at a particular time of day. A study by Gower et al. (2001) in a boreal forest demonstrated diurnal patterns of soil CO2 flux using transparent measurement chambers that included the understory vegetation. It is unclear whether these diurnal patterns were solely the result of photosynthe

The Wilms' tumor gene 1 (WT1) protein is a transcriptional regulator that is highly expressed in immature hematopoietic progenitor cells and in the majority of patients with acute and chronic myeloid leukemia. However, it is still unclear how WT1 exerts its function(s) in hematopoietic cells. The aim of this work was to investigate the function of WT1 as a transcription factor in human hematopoiet

Popular Abstract in Swedish Faderskap är en familjepolitisk angelägenhet där staten går in och intervenerar och på så sätt fostrar fäder. Tyngdpunkten ligger på att uppmuntra fadersnärvaro och att förmå frånvarande fäder att ta ansvar för sina barn. Detta ger oss en bild av vad som uppfattas som bra fäder och vad som avviker från normen. Den sociala barnavården är en kontext som verkar inom den soThis dissertation deals with fathers of children subjected to child welfare investigations. They are "fathers called into question" and their fatherhood is not very much investigated so far. The dominating picture is that the fathers are absent, to their children as well as in research and social work literature. Two Swedish contexts are presented. These represent different interpretations of "the

Adolescence is a period when teens normally revolt against being dependent. For teens with asthma this period may be even more difficult to deal with, as they also have to deal with their illness. Since few studies describe this phenomenon, the aim of this study was to provide a theoretical understanding of how teens with asthma manage their everyday life in relation to their disease. A grounded t

Three new species, i.e. Hieracium evae I Tyler, Hieracium jonsbergense T. Tyler, Hieracium subnitidum Dahlst. ex T. Tyler, and one variety, i.e. H. ravidum Brenn. var. exaltifrons T. Tyler var. nov. are described. Hieracium myrtillinum (Johanss. ex Dahlst.) T. Tyler comb. nova is proposed. All are based on material collected in the SE Swedish provinces Gotland and Ostergotland.

The capacity of downlink cellular multiple-input multiple-output (MIMO) systems, where co-channel interference is the dominant. channel impairment, is investigated in this paper, mainly from a signal-processing perspective. Turbo space-time multiuser detection (ST MUD) is employed for intracell communications and is shown to closely approach the ultimate capacity limits in Gaussian ambient noise f

We found that engagement of beta (2) integrins on human neutrophils induced activation of RhoA, as indicated by the increased ratio of GTP:GTP + GDP recovered on RhoA and translocation of RhoA to a membrane fraction. The clustering of beta (2) integrins also induced a time-dependent increase in GDP bound to RhoA, which correlated with beta (2) integrin-induced activation of p190RhoGAP. The activat