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Outcome of follow-up computed tomography of suspected occult scaphoid fracture after normal radiography

Purpose: To evaluate the rate of missed scaphoid fractures on follow-up computed tomography (CT) for suspected occult scaphoid fracture after normal radiography with residual radial-sided wrist pain. Methods: In a retrospective analysis, wrist CT during a five-year period was analyzed. The CT examinations and radiological reports were re-evaluated. Available clinical findings and radiologic follow

A Window to the Past: Living standards in historical perspective

Real wages are a convenient, useful, and powerful way to learn how life was like in the past. In this chapter we start by reviewing the methodology behind real wage estimations and their history. Then we look at the how real wages have contributed to shedding light on major issues in economic history such as the onset of modern economic growth, the Great Divergence, and colonialism in the Americas

Prediction of survival after pancreatoduodenectomy for distal cholangiocarcinoma : independent external validation of a prognostic model for 3-year overall survival in Sweden

Objectives: The only treatment with curative potential for distal cholangiocarcinoma (dCCA) is radical surgery which can be complemented with adjuvant chemotherapy. The aim of the present study was to perform an independent external validation of a prognostic model for 3-year overall survival based on routine clinicopathological variables for patients treated with pancreatoduodenectomy for dCCA. M

Impact of mild hypercapnia on renal function after out-of-hospital cardiac arrest

Background: Acute kidney injury (AKI) is a serious complication of out-of-hospital cardiac arrest (OHCA). Post-resuscitation cardiogenic shock (CS) is a key contributing factor. Targeting a higher arterial carbon dioxide tension may affect AKI after OHCA in patients with or without CS. Methods: Pre-planned exploratory study of a multi-national randomised trial comparing targeted mild hypercapnia o

Olfaction with legs—Spiders use wall-pore sensilla for pheromone detection

The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insects. In contrast, little is known about the chemosensory world of spiders and nothing about how they perform olfaction despite their important ecological role. The orb-weaving spider Argiope bruennichi lends itself to an in-depth study on olfaction as it

The Distinct Seasonality of Early Modern Casual Labor and the Short Durations of Individual Working Years: Sweden 1500–1800

This paper makes use of nearly 25,000 observations representing over 95,000 paid workdays across over 300 years to investigate individual work patterns, work availability, and the changes in work seasonality over time. This sample is comprised of workers in the construction industry, and includes unskilled men and women as well as skilled building craftsmen – the industry which is often used to es

Impact of smoking status on engagement in remote symptom monitoring after oncologic surgery : Implications for symptom management and readmission rates

Background: Remote symptom monitoring (RSM) is an evidence-based strategy shown to mitigate postoperative morbidity; however, platform engagement is required to benefit from RSM. Patients who report current smoking are at high risk for postoperative complications, but it is unknown whether smoking status influences engagement with RSM, symptom severity, or unanticipated acute care visits. Methods:

Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype

The scarcity of hematopoietic stem cells (HSCs) restricts their use in both clinical settings and experimental research. Here, we examined a recently developed method for expanding rigorously purified murine HSCs ex vivo. After 3 weeks of culture, only 0.1% of cells exhibited the input HSC phenotype, but these accounted for almost all functional long-term HSC activity. Input HSCs displayed varying

Long Term Outcomes of Endovascular Repair for Blunt Traumatic Aortic Injury : A Twenty Year Multicentre Follow Up Study

Objective: This retrospective, multicentre, observational study analysed patients who underwent endovascular repair for blunt traumatic aortic injury (BTAI) at four tertiary trauma referral centres over twenty years. It aimed to determine early and long term survival, to analyse aortic and device related complications, and to assess the re-intervention rate after endovascular repair for BTAI. Meth

Incidence of Clinically Diagnosed Psoriatic Arthritis in Sweden

Objective. Prior incidence estimates of psoriatic arthritis (PsA) vary considerably. We aimed to assess the annual incidence of clinically diagnosed PsA among adults in Sweden in 2014-2016, overall and stratified by age/sex/education/geography, and to investigate potential time trends in incidence in 2006-2018. Use of disease-modifying antirheumatic drugs (DMARDs) during the 2 years after diagnosi

Healthcare Professionals’ Ratings and Views of Person-Centred Care in the Context of Allogeneic Hematopoietic Stem Cell Transplantation

Introduction: Allogeneic stem cell transplantation (allo-HCT) involves a long trajectory with high risk of complications. In person-centred care (PCC), patients’ needs, resources and the care relationship are central to the care process. Healthcare professionals’ (HCPs) ratings of PCC have not previously been investigated in this context. Objectives: The aim of this study was to investigate health

Macroecological predictors to determine future refuges of Luciobarbus species in the Tigris–Euphrates basin : Rethinking conservation strategies and management

Freshwater ecosystems, being highly susceptible to the impacts of climate change, experience a greater influence than terrestrial and marine ecosystems. Hence, by identifying the regions that will be most affected by climate change in the future, managers can implement more efficient and effective measures to protect them. In this study, we utilized six Luciobarbus species residing at the southern

Generalized two-parameter estimators in the multinomial logit regression model : methods, simulation and application

In this article, we propose generalized two-parameter (GTP) estimators and an algorithm for the estimation of shrinkage parameters to combat multicollinearity in the multinomial logit regression model. In addition, the mean squared error properties of the estimators are derived. A simulation study is conducted to investigate the performance of proposed estimators for different sample sizes, degree

A new class of efficient and debiased two-step shrinkage estimators : method and application

This paper introduces a new class of efficient and debiased two-step shrinkage estimators for a linear regression model in the presence of multicollinearity. We derive the proposed estimators’ mean square error and define the necessary and sufficient conditions for superiority over the existing estimators. In addition, we develop an algorithm for selecting the shrinkage parameters for the proposed

Climate change impact uncertainty assessment and adaptations for sustainable maize production using multi-crop and climate models

Future climate scenarios are predicting considerable threats to sustainable maize production in arid and semi-arid regions. These adverse impacts can be minimized by adopting modern agricultural tools to assess and develop successful adaptation practices. A multi-model approach (climate and crop) was used to assess the impacts and uncertainties of climate change on maize crop. An extensive field s