Recently, we reported a positive correlation between Klotho, as an anti-aging protein, and the total antioxidant capacity (TAC) in cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients. However, there is no information about the Klotho and TAC changes within the central nervous system (CNS). Thus, the current study aimed to employ an experimental autoimmune encephalomyelitis (EAE) model in

Background: We have previously performed a Genome Wide Association and linkage study that indicated a new disease triggering mechanism involving amino acid metabolism and nutrient sensing signaling pathways. Objective: The aim of this study was to investigate if plasma amino acid levels differed among children with celiac disease compared with disease controls. Materials and methods: Fasting plasm

Journal of Thrombosis and Haemostasis DOI: 10.1111/j.1538-7836.2011.04380

The total resources form copper, zinc and lead was estimated from a reworking of the literature. The data was used as input to the integrated systems dynamics model BRONZE, and used to estimate the global supply of these metals and the by-products antimony, indium, germanium, tellurium, cadmium, bismuth and selenium. The runs show that copper, zinc and lead go through peak production around 2050 a

Dans la société contemporaine, l’accès et la dépendance accrus aux technologies numériques ont permis l'externalisation de la mémoire, ce qui représente un problème particulièrement important dans le contexte éducatif. Cet article cherche à rendre visible la façon dont les relations changent entre la recherche et la mémorisation de l'information à l’école, à partir d’une enquête menée auprès d’ens

DN DEBATT 22/3. Det svenska valet hotas av digitala påverkansoperationer där falska robot-konton och så kallade ”dark ads” kan dränka det politiska samtalet. Vi utmanar nu riksdagspartierna: Ge ett enkelt löfte till väljarna om att ni inte kommer att använda er av oetiska metoder på nätet, skriver Jonas Andersson Schwarz, Stefan Larsson och Anders Mildner.

Objective: The aim of this study was to investigate the awareness of palliative care (PC) in a general Swedish population. Design: We developed an e-survey based on a similar study conducted in Northern Ireland, consisting of 10 questions. Closed questions were primarily analyzed using descriptive statistics. Open questions were subject to inductive qualitative analysis. Subjects: The study utiliz

The spectral characters of the electroencephalogram activity (EEG) is of interest both in studies of the EEG and in estimation oI Evoked Potentials. Often parametric methods assume an underlying model like AR or ARMA [1]. To avoid the model assumption a non-parametric multiple-window meihod for spectral estimation is used in this paper. The method uses Slepian's Discrete Prolate Spheroidal Wave Fu

Nursing in hypertension care comprises counselling about lifestyle changes, blood pressure measurement, and being a translator for the physician. For the patient, changing lifestyle means performing self-care. As not much in the form of research and guidelines for nurses is available, a middle-range theory of nursing in hypertension care was developed to guide nurses in their practice, in order to

Agricultural intensification is one of the main causes for the current biodiversity crisis. While reversing habitat loss on agricultural land is challenging, increasing the farmland configurational heterogeneity (higher field border density) and farmland compositional heterogeneity (higher crop diversity) has been proposed to counteract some habitat loss. Here, we tested whether increased farmland

Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide implicated in a wide range of functions, such as nociception and in primary headaches. Regarding its localization, PACAP has been observed in the sensory trigeminal ganglion (TG), in the parasympathetic sphenopalatine (SPG) and otic ganglia (OTG), and in the brainstem trigeminocervical complex. Immunohistochemistry has shown

Background: Autoimmune (type 1) diabetes (T1D) is a frequent chronic disease in children and adolescents globally. Gestational enterovirus (EV) infections have been associated with an increased risk for T1D in the offspring. We test the hypothesis that EV infections during the first trimester were associated with beta cell autoantibodies in mothers of children who developed islet autoantibodies be

Den här avhandlingen undersöker staters interaktion som en social läroprocess, i syfte att förstå hur stater lär sig om miljönormer. Detta sker genom en konstruktivistisk ansats och mer specifikt ett roll-teoretiskt perspektiv, där en roll förstås som statens repertoar av beteende, jämsides dess funktion i en social interaktionskontext. Rollen formas av ego- och alterförväntningar, det vill säga bThis study investigates state interaction as a social learning process, where the ultimate aim is to enhance an understanding on how states learn of environmental norms. An entry into the domain on such learning processes is offered through a Constructivist approach and more specifically through the employment of a role theoretical perspective; a role here is signified as a state's repertory of be

A search for doubly charged Higgs bosons with pairs of prompt, isolated, highly energetic leptons with the same electric charge is presented. The search uses a proton–proton collision data sample at a centre-of-mass energy of 13 TeV corresponding to 36.1 fb - 1 of integrated luminosity recorded in 2015 and 2016 by the ATLAS detector at the LHC. This analysis focuses on the decays H± ±→ e±e±, H± ±→