The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a

Population-based registries may provide data complementary to that from basic science and clinical intervention studies, all of which essential for establishing recommendations for the management of patients in the real world. The same quality criteria apply for the evidence-based label, and both high representation and good data quality are crucial in registry studies. Registries with high covera

The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatment despite the use of a barrier. This study was performed to examine the effect

Gene therapy using recombinant adeno-associated viral vectors overexpressing neuropeptide Y in the hippocampus exerts seizure-suppressant effects in rodent epilepsy models and is currently considered for clinical application in patients with intractable mesial temporal lobe epilepsy. Seizure suppression by neuropeptide Y in the hippocampus is predominantly mediated by Y2 receptors, which, together

Abstract PURPOSE: Low-grade fibromyxoid sarcoma (LGFMS) is typically characterized by the specific translocation t(7;16)(q33;p11) and the corresponding fusion gene FUS-CREB3L2. The present study aimed to extract LGFMS-specific, and putatively FUS-CREB3L2-dependent, gene expression patterns to learn more about the pathogenesis of this tumor. EXPERIMENTAL DESIGN: We carried out single nucleotide po

Diagnosis by screening mammography is considered an independent positive prognostic factor, although the data are not fully in agreement. The aim of the study was to explore whether the mode of detection (screening-detected versus symptomatic) adds prognostic information to the St Gallen molecular subtypes of primary breast cancer, in terms of 10-year cumulative breast cancer mortality (BCM).

The ARTeMeD project aims to solve problems of interactivity and real-time in teleradiology. It integrates personal multimedia facilities and patient data access in a common platform that allows radiologists to collaborate from remote sites through a suitable communication support. ARTeMeD is based on asynchronous transfer mode (ATM) network technology and an optimized manipulation of medical image

The effects of nicotine administration (2 mg eight-times daily as nicotine chewing gum for two weeks) on plasma lipid and lipoprotein concentrations were studied in young healthy volunteers. Plasma levels of the nicotine metabolite, cotinine, reached levels comparable to those seen in smokers. Plasma concentrations of triglyceride, cholesterol, HDL cholesterol, LDL cholesterol, and apolipoproteins

Objective: To investigate the association between patient characteristics and disease-specific and generic quality of life (QOL) as well as the degree of bother in women seeking treatment for urinary incontinence (UI). Methods: The Prospective Urinary Incontinence Research (PURE) was a 6-mo observational study with 1055 physicians from 15 European countries enrolling 9487 women. QOL was assessed a

Popular Abstract in Swedish Vattenkraft är Islands främsta energikälla. År 2005 svarade vattenkraft för 80,8% av all elproduktion på Island (7015 Gwh). Vattenkraft påverkas av både variationer och förändringar i vattenflöden. Denna avhandling fokuserar på studier av trender och variationer i tidsserier av vattenflöden och klimatvariabler, kombinerat med modellering av avrinningsområden och analys Hydropower is the main source of electricity production in Iceland. In 2005, 80.8% of all electricity was generated by hydropower (7015 GWh). Hydropower production is affected both by variations and changes in discharge. This thesis focuses on studies of the trends and the variability found in records of discharge and climatic variables, combined with watershed modelling and an analysis of a proje

Essä om bilden av andra världskriget under 1990-talet

This article reconstructs a Hebrew version of the Gloria in Luke 1: 14 with its focus on the righteous remnant of Israel and then analyses the early versions in Greek, Latin, Syriac and Coptic. Finally it gives some later interpretations of the canticle in literature, art and music.

This article discusses why films have not been used more than they have as historical sources and argues that films ought to be used more by historians. Principally, historians can use film in three basic ways, all of which give access to information about the period when it was produced. First, films can with caution be used for information about the persons, objects and events depicted in docum

Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.The present report presents an experimental study of leaching of concrete caused by water percolating through the concrete, or by diffusion from concrete to external water in contact. An apparatus was designed and constructed in which de-ionised water could be forced, by external pressure, through a number of concrete specimens of differing characteristics. It was found that, whereas the initial w

The observation potential of the decays B0s,d → J/ψη with the ATLAS detector at the LHC is described in this paper. At present there exist only upper limits for the branching fractions, but at LHC, a clear signal for the decay mode B0s,d → J/ψη is expected. The branching fraction of this decay mode can thus be measured, and other parameters such as B0s lifetime can be measured as well. The decay m