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Arctic sea ice loss warmed the temperate East Asian winter in the mid-Holocene

The recent colder winters in midlatitude Eurasia have been proposed to result from Arctic sea-ice decline. However, large uncertainties remain regarding this link in the present variable climate. Here, we present ice-rafted debris records from the eastern Arctic and geochemical data from the temperate East China Sea to reconstruct Holocene changes in sea ice and the East Asian winter monsoon. Our

Intersectional socioeconomic disparities in continuous smoking through pregnancy among pre-pregnant smokers in Sweden between 2006 and 2016

Background: While well-established associations exist between socioeconomic conditions and smoking during pregnancy (SDP), less is known about social disparities in the risk of continuous SDP. Intersectional analyses that consider multiple social factors simultaneously can offer valuable insight for planning smoking cessation interventions. Methods: We include all 146,222 pregnancies in Sweden bet

Efficacy of an internet-delivered cognitive enhancement intervention for subjective residual cognitive deficits in remitted major depressive disorder : A randomized crossover trial

Background: Cognitive deficits such as difficulties with attention, memory, and executive functions are frequently reported during remission from depression and relates to adverse functioning in daily life and risk of relapse. There is therefore a need for interventions targeting cognitive deficits after depression. However, few randomized controlled trials have investigated the efficacy of interv

Learning an interpretable end-to-end network for real-time acoustic beamforming

Recently, many forms of audio industrial applications, such as sound monitoring and source localization, have begun exploiting smart multi-modal devices equipped with a microphone array. Regrettably, model-based methods are often difficult to employ for such devices due to their high computational complexity, as well as the difficulty of appropriately selecting the user-determined parameters. As a

The natural menstrual cycle revisited – can natural cycle be trusted

Background: The serum progesterone (P4) level during the luteal phase (LP) plays a crucial role in the initiation and maintenance of pregnancy. However, it is unclear whether the natural cycle consistently provides the best endocrine profile and whether mid-luteal serum P4 levels are always sufficient to support implantation and early pregnancy. The question has become more relevant in relation to

Children’s voices on their values and moral dilemmas when being cared and treated for cancer– a qualitative interview study

Background: Childhood cancers affect about 350 children every year in Sweden and are life-threatening diseases. During the treatment period, situations arise that can become morally challenging for the child. When knowing children’s values and morally challenging situations in childhood cancer care, targeted ethics support could be developed and used in care. Aim: To explore children’s values and

Workplace Incivility in Caregiving : Relations to Work Motivation and Psychological Need Satisfaction

Workplace incivility is a pervasive issue with implications for employee well-being. Drawing upon Self-Determination Theory, this study explores the association between experienced workplace incivility, need satisfaction, and work motivation and investigates whether workplace incivility is negatively associated with autonomous work motivation. We hypothesize that experiencing workplace incivility

Effect of Short-Term Lactic Fermentation on Polyphenol Profile and Antioxidant Capacity in White and Red Quinoa Varieties

Quinoa (Chenopodium quinoa Willd.) is a pseudocereal originally grown in the Andean region of South America. This study focused on investigating the changes in phenolic profile and antioxidant capacity in white and red quinoa varieties after short-term fermentation with Lactiplantibacillus plantarum 299v®. During fermentation, pH and lactic acid formation were monitored every three hours until pH

Controlling Majorana hybridization in magnetic chain-superconductor systems

We propose controlling the hybridization between Majorana zero modes at the ends of magnetic adatom chains on superconductors by an additional magnetic adatom deposited close by. By tuning the additional adatom's magnetization, position, and coupling to the superconductor, we can couple and decouple the Majorana modes, as well as control the ground-state parity. The scheme is independent of micros

Modulation of ERP responses by predictability of information in negated contexts

Modulation of ERP responses by predictability of information in negated contextsPrevious research has shown that language comprehension is incremental and that we can keep up with language input because we make predictions about the upcoming information [1]. If these predictions are confirmed, processing is facilitated. In event-related potential (ERP) studies, this facilitation effect appears in

LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation

In mammals, the leucine-rich pentatricopeptide repeat protein (LRPPRC) and the stem-loop interacting RNA-binding protein (SLIRP) form a complex in the mitochondrial matrix that is required throughout the life cycle of most mitochondrial mRNAs. Although pathogenic mutations in the LRPPRC and SLIRP genes cause devastating human mitochondrial diseases, the in vivo function of the corresponding protei