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Management Control of a Meal Experience: comments on the Five Aspects Meal Model

The Five Aspects Meal Model (FAMM) is a structured approach towards explaining what makes up an entire meal experience. One aspect in particular, the management control system, has a clear potential of being developed to increase the practical impact of the model. Scholars suggest that the management control system aspect works backstage, where matters of computer work, handling statistics, market

Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner

Objectives: To investigate the bactericidal activity of antiviral and anticancer nucleoside analogues against a variety of pathogenic bacteria and characterize the activating enzymes, deoxyribonucleoside kinases (dNKs). Methods: Several FDA-approved nucleoside analogue drugs were screened for their potential bactericidal activity against several clinical bacterial isolates and type strains. We ide

Phosphatidylinositol 4-Kinase Associated with Spinach Plasma Membranes. Isolation and Characterization of Two Distinct Forms

Highly purified plasma membranes from spinach (Spinacia oleracea L.) leaves contained phosphatidylinositol (PtdIns) kinase activity that was firmly associated with the membrane. The enzyme was solubilized by detergent treatment (2% [w/v] Triton X-100) and purified by heparin-Sepharose and Q-Sepharose chromatography. Two enzymically active fractions, QI and QII, both exhibiting PtdIns 4-kinase acti

Pragmatic comparison of beta(2)-agonist side effects within the worldwide atosiban versus beta agonists study

Objective: While beta(2)-agonists for the acute treatment of preterm labour unequivocally reduce the odds of delivery within 48 hand 7 days, they have been associated with substantial maternal and fetal side effects. We aimed to compare side effect profiles of beta(2)-agonist tocolytics. Study design: Pragmatic comparison of ritodrine, salbutamol and terbutaline from re-analysis of data obtained w

Impact of delirium on professionals

There is a paucity of empirical research on the impact of delirium on professionals' reactions, interpretations or attitudes to people in a delirious state. This is striking because it stands to reason that it is demanding to take care of a person who is disoriented, perhaps agitated and who may hallucinate and/or act in a manner that calls for interventions involving the use of force or actions t

The Explanatory Role of Factor Portfolios for Industries Exposed to Foreign Competition

Our purpose is to find factors that are important for expected returns and risk of Swedish industrial portfolios during 1980–1997. The tested factors are supposed to be essential for a small open economy. We take into account the small sample problem that surfaces in the form of firms dominating the value weighted test portfolios. An extreme bound analysis (EBA) investigates the robustness of the

Characterization of recombinant amino-terminal NC4 domain of human collagen IX - Interaction with glycosaminoglycans and cartilage oligomeric matrix protein

The N-terminal NC4 domain of collagen IX is a globular structure projecting away from the surface of the cartilage collagen fibril. Several interactions have been suggested for this domain, reflecting its location and its characteristic high isoelectric point. In an attempt to characterize the NC4 domain in more detail, we set up a prokaryotic expression system to produce the domain. The purified

Mass measurements along the rp-process path

The path and termination point for the rp-process above Ni-56 is uncertain due to a tack of knowledge of nuclear properties, especially masses, near the proton drip line. To address this need we have begun a program to measure masses of nuclei along the rp-process pathway in the A similar to 60-80 region using beta-gamma coincidence spectroscopy. Results for Se-71 are presented and a preliminary e

Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture

The capture of human acute mycloid leukemia KG-1 cells expressing the CD34 surface antigen and the fractionation of human blood lymphocytes were evaluated on polyvinyl alcohol (PVA)-cryogel beads and dimethyl acrylamide (DMAAm) monolithic cryogel with immobilized protein A. The affinity ligand (protein A) was chemically coupled to the reactive PVA-cryogel beads and epoxy-derivatized monolithic cry

The safety of antidepressant drugs during pregnancy

This article discusses known or suspected effects of maternal use of antidepressants during pregnancy on pregnancy outcome. It is unlikely that any marked teratogenic effect occurs with the possible exception of an increased risk for cardiovascular defects after maternal use of clomipramine or paroxetine. An increased risk for preterm birth is seen. Transient neonatal symptoms are common after the

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

ATP-dependent priming of the secretory granules precedes Ca(2+)-regulated neuroendocrine secretion, but the exact nature of this reaction is not fully established in all secretory cell types. We have further investigated this reaction in the insulin-secreting pancreatic B-cell and demonstrate that granular acidification driven by a V-type H(+)-ATPase in the granular membrane is a decisive step in

Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions

It is becoming increasingly evident that single-locus effects cannot explain complex multifactorial human diseases like cancer. We applied the multi-factor dimensionality reduction (MDR) method to a large cohort study on gene-environment and gene-gene interactions. The study (case-control nested in the EPIC cohort) was established to investigate molecular changes and genetic susceptibility in rela

Ghrelin and insulin gene expression changes in streptozotocin-induced diabetic rats after rosiglitazone pretreatment

The aim of the study was to evaluate the effect of rosiglitazone treatment on islet ghrelin and insulin gene expressions in streptozotocin (STZ)-induced diabetic rats. Animals were divided into four groups. 1. Intact controls. 2. Rosiglitazone-treated controls. 3. STZ-induced diabetes. 4. Rosiglitazone-treated diabetes, Rosiglitazone was given for 7 days at a dose of 20 mg/kg body weight. Ghrelin

Micro-organization of olivocerebellar and corticonuclear connections of the paravermal cerebellum in the cat

The olivocerebellar and corticonuclear connections of the forelimb area of the paravermal medial C3 zone were studied in the cat using a combined electrophysiological and fluorescent tracer technique. During an initial operation under barbiturate anaesthesia, lobules IV/V of the cerebellar anterior lobe were exposed and small injections of dextran amines tagged with rhodamine or fluorescein were m

The response of heterotrophic CO2-flux to soil warming

In a forest ecosystem at steady state, net carbon (C) assimilation by plants and C loss through soil and litter decomposition by heterotrophic organisms are balanced. However, a perturbation to the system, such as increased mean soil temperature, will lead to faster decay, enhancing CO2 release from decomposers, and thus upsetting the balance. Recent in situ experiments have indicated that the sti

Assesing nutrient sustainability of forest production for different tree species considering Ca, Mg, K, N and P at Bjornstorp Estate, Sweden

An assessment of nutrient sustainability has been done for stands of European beech, Sycamore maple, European oak, Norway spruce, Larch, Grandis fir and Douglas fir at Bjornstorp Estate in southern Sweden. To estimate the nutrient sustainability, mass balance was calculated with respect to Ca, Mg, K, N and P. The release from mineral weathering was calculated using the PROFILE model. The leaching

Nocturnal bees learn landmark colours in starlight.

Honeybees, like humans and most other vertebrates, are colour-blind in dim light. Bees are primarily day-active and have apposition compound eyes, the typical eye design of diurnal insects. Most bees are trichromats with photoreceptors sensitive in the UV, blue and green [1]. While their diurnal colour vision was established almost 100 years ago, honeybees are known to be colour-blind in moonlight

Selenium and cancer: biomarkers of selenium status and molecular action of selenium supplements

Background The relationship between selenium and cancer involves many different aspects. These include the forms of selenium present in the diet and in the body, their functions and mechanisms of action, and methods employed in assessing an individual's selenium nutritional status-both in general, and in epidemiological studies of the risk of cancer in relation to diet, as well as in connection wi

In vivo measurement of parameters of dosimetric importance during interstitial photodynamic therapy of thick skin tumors

A system for interstitial photodynamic therapy is used in the treatment of thick skin tumors. The system allows simultaneous measurements of light fluence rate, sensitizer fluorescence, and tissue oxygen saturation by using the same fibers as for therapeutic light delivery. Results from ten tumor treatments using delta-aminolevulinic acid (ALA)-induced protoporphyrin IX show a significant, treatme

Metastability of Multi-Lamellar Vesicles in a Nonionic System

Nuclear magnetic resonance spectroscopy and rheological analysis have been used to investigate the stability of mechanically induced tri-ethylene-glycol-mono-n-decyl-ether (C10E3)/deuterium oxide (D2O) multi-lamellar vesicles (MLVs) and the transition from MLVs to planar lamellae. It was found that MLVs prepared by vortex stirring, relax back to the lamellar phase in a few hours while the relaxati