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Background: We used a computational method to quantitatively investigate the relationship between personality and written narratives of life events. Agentic (i.e., self- directedness), communal (i.e., cooperativeness), and spiritual (self-transcendence) traits were of special interest because they represent individual differences in intentional val- ues and goals, in contrast to temperament traits

Physical activity is beneficial for the health of persons with disabilities but the levels of such activity are lower than for persons without disability. In addition the level of physical activity decreases with increasing age. For persons aging with a disability it may be a challenge to engage in physical activity, partly because of the disability and partly because of contextual barriers. One g

Conventional motion and eddy-current correction, where each diffusion-weighted volume is registered to a non diffusion-weighted reference, suffers from poor accuracy for high b-value data. An alternative approach is to extrapolate reference volumes from low b-value data. We aim to compare the performance of conventional and extrapolation-based correction of diffusional kurtosis imaging (DKI) data,

In a population-based study on cobalamin status and incident fractures in elderly men (n = 790) with an average follow-up of 5.9 years, we found that low levels of metabolically active and total cobalamins predict incident fractures, independently of body mass index (BMI), bone mineral density (BMD), plasma total homocysteine (tHcy), and cystatin C. Cobalamin deficiency in elderlies may affect bon

A bulk of experimental evidence supports the idea that the stroke-damaged adult brain makes an attempt to repair itself by producing new neurons also in areas where neurogenesis does not normally occur (e.g., the striatum and cerebral cortex). Knowledge about mechanisms regulating the different steps of neurogenesis after stroke is rapidly increasing but still incomplete. The functional consequenc

Renal transplant outcomes exhibit large inter-individual variability, possibly on account of genetic variation in immune-response mediators and genes influencing the pharmacodynamics/pharmacokinetics of immunosuppressants. We examined 21 polymorphisms from 10 genes in 237 de novo renal transplant recipients participating in an open-label, multicenter study [Cyclosporine Avoidance Eliminates Seriou

In this work we have calculated U from first principles for the early lanthanides (Ce-Gd) using the constrained random phase approximation (cRPA). We compare the static limit of U with experimental estimations from x-ray photoemission spectroscopy (XPS) and bremsstrahlung isochromat spectroscopy (BIS) spectra and also discuss the frequency dependence of U across the series. The localized subspace

In this article we propose a modification of the recently introduced divergence information criterion (DIC, Mattheou et al., 2009) for the determination of the order of an autoregressive process and show that it is an asymptotically unbiased estimator of the expected overall discrepancy, a nonnegative quantity that measures the distance between the true unknown model and a fitted approximating mod

Late Weichselian and early Holocene climatic and environmental changes are inferred from stable carbon and oxygen isotope records obtained on bulk and biogenic carbonates from the sediment sequence of Lake Lednica, western Poland. Along with sediment and pollen stratigraphic data, a wide range of carbonate components occurring in the sediments was analysed for delta C-13 and delta O-18, including

This presentation is a summary and a discussion of the ICRU Reports Nos 29, 50, 62 and 71.

Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. The high risk of hypoxia and fetal death has to be balanced against that of extreme preterm birth with associated morbidity. The clinical

Interstitial fluid flow and associated shear stress are relevant mechanical signals in cartilage and bone (patho)physiology. However, their effects on chondrosarcoma cell motility, invasion and metastasis have yet to be delineated. Using human SW1353, HS.819.T and CH2879 chondrosarcoma cell lines as model systems, we found that fluid shear stress induces the accumulation of cyclic AMP (cAMP) and i