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Foods elaborated with vegetable by-product effects on blood lipid levels : A systematic review

Vegetable by-products, produced in large quantities worldwide, contain significant amounts of bioactive compounds and fiber, which have been shown to offer health benefits, such as regulating blood lipid levels. Dyslipidemia, a primary target in the clinical metabolic control of susceptible populations, is strongly influenced by diet. Hence, this systematic review aims to present the main findings

The Use of Crowd Models for Risk Analysis During the Covid-19 Pandemic

The emergence of pandemics like Covid-19 has raised important issues regarding the safe utilisation of spaces due to the potential for virus transmission in both enclosed and open built environments. This chapter explores the challenges posed by pandemics in terms of safe space utilisation, considering the potential virus transmission risks. It presents a risk analysis methodology that makes use o

Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022 : a study using nationwide population data

While there is substantial evidence on excess mortality in the first two years of the COVID-19 pandemic, no study has conducted a cause-specific analysis of excess mortality for the whole period 2020–2022 across multiple countries. We examined cause-specific excess mortality during 2020–2022 in Denmark, Finland, Norway, and Sweden—four countries with similar demographics and welfare provisions, wh

LES of Biomass Syngas Combustion in a Swirl Stabilised Burner : Model Validation and Predictions

In this work, numerical investigations were performed using large eddy simulations and validated against detailed measurements in the CeCOST swirl stabilised burner. Both cold and reactive flow have been studied and the model has shown a good agreement with experiments. The verification of the model was done using the LES index of quality and a single grid estimator. The cold flow simulations pred

Farm-level acceptability of contract attributes in agri-environment-climate measures for biodiversity conservation

Farmers are key to preserving and restoring semi-natural pastures (SNPs) while maintaining their environmental and cultural significance. To support these efforts, it is essential to create favorable conditions that encourages voluntary participation of farmers in agri-environment-climate measures (AECM) for SNP management. This study aims to assess acceptability of contract attributes within AECM

Oat polar lipids and sunflower lecithin similarly improve cardiometabolic risk markers and appetite controlling hormone responses after breakfast and a subsequent lunch. A randomized crossover study in healthy adults

Introduction: The alarming global increase in lifestyle-related disorders such as obesity and type 2 diabetes mellitus (T2DM) has increased during the last several decades. Poor dietary choices significantly contribute to this increase and prevention measures are urgently needed. Dietary intake of bioactive compounds found in foods are linked to a decrease likelihood of these disorders. For t

Genome plasticity shapes the ecology and evolution of Phocaeicola dorei and Phocaeicola vulgatus

Phocaeicola dorei and Phocaeicola vulgatus are very common and abundant members of the human gut microbiome and play an important role in the infant gut microbiome. These species are closely related and often confused for one another; yet, their genome comparison, interspecific diversity, and evolutionary relationships have not been studied in detail so far. Here, we perform phylogenetic analys

Intercultural Translation and Application of the German Version of King's Parkinson's Disease Pain Questionnaire in Fluctuating Parkinson's Disease

Background. Pain is common in Parkinson's disease (PD) and impairs quality of life. The King's PD pain questionnaire (KPPQ) is a standardized, reliable, and valid self-administered questionnaire for screening of pain in PD. We developed a linguistically validated German version of the KPPQ and applied it to a cohort with fluctuating PD. Methods. The interculturally adapted German translation was p

Population-based risk factors and urogenital comorbidities associated with genital herpes : A nationwide study of 4 million women

Objectives: To explore the population-based risk factors for genital herpes in women and examine whether genital herpes occurs at higher rates in women diagnosed with cervical neoplasia and common urogenital infections. Methods: An open cohort study consisting of 4,097,075 women ≥15 years of age in Sweden (2002-2018). The outcome was genital herpes diagnosis. The predictor variables were sociodemo

Airy Flight

opus: Op. 91bsubtitle: Bossainstrumentation: trumpet, brass quintetdedicated to: Håkan Hardenbergercommissioner: gift for Håkan's 50th birthday from the composer

Improved snow depth retrieval over Arctic sea ice from FY-3 satellites using machine learning and its future scenario projection

Snowpack atop sea ice plays a vital role in the Arctic heat and energy balance by reducing the energy transfer between the atmosphere and the ocean. This study presents an improved snow depth retrieval model over Arctic multiyear ice (MYI) from the Microwave Radiometer Imager (MWRI) data of the Fengyun-3 (FY-3) series satellites using the optimal machine learning approach identified. Validation ag

The pace of life for forest trees

Tree growth and longevity trade-offs fundamentally shape the terrestrial carbon balance. Yet, we lack a unified understanding of how such trade-offs vary across the world's forests. By mapping life history traits for a wide range of species across the Americas, we reveal considerable variation in life expectancies from 10 centimeters in diameter (ranging from 1.3 to 3195 years) and show that the p

The experience and implications of pain in systemic lupus erythematosus : A qualitative interview study focusing on the patient’s perspective

Background: Pain is one of the most frequently reported symptoms and often one of the first subjective symptoms in patients with systemic lupus erythematosus (SLE). A previous study indicated that most patients with SLE reported low levels of SLE-related pain. However, a subgroup of patients reported high levels of pain ≥40 mm (0-100 mm) and had a substantial symptom burden in terms of fatigue, an

Constraints on the availability of marginal land for bioenergy production in southern Sweden

roduction of biomass for bioenergy on marginal land has been promoted to decrease the use of non-renewable energy without competing with food production. Previous estimates of marginal land and abandoned farmland in Sweden available for bioenergy production are based on general statistics and assumptions but lack in-depth analyses of potential alternative land-use values. Easily accessible public

Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease

Alexander disease (AxD) is a rare and severe neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP). While the exact disease mechanism remains unknown, previous studies suggest that mutant GFAP influences many cellular processes, including cytoskeleton stability, mechanosensing, metabolism, and proteasome function. While most studies have primarily focused on GFAP

“We had to become everything” : employee innovation due to COVID-19 in the Italian public healthcare system

Purpose: COVID-19 has profoundly shaped human interactions, and, within public healthcare systems, care relations. Through the lens of social suffering, this study explores how employee innovation is shaped by the pandemic crisis and different managerial approaches in the context of public geriatric care in Northeast Italy. Design/methodology/approach: This study adopts a qualitative methodology.

Bioreactor for the selection of microalgae

The invention relates to a bioreactor comprising a tank (100) capable of being operated for a working period, said tank (100) being intended to receive a culture medium comprising a cellular culture of photosynthetic microorganisms, a light source (200) arranged to emit incident light having a chosen incoming light intensity (Iin) in the direction of the tank, a temperature probe (400) for measuri

Randomized Trial of Cholesterol Lowering With Evolocumab for Cardiac Allograft Vasculopathy in Heart Transplant Recipients

Background: Cardiac allograft vasculopathy is characterized by increased coronary intimal thickness and is a leading cause of death in heart transplant (HTx) recipients despite the routine use of statins. The experience with inhibitors of proprotein convertase subtilisin-kexin type 9 in HTx recipients is limited. Our hypothesis was that lowering cholesterol with the proprotein convertase subtilisi

Real-time structural characterization of protein response to a caged compound by fast detector readout and high-brilliance synchrotron radiation

Protein dynamics are essential to biological function, and methods to determine such structural rearrangements constitute a frontier in structural biology. Synchrotron radiation can track real-time protein dynamics, but accessibility to dedicated high-flux single X-ray pulse time-resolved beamlines is scarce and protein targets amendable to such characterization are limited. These limitations can

Effect of arthroscopic partial meniscectomy on structural degeneration of the knee – A 5-year MRI-based follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial

Objective: To assess the 5-year effects of arthroscopic partial meniscectomy (APM) vs. placebo surgery on the development of the structural changes of the knee by magnetic resonance imaging (MRI). Design: This multicentre, randomized, participant- and outcome-assessor-blinded, placebo-surgery-controlled trial was carried out in Finland. We randomized 146 adults, mean age 52 years (range 35 to 65)