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Introducing Usability Testing in the Risk Management Process in Software Development

Human beings make errors and that is nothing that we can avoid completely. We can however lower the risk of people doing wrong in situations where, for example, medical devices are used. The overall objective of the research presented in this paper is to investigate how usability testing can contribute to software risk management process in the medical device domain. Experience has been collected

The organization of honeybee ocelli: Regional specializations and rhabdom arrangements

We have re-investigated the organization of ocelli in honeybee workers and drones. Ocellar lenses are divided into a dorsal and a ventral part by a cusp-shaped indentation. The retina is also divided, with a ventral retina looking skywards and a dorsal retina looking at the horizon. The focal plane of lenses lies behind the retina in lateral ocelli, but within the dorsal retina in the median ocell

Some comments on the substituted judgement standard.

On a traditional interpretation of the substituted judgement standard (SJS) a person who makes treatment decisions on behalf of a non-competent patient (e.g. concerning euthanasia) ought to decide as the patient would have decided had she been competent. I propose an alternative interpretation of SJS in which the surrogate is required to infer what the patient actually thought about these end-of-l

Juridifiering som institutionell förändring. Om mötet mellan straffrätt och socialrätt vid interorganisatorisk samverkan

Denna artikel handlar om vad som sker i mötet mellan straffrätt och socialrätt vid interorganisatorisk samverkan i en kontext av barnahus - där socialtjänst, hälso- och sjukvård samt polis- och åklagarmyndigheter samverkar under ett gemensamt tak kring utredningar av misstänkta brott mot barn. Utifrån ett rättssociologiskt institutionellt perspektiv presenteras och vidareutvecklas förståelsen för

Pre-treatments for enhanced biochemical methane potential of bamboo waste

Various pre-treatments (acid, alkaline, enzyme and alkaline aided enzyme also termed combined) were evaluated on different fractions of bamboo waste from a chopstick production factory. Chemical oxygen demand (COD) solubilisation, monomeric/dimeric sugar yield, methane yield enhancement and methane production rate were assessed. The biochemical methane potential was determined in batch assays unde

Large-scale pollination experiment demonstrates the importance of insect pollination in winter oilseed rape.

Insect pollination, despite its potential to contribute substantially to crop production, is not an integrated part of agronomic planning. A major reason for this are knowledge gaps in the contribution of pollinators to yield, which partly result from difficulties in determining area-based estimates of yield effects from insect pollination under field conditions. We have experimentally manipulated

Neuropeptide Y Y1 Receptor Hippocampal Overexpression Via Viral Vectors Is Associated With Modest Anxiolytic-Like and Proconvulsant Effects in Mice

Neuropeptide Y (NPY) exerts anxiolytic-and antidepressant-like effects in rodents that appear to be mediated via Y1 receptors. Gene therapy using recombinant viral vectors to induce overexpression of NPY in the hippocampus or amygdala has previously been shown to confer anxiolytic-like effect in rodents. The present study explored an alternative and more specific approach: overexpression of Y1 rec

Photophysics of indole-2-carboxylic acid in an aqueous environment studied by fluorescence spectroscopy in combination with ab initio calculations.

The photo-physics and -chemistry of indoles are known to be highly complex and strongly dependent on their precise molecular structure and environment. Combination of spectroscopic analysis with quantum chemical calculations should be a powerful tool to unravel precise excited state deactivation mechanisms. At the same time, combined studies are seldom and likely far from trivial. In this work we

Use and misuse of PLFA measurements in soils

The determination of the phospholipid fatty acid (PLFA) pattern of soil organisms has become one of the most commonly used methods to study microbial community structure. Here we recapitulate the background of our work applying the PLFA method to soil in the early 1990s. We also stress that although the PLFA method was, and still is, a rapid and sensitive method to detect changes in the microbial

Freeze-out radii extracted from three-pion cumulants in pp, p-Pb and Pb-Pb collisions at the LHC

In high-energy collisions, the spatio-temporal size of the particle production region can be measured using the Bose-Einstein correlations of identical bosons at low relative momentum. The source radii are typically extracted using two-pion correlations, and characterize the system at the last stage of interaction, called kinetic freeze-out. In low-multiplicity collisions, unlike in high-multiplic

A Purkinje cell Timing Mechanism. On the Physical Basis of a Temporal Duration Memory.

The standard view of neural signaling is that a neuron can influence its target cell by exciting or inhibiting it. Learning is thought to involve strengthening or weakening synaptic connections. For most behaviors, the brain must learn to produce precisely timed activity patterns. Learned response timing is indispensable for a wide range of tasks and requires learning of interstimulus intervals (I

Individual Placement and Support (IPS) for persons with severe mental illness -Outcomes of a randomised controlled trial in Sweden

Popular Abstract in Swedish Den arbetsrehabilitering som traditionellt erbjuds personer med psykisk funktionsnedsättning kan beskrivas som en trappa där varje steg består av olika åtgärder för att öka personernas arbetsförmåga. Målet är att personerna successivt skall bli friskare, öka sin funktionsnivå och utveckla fler färdigheter innan de kan ta steget ut till ett konkurrensutsatt arbete. För pIn the light of the limited research on the subject of Individual Placement and Support (IPS) in a Swedish context, this thesis has contributed with knowledge of the effectiveness and experiences of IPS among persons with severe mental illness (SMI) living in Sweden. The thesis has also provided information about the work motivation among those persons with SMI who seek vocational support by IPS.

Functional Magnetic Resonance Imaging in Prostate Cancer

Context: Magnetic resonance imaging (MRI) combined with magnetic resonance spectroscopy imaging (MRSI), dynamic contrast-enhanced MRI, and diffusion-weighted MRI emerged as promising tests in the diagnosis of prostate cancer, and they show encouraging results. Objective: This review emphasizes different functional MRI techniques in the diagnosis of prostate cancer and includes information about th

Clinical Implications of Electrocardiographic Left Ventricular Strain and Hypertrophy in Asymptomatic Patients With Aortic Stenosis The Simvastatin and Ezetimibe in Aortic Stenosis Study

Background-The prognostic impact of ECG left ventricular strain and left ventricular hypertrophy (LVH) in asymptomatic aortic stenosis is not well described. Methods and Results-Data were obtained in asymptomatic patients randomized to simvastatin/ezetimibe combination versus placebo in the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study. Primary end point was the first of myocardial inf

Good or bad ethanol – what determines this?

The purpose of this study is to describe how the energy efficiency and greenhouse gas (GHG) benefits of ethanol depend on local conditions and calculation methods. The following four parameters have been identified as crucial to the GHG benefits of ethanol: (i) energy efficiency and emissions of nitrous oxide during cultivation, (ii) what kind of fuel is used in ethanol plants, (iii) how efficient

A toxicological and dermatological assessment of aryl alkyl alcohol simple acid ester derivatives when used as fragrance ingredients

The aryl alkyl alcohol simple acid ester derivatives (AAASAE) group of fragrance ingredients was critically evaluated for safety following a complete literature search of the pertinent data. For high end users, calculated maximum skin exposures vary widely from 0.01% to 4.17%. AAASAE exhibit a common route of primary metabolism by carboxylesterases resulting in the formation of the simple acid and

Influence of Flow Swirling on the Aerothermodynamic Behaviour of Flames

The present work focuses on the numerical simulation of diffusive flames in a confined high-swirl burner. Navier-Stokes equations expressed for a time-dependent, compressible, and three-dimensional flow with finite-rate kinetics are solved for lean methane/air mixtures. A simplified mechanism is used to model the combustion. Non-reactive and reactive cases are contrasted for a swirl number of 0.95