Chiral amines are important building blocks in the pharmaceutical industry, and the biocatalytic synthesis of these compounds using ω-transaminases has been increasingly studied in recent years. In principal, asymmetric synthesis of chiral amines from a prochiral ketone is the preferable route, but it is often hampered by an unfavourable equilibrium position and product inhibition. An effective me

Optimal data detection of data transmitted over a linear channel can always be implemented through the Viterbi algorithm (VA). However, in many cases of interest the memory of the channel prohibits direct application of the VA. A popular and conceptually simple method in this case, studied since the early 1970s, is to first filter the received signal in order to shorten the memory of the channel,

A quick guide to the Australian Bogong moth, the nocturnal counterpart of the migratory Monarch butterfly.

In general, diffusion rates in extractions are enhanced by increasing the temperature. In this study, we instead add compressed liquid carbon dioxide to the extraction phase to accomplish faster mass transfer. The feasibility of using carbon dioxide expanded ethanol (CXE) as the extraction phase was explored, targeting two medium-polar analytes, α-pinene and cis-verbenol in Boswellia sacra tree re

Platelets have been reported to become activated in response to bacteria and this is proposed to contribute to the acute response to bacterial infection. In the present study, we investigated platelet aggregation in response to group G streptococci (GGS) in vitro in healthy human donors and in vivo in a mouse model of streptococcal sepsis. Platelet aggregation by GGS was dependent on the bacterial

Blogs, social media, and search engines have democratized information seekers and providers. However, the same affordances of the Internet have also contributed to resurgence and transformation of far-right and racist communities. Despite a growing number of studies of far-right communities, little attention has so far been paid to the mechanisms through which far-right and racist ideologies are p

Nervous tissue is one of the most metabolically expensive animal tissues, thus evolutionary investments that result in enlarged brain regions should also result in improved behavioural performance. Indeed, large-scale comparative studies in vertebrates and invertebrates have successfully linked differences in brain anatomy to differences in ecology and behaviour, but their precision can be limited

Cloud computing has dramatically simplified the deployment of new software and, indeed, the number of applications that are hosted by cloud providers every day is increasing. The data center owner should provide computing capacity to a set of customers, each of them powering up and down virtual machines dynamically, to handle variations in the incoming requests. Cloud providers, however, should al

This talk discusses our old work on the hadronic light-by-light contribution to the muon anomalous magnetic moment and some more recent contributions. I discuss the various contributions starting with pseudoscalar meson exchange, the quark-and pion-loop, as well as scalar and a1-exchange. For the π0-exchange I point out a possible large enhancement when only connected contributions are included. F

Evolutionary economic geographers propose that regional diversification is a path-dependent process whereby industries grow out of pre-existing industrial structures through technologically related localised knowledge spillovers and learning. This article examines whether this also applies to emerging radical technologies that create the foundation for new industries. The article develops a new me

Many homes in affluent Western societies have an ongoing battle against domestic mess, because of the steady inflow of new acquisitions. This essay looks at the ways in which mess has travelled through modern history and has ended up as both a powerful metaphor and a constant everyday worry in consumer life. In this process, mess has often been defined as a problematic condition, often reflecting

Literature on socio-technical transitions has primarily emphasized the co-determination of institutions and technologies. In this paper, we want to focus on how actors play a mediating role between these two pillars of a socio-technical system. By introducing the theoretical concept of institutional work, we contribute to the conceptualization and empirical assessment of agency processes in socio-

Urban water sectors in industrialised countries are increasingly facing a diverse range of challenges. Aging assets, environmental concerns and economic issues put pressure on the current governance and organisation of these sectors. In recent years, a plethora of neoliberal reforms have been initiated in various countries as efforts to counteract these developments. While rather successful in inf

Abstract: Systems for studying the toxicity of metal aggregates on the airways are normally not suited for evaluating the effects of individual particle characteristics. This study validates a set-up for toxicological studies of metal aggregates using an air–liquid interface approach. The set-up used a spark discharge generator capable of generating aerosol metal aggregate particles and sintered n

Introduction: The aim was to evaluate surgical treatment of newly diagnosed uterine cancer in a Swedish population. Material and methods: Data in the GynOp registry from 2008 to 2014 were analyzed. Results: In total, 3443 cases were included: 430 (12%) were robotic-assisted laparoscopic, 272 (8%) laparoscopic, and 2741 (80%) abdominal operations. There was an increasing trend in minimally invasive

Many innovation studies focus on innovation as an outcome measured by patents or innovation statistics and tend to neglect the notion that innovation processes are contingent and unfold over time. This simplistic view of innovation reduces the role of geography to a matter of statistical measures of causalities that frequently seems to favour local over international ties. However, this paper exam

Background: Many women of childbearing age are occupationally active, which leads to a large number of pregnancies potentially exposed to occupational exposures. Occupational noise has been identified as a risk factor for hearing impairment in adults. However, very few studies have assessed the effect of occupational noise on the fetus. Objectives: The aim of this study was to investigate whether