Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representa

Uridine residues present at the wobble position of eukaryotic cytosolic tRNAs often carry a 5-carbamoylmethyl (ncm5), 5-methoxycarbonylmethyl (mcm5), or 5-methoxycarbonylhydroxymethyl (mchm5) side-chain. The presence of these side-chains allows proper pairing with cognate codons and they are particularly important in tRNA species where the U34 residue is also modified with a 2-thio (s2) group. The

It is increasingly important to rapidly receive information on the antimicrobial susceptibility of bacteria due to the rise in antimicrobial resistance worldwide. However, traditional phenotypic methods are time-consuming. Thus, the objective of this study was to develop a rapid assay that can detect antibiotic-resistant bacterial isolates phenotypically in less than 2 h. The microplate assay used

Objectives: To evaluate a cancer detecting artificial intelligence (AI) algorithm on serial biopsies in patients with prostate cancer on active surveillance (AS). Patients and methods: A total of 180 patients in the Prostate Cancer Research International Active Surveillance (PRIAS) cohort were prospectively monitored using pre-defined criteria. Diagnostic and re-biopsy slides from 2011 to 2020 (n

Autistic persons often have difficulties with social interaction and communication. Sensory impressions are often processed differently than in neurotypicals. The person may be negatively affected bodily, e.g., being unstable or having reduced body awareness. The body awareness may be observed as an expression in movement quality. However, there is a lack of knowledge about experiences, assessment

The magnetic Laplacian with a step magnetic field has been intensively studied during the last years. We adapt the construction introduced by Bonnaillie-Noël et al. [Bull. London Math. Soc. 56, 2529 (2024)] to prove the existence of bound states of a new effective operator involving a magnetic step field on a domain with an almost flat magnetic barrier. This result emphasizes the fact that even a

Recent work has shown that 8-bit floating point (FP8) can be used for efficiently training neural networks with reduced computational overhead compared to training in FP32/FP16. In this work, we investigate the use of FP8 training in a federated learning context. This brings not only the usual benefits of FP8 which are desirable for on-device training at the edge, but also reduces client-servercom

The ATLAS trigger system is a crucial component of the ATLAS experiment at the LHC. It is responsible for selecting events in line with the ATLAS physics programme. This paper presents an overview of the changes to the trigger and data acquisition system during the second long shutdown of the LHC, and shows the performance of the trigger system and its components in the proton-proton collisions du

Exhibition of video works by iconic American artist, Jack Pierson curated by Alejandro Cesarco at Galería Elba Benítez, Madrid (Spain)/08/ presents three refreshing videos by iconic American artist Jack Pierson, recorded in Hollywood, Florida, in 1997. Like the rest of his work, these three videos are driven by desire and that desire—mediated, just out of reach — is inextricably linked to differen

With the aim to advance the understanding of immune regulation in MCL and to identify targetable T-cell subsets, we set out to combine image analysis and spatial omic technology focused on both early and late differentiation stages of T cells. MCL patient tissue (n = 102) was explored using image analysis and GeoMx spatial omics profiling of 69 proteins and 1812 mRNAs. Tumor cells, T helper (TH) c

This study reviews the literature on TOUCH to establish an analytical framework for the study of TOUCH in communication through language. Two questions are at the heart of the study—an ontological and a methodological one: What counts as TOUCH, and how can we investigate the way we talk about TOUCH? Within the broad framework of cognitive semantics, we offer a general approach to TOUCH and identif

Subtitled / Subtitulado is an open-ended reflection on the figure of the artist and is anchored around two central works: Midcareer, a new video work that addresses the advantages and difficulties of midcareerness, and The Style it Takes (Excerpts), an older (and upended) photographic work, which explores the social function of art and the shifting roles of the artist persona. Style, that which is

Society is highly dependent on services such as electricity, communication, and transportation. Furthermore, the critical infrastructures (CIs) that provide these services are highly interdependent through a number of physical, economic and organizational links. In this context, a holistic perspective on risk is essential to avoid suboptimal interventions and risk-related blind spots. Here, fragme

Photoperiod, the relative duration of daylight in a 24-hour diel-cycle, is an environmental cue that influences physiological processes in birds, regulating life-history events such as reproduction and migration. Here we study whether variations in photoperiod affect migratory behaviors, including activity, orientation, and body mass, across bird species during 2023 spring and autumn migration. Ou

Anolis sagrei exhibit a female limited dorsal pattern polymorphism with two discrete pattern morphs (chevron or diamond). The underlying genetic basis has been traced to a Mendelian autosomal locus (gene CCDC170) which is adjacent to the gene for estrogen receptor one (ESR1). Thus, this model system gives an excellent opportunity to study the origin and maintenance of new phenotypic variants. In t

Background The World Health Organisation (WHO) 2013 diagnostic criteria for gestational diabetes mellitus (GDM) has been criticised due to the limited evidence of benefits on pregnancy outcomes in different populations when switching from previously higher glycemic thresholds to the lower WHO-2013 diagnostic criteria. The aim of this study was to determine whether the switch from previous Swedish

A search for supersymmetry targeting the direct production of winos and higgsinos is conducted in final states with either two leptons (e or μ) with the same electric charge, or three leptons. The analysis uses 139 fb−1 of pp collision data at (Formula presented.) TeV collected with the ATLAS detector during Run 2 of the Large Hadron Collider. No significant excess over the Standard Model expectat