Population ageing is making it increasingly diffcult for countries to sustain their current levels social welfare transfers from the economically active population to the dependent elderly. To meet this challenge, the Swedish government has implemented various reforms since the 1990s aimed at reducing incentives to take early retirement. However, a critical question has emerged in response to thes

Background: Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to improve its performance as screening biomarker. Methods: We developed and validated linear and dichotomous (≥3

Background: Most diabetic patients sensitized to FreeStyle Libre react to isobornyl acrylate (IBOA), with a considerable number of them also showing unexpected positive patch test reactions to sesquiterpene lactone (SL) mix (SLM) tested in the baseline series. Objectives: To compile patch test results of subjects affected, and provide potential explanations for this association. Patients and Metho

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood, a problem that is exacerbated by the enormous genetic heterogeneity of this disease group. However, the last decade has yielded a wealth of new knowledge on degenerative pathways and their diversity. Notably, a central role of cGMP-signalling has surfaced for photoreceptor cell death triggered by

Each year, fungal storage diseases destroy large amounts of apple, especially in organic orchards. In the present study, antifungal activity of a rye bran-based remedy with 5-n-alkylresorcinols (ARs) was investigated. In 2014 and 2015, ‘Amorosa’ apple trees in an organic orchard were sprayed with a 0.025% AR emulsion pre-harvest, once or twice at different points in time. In addition, emulsions wi

MicroRNAs (miRNA) play an important role in various biological process by regulating gene expression. Their abnormal expression may lead to cancer. Therefore, analysis of such data may discover potential biological insight for cancer diagnosis. In this regard, recently many feature selection methods have been developed to identify such miRNAs. These methods have their own merits and demerits as th

To the Editor — Ecologists Gardner and Wordley1 recently argued that in the face of “interconnected planetary emergencies threatening our climate and ecosystems,” information on the severity and urgency of the problem is insufficient to promote the necessary social and political change. Thus, “scientists should join civil disobedience movements to fight these unprecedented crises”. That the realiz

Temperaturändringar och krympning påverkar betongkonstruktioners volym, och i konstruktioner som hindras från av röra sig kan sådana volymändringar leda till så kallade tvångseffekter, som i sin tur kan orsaka sprickbildning. När detta sker kan emellertid konstruktionen deformeras till viss del, vilket gör att tvångsspänningarna och därmed också sprickvidderna minskar. Uppsprickningsförloppet är sThermal actions and shrinkage cause volume changes in concrete structures. In structures which are restrained from movements, the restraint effects can cause cracking. However, when cracking occurs, the structure can deform to some extent, which reduces the restraint stresses and thus also the crack widths. As the exact crack development is hard to predict beforehand, the actual restraint and thus

OBJECTIVES: Alcohol use disorders (AUD) is well known to aggregate in families and is associated with socioeconomic status (SES). The objective was to study the effect of education, income and neighborhood SES in adulthood on AUD, and to explore whether the potential associations were confounded by shared familial factors, by using a co-relative control design. METHODS: Data on AUD was drawn from

The circumpolar Arctic is currently facing multiple global changes that have the potential to alter the capacity of tundra soils to store carbon. Yet, predicting changes in soil carbon is hindered by the fact that multiple factors simultaneously control processes sustaining carbon storage and we do not understand how they act in concert. Here, we investigated the effects of warmer temperatures, en

Countering fear and promoting experiences of security and safety among visitors are key issues in creating socially sustainable urban destinations. Security branding is a growing place branding paradigm through which to enhance experiences and perceptions of safety in cities, nations and regions (Coaffee and Van Ham, 2008; Coaffee and Rogers, 2008; Avraham and Ketter, 2008). This paper discusses h

Kinesisk översättning av en serie av mina engelska artiklar

In various conceptual models, the shape parameter (β) of the storage capacity curve, representing the non-linear relationship between relative soil moisture and runoff, determines runoff yield given certain circumstances of rainfall and antecedent soil moisture. In practice, β is typically calibrated for individual catchments and for different purposes, which limits more systematic understanding a

Based on two long-term, hourly (10:30-11:30 and 13:10-14:10) meteorological over-lake observations and data from Shenxian meteorological station, nearby Dongping Lake, the Penman-Monteith equation and reference evaporation ratio algorithm were used to calculate lake evaporation in Dongping Lake, China, from 2003 to 2010. The variation trend of evaporation of Dongping Lake was analyzed, and the inf