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The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial

Granulocyte chemotactic protein 2 (GCP-2)/CXCL6 is a CXC chemokine expressed by macrophages and epithelial and mesenchymal cells during inflammation. Through binding and activation of its receptors (CXCR1 and CXCR2), it exerts neutrophil-activating and angiogenic activities. Here we show that GCP-2/CXCL6 itself is antibacterial. Antibacterial activity against gram-positive and gram-negative pathog

Nya riktlinjer behövs för verifiering och kontroll av byggtekniskt brandskydd!

Kraven på mera avancerade verifieringsmetoder har ökat i takt med att det traditionella sättet att projektera en byggnads brandskydd har förändrats, samt att vi idag är mer medvetna om vilka riskerna är, t ex att tillförlitlighet i tekniska skyddssystem måste beaktas. Detta är nödvändigt för att säkerställa att samhällets krav på brandsäkerhet efterlevs och uppfylls.

PITX2 gain-of-function induced defects in mouse forelimb development.

BACKGROUND: Limb development and patterning originate from a complex interplay between the skeletal elements, tendons, and muscles of the limb. One of the genes involved in patterning of limb muscles is the homeobox transcription factor Pitx2 but its role in forelimb development is uncharacterized. Pitx2 is expressed in the majority of premature presumptive forelimb musculature at embryonic day 12

Systematisk journalgranskning i Skåne - Diagnoskoder var ofta fel vid svår sepsis och septisk chock.

The reliability of official registers of diagnosis depends on proper adherence to guidelines for diagnosis and diagnosis coding. Such guidelines for severe sepsis and septic shock have changed over the years, reflecting improved knowledge of these serious conditions. In order to investigate the compliance to current Swedish guidelines for diagnosis and coding of severe sepsis and septic shock, we

An analysis of the block error probability performance of iterative decoding

Asymptotic iterative decoding performance is analyzed for several classes of iteratively decodable codes when the block length of the codes N and the number of iterations I go to infinity. Three classes of codes are considered. These are Gallager's regular low-density parity-check (LDPC) codes, Tanner's generalized LDPC (GLDPC) codes, and the turbo codes due to Berrou et al. It is proved that ther

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Review of "Across the North Sea. Later Historical Archaeology in Britain and Denmark, c. 1500-2000 AD" (2012)