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Brain disorders affect the normal functionality of the brain causing inability in controlling certain behaviours. In the last two decades, despite the technological advancement, many biological questions concerning brain mechanisms and neural networks remain still unclear. Thus, the integration of multiple technologies could help on clarify several aspects of neurobiology.The aim of this thesis wa
Resilience is a debated concept with numerous definitions. If focusing on describing a community under stress of a particular disruptive event, its more traditional etymological meaning of ability to spring back after deformation, or its more applied meaning of ability to cope with and recover from the event, are sufficient. However, if focusing on building and maintaining resilient communities ov
In the aftermath of the global financial crisis, the financial sector globally has become much more reg-ulated to ensure ’ethical’ conduct, yet we have still to understand how the banks has worked to ensure a more cultural shift towards ethical conduct. The purpose of our paper is to examine the cultural changes in three different retail banks, focusing specifically on ethical sales and advising a
Why are some states more corrupt than others? Drawing on the literature on governance in parliamentary democracies, we suggest that the degree of corruption depends on the ability of key political actors to control ministers who have been delegated power. We argue that the Prime Minister has incentives to limit corruption within the cabinet and has the ability to do so when there are certain “cont
Background: Topical oestrogen and manual separation are the main treatments for labial adhesions. The aim was to evaluate treatment of labial adhesions and compare the outcome of topical oestrogen treatment with that of manual separation. Method: All girls aged 0-12 years admitted to a tertiary centre for paediatric surgery for labial adhesions were included. The study design was dual: The first p
Objective To investigate whether oral fluoroquinolone use is associated with an increased risk of aortic aneurysm or dissection. Design Nationwide historical cohort study using linked register data on patient characteristics, filled prescriptions, and cases of aortic aneurysm or dissection. Setting Sweden, July 2006 to December 2013. Participants 360 088 treatment episodes of fluoroquinolone use (
This paper describes an expedition to map a first century B.C. ship wreck off the coast of the Greek island of Antikythera using an Autonomous Underwater Vehicle (AUV) equipped with a high-resolution stereo imaging system. The wreck, first discovered in 1900, has yielded a wealth of important historical artefacts from two previous interventions, including the renowned Antikythera mechanism. The de
The processing of emotional signals usually causes an increase in pupil size, and this effect has been largely attributed to autonomic arousal prompted by the stimuli. Additionally, changes in pupil size were associated with decision making during non-emotional perceptual tasks. Therefore, in this study we investigated the relationship between pupil size fluctuations and the process of emotion rec
Sound and radio can be used to estimate the distance between a transmitter and a sender by correlating the emitted and received signal. Alternatively by correlating two received signals it is possible to estimate distance difference. Such methods can be divided into methods that are robust to noise and reverberation, but give limited precision and sub-sample refinements that are sensitive to noiseSound and radio can be used to estimate the distance between a transmitter and a sender by correlating the emitted and received signal. Alternatively by correlating two received signals it is possible to estimate distance difference. Such methods can be divided into methods that are robust to noise and reverberation, but give limited precision and sub-sample refinements that are sensitive to noise
Different starchy foods are frequently consumed in the Mexican diet. Some of them were developed by Pre-Columbian Mesoamerican civilizations. Until today, common beans (Phaseolus vulgaris), tortillas made with maize (Zea mays) and related maize-based products are some of the main staple foods. Additionally, wheat-based foods are also important starch sources, incorporated in different dishes. This
Mixed pathologies of α-synuclein, β-amyloid and tau are relatively common in Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB). We therefore wanted to study the retention patterns of 18F-AV-1451 in PD, PD-dementia (PDD), and DLB. To do this 44 healthy controls, 11 non-demented patients with PD, 18 patients with PDD, and six patients with DLB underwent MRI and 18F-AV-1451 PET scanning an
Sulfite oxidase is a mononuclear molybdenum enzyme that oxidises sulfite to sulfate in many organisms, including man. Three different reaction mechanisms have been suggested, based on experimental and computational studies. Here, we study all three with combined quantum mechanical (QM) and molecular mechanical (QM/MM) methods, including calculations with large basis sets, very large QM regions (80
