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BACKGROUND AND OBJECTIVES: Amerindians are blood group O, but the distribution of the various O alleles is unknown. Their ABO genotypes were compared with samples from other Brazilian ethnic groups. MATERIALS AND METHODS: Genomic DNA was examined by PCR-RFLP analysis, PCR-SSP and direct sequencing. RESULTS: An unusual allele distribution was found, with 91% of the O alleles being O1variant. Almost
This study was performed to elucidate circulatory changes in the fetal cerebral circulation during uncomplicated labor and in early neonatal life. Eighteen healthy term singleton fetuses were followed longitudinally during labor. Using the transabdominal approach, and the color Doppler technique, the middle cerebral artery was identified and Doppler flow velocity waveforms recorded between and dur
The aim of the study was to identify mechanisms acting at internal frost destruction of concrete. By 'internal frost destruction' is meant damage caused inside concrete that is moisture insulated from the surroundings, i.e. when no moisture exchange with the surroundings is possible during freeze-thaw. Thus, the aim was not to investigate destruction processes (scaling) taking place at the surface
Popular Abstract in Swedish Varför lyckas EU-länderna allt oftare agera gemensamt i frågor som rör internationell fred och säkerhet? Genom att först visa hur volymen och innehållet i Unionens gemensamma utrikes- och säkerhetspolitik har expanderat sedan 1970, närmar sig denna studie ovanstående fråga från tre olika vinklar: Är det först och främst gradvisa institutionella förändringar som möjliggjIt is difficult for states to cooperate on issues related to international peace and security. Yet, ever since 1970, the EU member states have succeeded to gradually intensify their foreign policy cooperation and increasingly act in unison towards the rest of the world. This PhD thesis seeks an explanation to this trend. It does so by initially painting a picture of when, in time, the volume and c
During normal cooking of meat, a class of mutagenic/carcinogenic compounds called heterocyclic amines is formed. Heterocyclic amines are rapidly absorbed and metabolised in the human body, and for estimation of the intake of heterocyclic amines, it is useful to determinate their levels in the urine. Blue Chitin columns were used for the extraction and purification of heterocyclic amines from urine
The complex [(IMesH2)(PPh2Cy)Cl2RuCHPh] was synthesised and shown to be an active catalyst in ring-closing metathesis of a diallylmalonate. Its phosphine exchange was investigated in C6D6 using magnetisation transfer 31P NMR spectroscopy and it was found to operate via a dissociative mechanism with k353 = 4.1 ± 0.9 s−1, ΔH‡ = 84 ± 10 kJ mol−1 and ΔS‡ = 4 ± 28 J mol−1 K−1.
Antibody microarray is a novel technology that will allow us to efficiently perform global proteome analysis. Performing rapid and multiplexed analysis on complex proteomes, such as human serum, targeting also low-abundant analytes will, however, place high demands upon the microarray design with respect to logistics, specificity and sensitivity. In this study, we have shown that non-purified affi
This paper discusses two feasibility studies of Genetic Programming (GP) to the field of control theory, GP being a method inspired from nature where the goal is to create a computer program automatically from high-level statements of problems' requirements. The first feasibility study derives from stability theory and deals with evolving a program that can solve discrete-time Lyapunov equations.
The difference between the resolvents of two selfadjoint extensions of a certain symmetric operator A is described by Krein's resolvent formula. We will prove an analog of Krein's formula in a general framework, apply it to extensions theory, and give a straightforward proof of Krein's formula including the case that A is not necessarily densely defined. We will also present a modification of Krei
This work was conducted to study the potential of molecularly imprinted polymers (MIPs) for the removal of oestradiol at trace concentrations (1 ppm - 1 ppb). An MIP synthesised with 17 beta-oestradiol as template was compared to non-imprinted polymers (NIP) synthesised under the same conditions but without template, a commercial C18 extraction phase and granulated activated carbon. At 1 ppb,oestr
A Saccharomyces cerevisiae screening strain was designed by combining multiple genetic modifications known to improve xylose utilization with the primary objective of enhancing xylose growth and fermentation in xylose isomerase (XI)-expressing strains. Strain TMB 3045 was obtained by expressing the XI gene from Thermus thermophilus in a strain in which the GRE3 gene coding for aldose reductase was
Calcitonin gene-related peptide and adrenomedullin belong to a structurally related neuropeptide family and are potent vasodilators expressed in the trigeminovascular system. The molecular identity of receptors for these proteins has only recently been elucidated. Central to functional binding of these neuropeptides is the G-protein-coupled receptor, the calcitonin receptor-like receptor (CRLR), W
Redox hydrogel-based micropatterned complex biosensor architectures, used as sensing chemistries in amperometric ethanol or glucose biosensors, were deposited on gold, graphite or glass. Well-localized immobilization of active hydrogels with variable compositions was achieved by dispensing 100 pl droplets of cocktails containing alcohol or glucose dehydrogenase, redox polymer (PVI(13)dmeOs) and cr
Formoterol administered by a dry-powder (DP) capsule inhaler was compared with a pressurized metered-dose inhaler (pMDI) with regard to bronchodilating and systemic effects. The study used a double-blind, crossover, double-dummy technique. Twelve patients with moderate reversible asthma in a stable phase were examined on two separate study days, and the inhalers were given in randomized order. Aft
Breast cancer is the most common form of malignancy affecting women in the Western world. Today, anticancer treatment can control primary breast tumors, but treatment and prevention of metastatic disease still represents a major challenge in the management of breast cancer patients. It has been shown that Wnt-5a plays an important role in breast cancer, since loss of that protein is associated wit
An 8-GHz beamforming transmitter IC has been designed in a 130-nm CMOS process. Two power amplifiers with independently controllable phase enable the beamforming. The phases are digitally controllable over the full 360° range, which is accomplished by binary weighting of quadrature phase signals in the power amplifiers. The quadrature phase signals are generated by a quadrature voltage controlled
Photoelectron spectra of Sr and Ca shallow core levels in Bi2Sr2CaCu2O81, (Bi2212) single crystals exhibit a strong attenuation effect because the photoelectron escape depth is very short in this material. This results may have a strong impact on the interpretation of ARPES and STM spectra near the Fermi level since it suggests the electronic states of planes other than CuO play a role in both tun
